CAS 26934-87-2

HT 2 Toxina

Descrição:

HT 2 Toxina, com o número CAS 26934-87-2, é uma micotoxina produzida por certas espécies de fungos, particularmente aqueles pertencentes ao gênero Fusarium. Está principalmente associada a grãos contaminados e pode representar riscos significativos à saúde tanto de humanos quanto de animais. A toxina é conhecida por seu potencial para causar vários efeitos toxicológicos, incluindo imunossupressão e problemas reprodutivos. HT 2 Toxina é classificada como um tipo A de tricoteceno, que se caracteriza por sua capacidade de inibir a síntese de proteínas nas células, levando a efeitos citotóxicos. Sua estrutura química apresenta uma disposição complexa de anéis e grupos funcionais que contribuem para sua atividade biológica. Devido à sua toxicidade, as agências reguladoras monitoram seus níveis em produtos alimentares e de ração para garantir a segurança. O manuseio e os testes adequados são essenciais para mitigar os riscos de exposição, especialmente em contextos agrícolas onde podem estar presentes culturas contaminadas. No geral, HT 2 Toxina é uma preocupação significativa na segurança alimentar e na saúde pública.

Fórmula: C₂₂H₃₂O₈

InChI: InChI=1/C22H32O8/c1-11(2)6-16(24)29-14-8-21(9-27-13(4)23)15(7-12(14)3)30-19-17(25)18(26)20(21,5)22(19)10-28-22/h7,11,14-15,17-19,25-26H,6,8-10H2,1-5H3/t14-,15+,17+,18+,19+,20+,21+,22+/m0/s1

Chave InChI: InChIKey=PNKLMTPXERFKEN-MLXHEQMXSA-N

SMILES: C[C@]12[C@@]3([C@](O[C@]4([C@]1(COC(C)=O)C[C@H](OC(CC(C)C)=O)C(C)=C4)[H])([C@H](O)[C@H]2O)[H])CO3

Sinónimos:

• (2alpha,3beta,4alpha,5alpha,6beta,8beta,11beta,12R)-15-(acetyloxy)-3,4-dihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate
• (3beta,4alpha,8alpha,12R)-15-(acetyloxy)-3,4-dihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate
• 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 15-acetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-
• 12,13-Epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol 15-acetate 8-isovalerate
• 15-Acetoxy-3,4-dihydroxy-8-(3-methylbutyryloxy)-12,13-epoxy delta9-trichothecene
• 3,4-Dihydroxy-15-acetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-Δ⁹-trichothecene
• HT 2 mycotoxin
• Ht-2
• Isovaleric acid, 8-ester with 12,13-epoxytrichothec-9-ene-3α,4β,8α,15-tetrol 15-acetate
• Mycotoxin HT 2
• Nsc 278571
• Spiro[2,5-methano-1-benzoxepin-10,2′-oxirane], trichothec-9-ene-3,4,8,15-tetrol deriv.
• Toxin HT 2
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15 acetate 8-(3-methylbutanoate), (3alpha,4abeta,8alpha)- (9CI)
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)- (9CI)
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate), (3α,4β,8α)-
• Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 15-acetate, 8-isovalerate
• Trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate (8CI)
• Trichothec-9-ene-3α,4β,8α,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate
• HT 2 Toxin
• 3,4-Dihydroxy-15-acetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-Δ9-trichothecene
• (3alpha,4beta,8alpha)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 15-acetate 8-(3-methylbutanoate)
• mycotoxinht2
• T-2, Toxin analog
• HT-2 toxin, FroM FusariuM sp.
• 15-Acetoxy-3alpha-4beta-dihydoxy-8alpha-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
• HT-2 Toxin (3alpha,4beta,8alpha)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 15-acetate 8-(3-methylbutanoate)
• 12,13-Epoxytrichothec-9-ene-3α,4β,8α,15-tetrol 15-acetate 8-(3-methylbutanoate)
• 12,13-epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol15-acetate8-iso
• 4-beta,8-alpha,15-tetrol,12,13-epoxy-,15-acetate,8-trichothec-9-ene-3-alph
• HT-2 toxin 100ug/ml in ACN
• 15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-8ALPHA-[3-METHYLBUTYRYLOXY]-12,13-EPOXYTRICHOTHEC-9-ENE
• HT-2 toxin, 99%, from Fusarium sp.
• Trichothen-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate)
• U-[13C22]-HT-2 Toxin Solution, 25μg/mL
• Pentanoic acid anion
• (3α,4β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 8-(3-Methylbutanoate) 15-Acetate
• 12,13-Epoxytrichothec-9-ene-3α,4β,8α,15-tetro 15-Acetate 8-Isovalerate
• valerate
• ht-2toxin solution
• 15-acetoxy-3α,4β-dihydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
• HT-2 toxin,15-Acetoxy-3α,4β-dihydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
• Trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-

HT-2 toxin

CAS: 26934-87-2

HT-2 toxin

Fórmula: C₂₂H₃₂O₈

Pureza: 99% (tlc) (Typical Value in Batch COA)

Cor e Forma: colourless syrup/ oil

Peso molecular: 424.48g/mol

Ref: 54-BIH1001

HT-2 Toxin 100 µg/mL in Acetonitrile

Produto Controlado

CAS: 26934-87-2

Fórmula: C₂₂H₃₂O₈

Cor e Forma: Single Solution

Peso molecular: 424.48

Ref: 04-A14214000AL-100

Fusarium Toxins Mixture 10-100 µg/mL in Acetonitrile

Produto Controlado

CAS: 17924-92-4, 21259-20-1, 26934-87-2, 51481-10-8, 5975-78-0

Cor e Forma: Mixture

Ref: 04-V30000007AL

HT-2 Toxin 100 µg/mL in Acetonitrile

Produto Controlado

CAS: 26934-87-2

Fórmula: C₂₂H₃₂O₈

Cor e Forma: Single Solution

Peso molecular: 424.48

Ref: 04-V14214000AL-100

A + B-Trichothecenes and Zearalenone Mixture 10 µg/mL in Acetonitrile

Produto Controlado

CAS: 17924-92-4, 21259-20-1, 2270-40-8, 23255-69-8, 23282-20-4, 26934-87-2, 50722-38-8, 51481-10-8, 5975-78-0

Cor e Forma: Mixture

Ref: 04-V30000004AL

A + B-Trichothecenes and Zearalenone Mixture 10 µg/mL in Acetonitrile

Produto Controlado

CAS: 17924-92-4, 21259-20-1, 2270-40-8, 23255-69-8, 23282-20-4, 26934-87-2, 50722-38-8, 51481-10-8

Cor e Forma: Mixture

Ref: 04-A30000004AL

HT-2 Toxin

CAS: 26934-87-2

Fórmula: C₂₂H₃₂O₈

Peso molecular: 424.49

Ref: 4Z-M-214004

HT-2 Toxin

Produto Controlado

CAS: 26934-87-2

HT-2 Toxin is a toxin that is produced by the bacteria Clostridium botulinum. The HT-2 toxin is used as an analytical method to determine the concentration of this toxin in food, and as a research tool for studying the effects of toxins on cell membrane potential. HT-2 Toxin binds to the mitochondria of cells and causes a loss in mitochondrial membrane potential, which leads to cell death. The HT-2 toxin has been shown to be inhibitory at doses below those that would lead to full lethality. It is also highly sensitive to glycosidic bonds, which are found in many foods, such as malonic acid and zearalenone. These two compounds have been shown to be inhibitors of glycosidase enzymes, which may play a role in the detoxification process. The HT-2 toxin can also induce autophagy in cells that are resistant to its toxic effects.

Fórmula: C₂₂H₃₂O₈

Pureza: Min. 95%

Peso molecular: 424.49 g/mol

Ref: 3D-BH162733

HT-2 Toxin

CAS: 26934-87-2

Fórmula: C₂₂H₃₂O₈

Cor e Forma: Solid

Peso molecular: 424.4847

Ref: IN-DA003QY7

HT-2 Toxin-13C-d3

CAS: 26934-87-2

Fórmula: C₂₁₁₃CH₂₉D₃O₈

Peso molecular: 428.50

Ref: 4Z-M-214006

HT-2 Toxin-d3

CAS: 26934-87-2

Fórmula: C₂₂H₂₉D₃O₈

Peso molecular: 427.51

Ref: 4Z-M-214005

HT-2 Toxin

CAS: 26934-87-2

HT-2 Toxin, a deacetylated metabolite of T-2 toxin, impairs protein synthesis and hinders cell proliferation in plants.

Fórmula: C₂₂H₃₂O₈

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 424.49

Ref: TM-T13726

HT-2 Toxin (>85%)

Produto Controlado

CAS: 26934-87-2

Stability Hygroscopic
Applications HT-2 Toxin is a trichothecene group mycotoxin. HT-2 Toxin is the 4-hydroxy analogue of T-2 Toxin (T002980) which has been shown to induce DNA damage and cell death on prolonged administration.Environmental contaminants; Food contaminants
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Weidner, M. et al.: J. Agric. Food Chem., 60, 5676 (2012); Choi, H. et al.: Toxicol. Appl. Pharmacol., 240, 46 (2009); Amuzie, C. et al.: Toxicol. Sci., 113, 412 (2010);

Fórmula: C₂₂H₃₂O₈

Pureza: >85%

Cor e Forma: Off-White

Peso molecular: 424.48

Ref: TR-H671800