CAS 681159-27-3

Fórmula: C14H12N2O4S2

InChI: InChI=1S/C14H12N2O4S2/c1-3-19-14(18)11-8(2)10(21-7-15)13(22-11)16-12(17)9-5-4-6-20-9/h4-6H,3H2,1-2H3,(H,16,17)

Chave InChI: QBVIRPJBDIZKBC-UHFFFAOYSA-N

SMILES: CCOC(=O)C1=C(C(=C(S1)NC(=O)C2=CC=CO2)SC#N)C

CBR-5884

CAS: 681159-27-3

CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.

Fórmula: C₁₄H₁₂N₂O₄S₂

Pureza: 99.97%

Cor e Forma: Solid

Peso molecular: 336.386

Ref: TM-T14884

CBR-5884

CAS: 681159-27-3

CBR-5884

Fórmula: C₁₄H₁₂N₂O₄S₂

Pureza: ≥98%

Peso molecular: 336.39

Ref: 54-BUP05826

5-[(2-Furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylic Acid Ethyl Ester

CAS: 681159-27-3

Fórmula: C₁₄H₁₂N₂O₄S₂

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 336.3861

Ref: IN-DA00FC2G

CBR-5884

CAS: 681159-27-3

Ethyl 5-(furan-2-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate

Fórmula: C₁₄H₁₂N₂O₄S₂

Pureza: 99%

Peso molecular: 336.39

Ref: IN-DG630821

ethyl 4-(cyanosulfanyl)-5-(furan-2-amido)-3-methylthiophene-2-carboxylate

CAS: 681159-27-3

Fórmula: C₁₄H₁₂N₂O₄S₂

Pureza: 99%

Peso molecular: 336.38

Ref: 10-F515190

CBR-5884

CAS: 681159-27-3

CBR-5884 is a synthetic molecule that inhibits the synthesis of fatty acids in cells. It binds to the mitochondrial membrane potential and prevents ATP production. This compound has been shown to be effective in inhibiting cancers and is a noncompetitive inhibitor of fatty acid synthase. The proapoptotic activity of CBR-5884 may result from its ability to induce apoptosis, as well as covalent inhibitors that inhibit cancer cell proliferation.

Fórmula: C₁₄H₁₂N₂O₄S₂

Pureza: Min. 95%

Peso molecular: 336.39 g/mol

Ref: 3D-GCB15927