Zonisamide-13C2-15N

CAS: 1188265-58-8

Ref. TR-Z700003

Product Information

• Name: Zonisamide-13C2-15N
• Synonyms: 1,2-Benzisoxazole-13C2-3-methanesulfonamide-15N, 3-(Sulfamoyl-15N-methyl)-1,2-benzisoxazole-13C2, AD 810-13C2-15N, Aleviatin-13C2-15N, Excegran-13C2-15N, PD 110843-13C2-15N, Zonegran-13C2-15N

Description

Applications Zonisamide-13C2-15N is the labeled analogue of Zonisamide (Z700000), a sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Anticonvulsant.
References Masuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980); Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1987); Schmidt, D., et al.: Epilepsy Res., 15, 67 (1993); Sorkin, E.M., et al.: Drugs, 45, 760 (1993)

• Brand: TRC

Chemical properties

• Molecular weight: 215.2
• Formula: C₆₁₃C₂H₈N₁₅NO₃S
• Color/Form: Neat
• InChI: InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)/i5+1,7+1,9+1
• InChI key: InChIKey=UBQNRHZMVUUOMG-VDWPWFDKSA-N
• SMILES: [15NH2]S(=O)(=O)[13CH2][13c]1noc2ccccc21