Zonisamide-d4

CAS: 1020720-04-0

Ref. TR-Z700002

Product Information

• Name: Zonisamide-d4
• Synonyms: (4,5,6,7-tetradeuterio-1,2-benzoxazol-3-yl)methanesulfonamide

Description

Applications Labelled sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Anticonvulsant.
References Masuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980), Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1987), Schmidt, D., et al.: Epilepsy Res., 15, 67 (1993), Sorkin, E.M., et al.: Drugs, 45, 760 (1993),

• Brand: TRC

Chemical properties

• Molecular weight: 216.25
• Formula: C₈H₄H₄N₂O₃S
• Color/Form: Light Brown Solid
• InChI: InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)/i1D,2D,3D,4D
• InChI key: InChIKey=UBQNRHZMVUUOMG-RHQRLBAQSA-N
• SMILES: [2H]c1c([2H])c([2H])c2c(CS(N)(=O)=O)noc2c1[2H]