Product Information
- 2-(Difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-1H-benzimidazole
- 1H-Benzimidazole, 2-(difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-
- 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine
- 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-dimorpholino-1,3,5-triazine
- Tcmdc-137004
- Zstk 474
- Zstk474
- 4,4′-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine
Applications ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase (PI3K) isoforms. Potent PI3K inhibitor.
References Yaguchi, S., et al.: J. Natl. Cancer Inst., 98, 545 (2006); Kong, D., et al.: Cancer Sci., 98, 1638 (2007); Kong, D., et al.: Eur. J. Cancer, 45, 857 (2009); Marone, R., et al.: Mol. Cancer Res., 7, 601 (2009); Yang, S., et al.: PLoS One, 6, e26343 (2011); Haruta, K., et al.: Inflamm, Res., 61, 551 (2012);
Chemical properties
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