CAS 21259-20-1

Toxina T 2

Descrição:

Toxina T 2, com o número CAS 21259-20-1, é uma micotoxina produzida por certas espécies de fungos, particularmente aqueles do gênero Fusarium. É classificada como um tricoteceno, um grupo de toxinas conhecidas por sua capacidade de inibir a síntese de proteínas em células eucarióticas, levando a uma série de efeitos tóxicos. Toxina T 2 é caracterizada por sua potente citotoxicidade e propriedades imunossupressoras, que podem afetar tanto a saúde humana quanto a animal. A exposição a essa toxina pode ocorrer através de alimentos ou ração contaminados, e está associada a vários problemas de saúde, incluindo distúrbios gastrointestinais, irritação da pele e efeitos sistêmicos mais graves em doses mais altas. O composto também é conhecido por sua estabilidade sob várias condições ambientais, tornando-se uma preocupação em contextos agrícolas. Devido à sua toxicidade, Toxina T 2 está sujeito a escrutínio regulatório, e esforços são feitos para monitorar e limitar sua presença em produtos alimentícios para garantir a segurança.

Fórmula: C₂₄H₃₄O₉

InChI: InChI=1/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24-/m0/s1

Chave InChI: InChIKey=BXFOFFBJRFZBQZ-QYWOHJEZSA-N

SMILES: C[C@@]12[C@@]3([C@@]([C@H](O)[C@H]1OC(C)=O)(O[C@]4([C@]2(COC(C)=O)C[C@H](OC(CC(C)C)=O)C(C)=C4)[H])[H])CO3

Sinónimos:

• (3Α,4Β,8Α)-12,13-Epoxytrichothec-9-Ene-3,4,8,15-Tetrol 4,15-Diacetate 8-(3-Methylbutyrate)
• (3α,4β,8α)-12,13-Epoxytrichothec-9-en-3,4,8,15-tetrol-4,15-diacetat-8-(3-methylbutyrat)
• 4,15-Diacetate-8-(3-Methylbutyrate) De (3Α,4Β,8Α)-12,13-Epoxytrichothec-9-Ene-3,4,8,15-Tetrol
• 4,15-Diacetato-8-(3-Metilbutirato) De (3Α,4Β,8Α)-12,13-Epoxitricotec-9-Eno-3,4,8,15-Tetrol
• 4β,15-Diacetoxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-en-3α-ol
• 8α-(3-Methylbutyryloxy)-4β,15-diacetoxyscirp-9-en-3α-ol
• Fusariotoxin T 2
• Insariotoxin
• Mycotoxin T 2
• Nsc 138780
• Spiro[2,5-methano-1-benzoxepin-10,2′-oxirane], trichothec-9-ene-3,4,8,15-tetrol deriv.
• T 2
• T 2 Toxin
• T 2 mycotoxin
• T-2 Lienomycin
• Toxin T 2
• Trichothec-9-ene-3α,4β,8α,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-isovalerate
• (3beta,4alpha,8alpha)-4,15-bis(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-(3-methylbutanoate), (3α,4β,8α)-
• T-2 toxin from fusarium sp
• Epoxytrichothecene, Fusariotoxin T 2, Mycotoxin T 2
• 3alpha-hydroxy-4beta-15-diacetoxy-8alpha-(3-methylbutyryloxy)-12,13-epoxy-delt
• 3-hydroxy-4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta(sup9)-tric
• 12,13-epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate
• trichothec-9-ene-3,4,8,15-tetrol,12,13-epoxy-,4,15-diacetate8-(3-methylbutan
• 3-hydroxy-4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta-(sup9)-trich
• 3-hydroxy-4,15-diacetoxy-8-[3-methylbutyryloxy]-12,13-epoxytrichothec-9-ene
• a9-tricothecene[qr]
• 4BETA,15-DIACETOXY-3ALPHA-HYDROXY-8ALPHA-[3-METHYLBUTYRYLOXY]-12,13-EPOXYTRICHOTHEC-9-ENE
• -isovalerate
• nsc138780[qr]
• 100 ug/ml T-2 Toxin in ACN
• 4-beta,15-diacetoxy-8-alpha-(3-methylbutyryloxy)-3-alpha-hydroxy-12,13-epoxy
• 13C24]-T-2 toxin-25 μg/mL in ACN
• 8-(3-methylbutyryloxy)-diacetoxyscirpenol[qr]
• T-2 Toxin, 99%, from Fusarium tricinctum
• t2-trichothecene[qr]
• 8alpha-(3-Methylbutyryloxy)-4beta,15-diacetoxyscirp-9-en-3alpha-ol
• CAS21259-20-1 T-2 TOXIN
• T2 Toxin / Fusariotoxin T 2 / Insariotoxin / Mycotoxin T 2
• T2 toxin 100ug/ml in ACN
• hothecene
• 12,13-trichothecene
• Fusariotoxin T2: (T2-Trichothecene)
• FUSARITOXIN
• 8α-(3-Methylbutyryloxy)-4β,15-
• Trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-isovalerate
• t-2mycotoxin[qr]
• 12,13-EPOXYTRICHOTHECENE
• T-2 Toxin Solution in Acetonitrile, 100μg/mL
• 8alpha-(3-methylbutyryloxy)-4beta,15-diacetoxyscirp-9-en-3alpha-ol[qr]
• 8-(3-Methylbutyryloxy)diacetoxyscirpenol
• 3alpha-Hydroxy-4beta,15-diacetoxy-8alpha(3-methylbutyryloxy)-12,13-epoxy-trichothec-9-ene
• 4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta-9-trichothecen-3-ol
• (3-ALPHA, 4-BETA, 8-ALPHA)-TRICHOTHEC-9-ENE-3,4,8,15-TETROL,12,13-EPOXY-, 4,15-DIACETATE 8-(3-METHYLBUTANOATE)
• 8-(3-methylbutyryloxy)-diacetoxyscirpenol
• 12,13-epoxytrichothec-9-ene-3alpha,4beta,8alpha,15-tetrol,4,15-diacetate8-isov
• (3-alpha, 4-beta, 8-alpha)-Trichothec-9-ene-3,4,8,15-tetrol,12,13-epoxy-, 4,15-diacetate 8-(3-methylbutanoate), Mycotoxin Trichothecene 2, Fusariotoxin
• 4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta-9-trichothecen-3-ol[qr
• U-[13C24]-T-2 Toxin Solution in Acetonitrile, 25μg/mL
• MYCOTOXIN TRICHOTHECENE 2
• alerate[qr]
• 4β,15-Diacetoxy-3α-hydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene, 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate
• EPOXYTRICHOTHECENE
• isaritoxin[qr]
• 12,13-epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol4,15-diacetate8
• T-2TRICHOTHECENE
• 4β,15-Diacetoxy-8α-(3-Methylbutyryloxy)-
• T-2-toxin vial with 5 mg
• 12,13-epoxytrichothec-9-ene-3,4,8,15-tetrol4,15-diacetate8-(3-methylbutanoate
• T-2 Toxin (T-2 Mycotoxin)
• toxint2
• trichothec-9-ene
• 4beta,8alpha,15-tetrol,12,13-epoxy-,4,15-diacetate8-trichothec-9-ene-3alph
• (3α,4β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-Diacetate 8-(3-Methylbutanoate)
• T-2 Toxin,12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate, 4β,15-Diacetoxy-3α-hydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
• (3alpha,4beta,8alpha)-12,13-epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-diacetate 8-(3-methylbutyrate)
• (3alpha,4beta,8alpha)-oate
• 4,15-diacetoxy-8-(3-methylbutyryloxy)scirp-9-en-3-ol
• 8-isovalerate
• t-2mycotoxin
• fusariotoxinet2
• 8-(3-methylbutyryloxy)-diacetoxy-scirpeno
• fusariotoxinet2[qr]
• T-2 Toxin, froM FusariuM tricinctuM
• 12,13-epoxytrichothec-9-en-3α-ol
• trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol,12,13-epoxy-,4,15-diacetate
• Scirpenol, 8-(3-methylbutyryloxy)-diacetoxy-
• t(sub2)-trichothecene[qr]
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-
• FUSARIOTOXIN
• diacetoxyscirp-9-en-3α-ol
• nsc138780
• othecene[qr]

T-2 Toxin 100 µg/mL in Acetonitrile

Produto Controlado

CAS: 21259-20-1

Fórmula: C₂₄H₃₄O₉

Cor e Forma: Single Solution

Peso molecular: 466.52

Ref: 04-A13989000AL-100

A + B-Trichothecenes and Zearalenone Mixture 10 µg/mL in Acetonitrile

Produto Controlado

CAS: 17924-92-4, 21259-20-1, 2270-40-8, 23255-69-8, 23282-20-4, 26934-87-2, 50722-38-8, 51481-10-8

Cor e Forma: Mixture

Ref: 04-A30000004AL

T-2 Toxin

Produto Controlado

CAS: 21259-20-1

Fórmula: C₂₄H₃₄O₉

Cor e Forma: Neat

Peso molecular: 466.52

Ref: 04-C13989000-5MG

T-2 Toxin

Produto Controlado

CAS: 21259-20-1

Fórmula: C₂₄H₃₄O₉

Cor e Forma: Neat

Peso molecular: 466.52

Ref: 04-C13989000-10MG

Fusarium Toxins Mixture 10-100 µg/mL in Acetonitrile

Produto Controlado

CAS: 17924-92-4, 21259-20-1, 26934-87-2, 51481-10-8, 5975-78-0

Cor e Forma: Mixture

Ref: 04-V30000007AL

T-2 Toxin 100 µg/mL in Acetonitrile

Produto Controlado

CAS: 21259-20-1

Fórmula: C₂₄H₃₄O₉

Cor e Forma: Single Solution

Peso molecular: 466.52

Ref: 04-V13989000AL-100

A + B-Trichothecenes and Zearalenone Mixture 10 µg/mL in Acetonitrile

Produto Controlado

CAS: 17924-92-4, 21259-20-1, 2270-40-8, 23255-69-8, 23282-20-4, 26934-87-2, 50722-38-8, 51481-10-8, 5975-78-0

Cor e Forma: Mixture

Ref: 04-V30000004AL

T-2 Toxin

CAS: 21259-20-1

Fórmula: C₂₄H₃₄O₉

Peso molecular: 466.53

Ref: 4Z-M-214001

T-2 Toxin

CAS: 21259-20-1

Fórmula: C₂₄H₃₄O₉

Pureza: ≥ 98.0%

Cor e Forma: White to off-white solid

Peso molecular: 466.52

Ref: 7W-GW6303

T2 Toxin

Produto Controlado

CAS: 21259-20-1

T2 toxin is a toxin produced by the bacterium Bacillus thuringiensis. It has an inhibitory effect on the polymerase chain reaction (PCR) and is toxic to cells in vitro. T2 toxin inhibits mitochondrial function, which can lead to cell death. T2 toxin also has antioxidant properties, and may have therapeutic potential as a drug transporter. The optimum concentration of T2 toxin for toxicity studies is unknown, but it has been shown that concentrations greater than 10 µg/mL are toxic to cells in vitro. In addition, T2 toxin has been shown to be toxic to human serum and liver cells at high concentrations.

Pureza: Min. 95%

Cor e Forma: Powder

Ref: 3D-BT162749

T-2 Toxin

CAS: 21259-20-1

T-2 Toxin

Fórmula: C₂₄H₃₄O₉

Pureza: By hplc: 98.24% (Typical Value in Batch COA)

Cor e Forma: white powder

Peso molecular: 466.52g/mol

Ref: 54-BIT1041

T-2 Toxin

CAS: 21259-20-1

T-2 Toxin (T-2 Mycotoxin) is a fungal secondary metabolite produced by various Fusarium species in feed and grains, which is highly toxic to reproduction and induces a variety of cardiovascular toxicities.T-2 Toxin is an inhibitor of peptidyl transferase (60s ribosomal subunit) binding and protein synthesis. T-2 Toxin is an inhibitor of peptidyl transferase (60s ribosomal subunit) binding and protein synthesis, induces TM4 cell dysfunction via ROS-induced apoptosis, inhibits DNA and RNA synthesis, and increases hepatic lipid peroxidation levels.

Fórmula: C₂₄H₃₄O₉

Pureza: 98%

Cor e Forma: White Needles From Benzene & Skellysolve B; Acetate Deriv Amorphous Solid From Ether & Pentane Solid

Peso molecular: 466.52

Ref: TM-T13053

T-2 Toxin

Produto Controlado

CAS: 21259-20-1

Applications T-2 Toxin is a tricothecene mycotoxin produced by fungi of the genus Fusarium. T-2 Toxin induces DNA damage and cell death on prolonged administration.Environmental contaminants; Food contaminants
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kim, C., et al.: Cancer Res., 57, 3115 (1997), Bottrel, R., et al.: Antimicrob. Agents Chemother., 1999, 43, 856 (1999), Murray, P., et al.: J. Immunol., 178, 2623 (2007), Choi, H., et al.: Toxicol. Appl. Pharmacol., 240, 46 (2009), Amuzie, C., et al.: Toxicol. Sci., 113, 412 (2010),

Fórmula: C₂₄H₃₄O₉

Cor e Forma: White Solid

Peso molecular: 466.52

Ref: TR-T002980

T-2 Toxin-13C4

Produto Controlado

CAS: 21259-20-1

Fórmula: C₄C₂₀H₃₄O₉

Cor e Forma: Neat

Peso molecular: 470.492

Ref: TR-T002981