Zomepirac Acyl-O-β-D-glucuronide

CAS: 75871-31-7

Ref. TR-Z675010

Product Information

• Name: Zomepirac Acyl-O-β-D-glucuronide
• Synonyms: 1-[5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate] ß-D-Glucopyranuronic Acid, Zomepirac Glucuronide, Zomepirac Acyl-1-O-ß-D-glucuronide, β-D-Glucopyranuronic acid, 1-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate], Zomepirac glucuronide

Description

Stability Hygroscopic
Applications An unstable metabolite of the nonsteroidal anti-inflammatory drug (NSAID) Zomepirac (Z675000) that is capable of reacting with endogenous proteins to form potentially toxic covalent ZP-protein adducts.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References King, A.R. et al.: J. Phamacol. Toxicol. Meth., 36, 131 (1996); Olsen, J. et al.: Chem. Res. Toxicol., 18, 1729 (2005); O’Neill, P.J. et al.: J. Clin. Pharmacol., 22, 470 (1982);

• Brand: TRC

Chemical properties

• Molecular weight: 467.85
• Formula: C₂₁H₂₂ClNO₉
• Color/Form: Beige
• InChI: InChI=1S/C21H22ClNO9/c1-9-7-12(23(2)14(9)15(25)10-3-5-11(22)6-4-10)8-13(24)31-21-18(28)16(26)17(27)19(32-21)20(29)30/h3-7,16-19,21,26-28H,8H2,1-2H3,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1
• InChI key: InChIKey=FNGKIZYZSHHXJZ-ZFORQUDYSA-N
• SMILES: Cc1cc(CC(=O)O[C@@H]2O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]2O)n(C)c1C(=O)c1ccc(Cl)cc1