CAS 70288-86-7

Ivermectina

Descrição:

Ivermectina é um agente antiparasitário de amplo espectro utilizado principalmente na medicina veterinária e na saúde humana para o tratamento de várias infecções parasitárias. Pertence à classe das lactonas macrocíclicas e é derivado da bactéria Streptomyces avermitilis. O composto exibe uma estrutura complexa caracterizada por um grande anel de lactona e múltiplos estereocentros, contribuindo para sua atividade biológica. Ivermectina atua ligando-se aos canais de cloro ativados por glutamato nas células nervosas e musculares dos parasitas, levando à paralisia e morte do organismo. É eficaz contra uma variedade de parasitas, incluindo aqueles que causam cegueira do rio, filariose linfática e sarna. Ivermectina é geralmente bem tolerado, com um perfil de segurança favorável, embora efeitos colaterais possam ocorrer, particularmente em casos de alta carga parasitária. Seu uso se expandiu além das aplicações tradicionais, com pesquisas em andamento explorando suas potenciais propriedades antivirais. O composto é tipicamente administrado por via oral ou tópica, dependendo do tipo de infecção que está sendo tratada.

Fórmula: Unspecified

InChI: InChI=1/C48H74O14.C47H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38;1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3;11-14,18,24-25,27,29-30,32-44,48-49,51H,15-17,19-23H2,1-10H3/b13-12+,27-15+,32-14+;12-11+,26-14+,31-13+/t25?,26-,28-,30-,31-,33+,34?,35-,36-,37-,38?,39-,40+,41-,42-,43+,44-,45+,47+,48+;25-,27-,29-,30-,32+,33?,34-,35-,36-,37?,38-,39+,40-,41+,42-,43-,44+,46+,47+/m00/s1

Sinónimos:

• 22,23-Dihydroavermectin
• 22,23-Dihydroavermectin B1
• 22,23-Dihydroavermectin B₁
• Bagomectina
• Bimectin
• Bovinet
• Cardomec
• Cardotek 30
• Cardotek Plus
• Cevamec
• Equimec
• Equimec Paste
• Equimectrin
• Equirat Gold
• Eqvalan
• Heartgard
• Heartgard 30
• Hyvermectin
• Ivectin
• Ivermec
• Ivermectin B1a-ivermectin B1b mixture
• Ivermectin Injection
• Ivermectina
• Ivermectine
• Iversalt
• Ivertin
• Ivomec
• Ivomec Gold
• Ivosint
• Jetamec
• L 640471
• Mectizan
• Mk 933
• Mk-0933
• Mukhnet I
• Noramectin
• Noromectin
• Oramec
• Oramectin
• Pandex
• Phoenectin
• Solantra
• Soolantra
• Stromectol
• Uvemec
• Vermic
• Vetmec
• Virbamec LA
• Zimecterin

Ivermectin

CAS: 70288-86-7

Fórmula: C₄₈H₇₄O₁₄

Pureza: >93.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 875.11

Ref: 3B-I0819

Ivermectin

CAS: 70288-86-7

It is used as a positive allosteric modulator of the 7 neuronal nicotinic acetylcholine receptor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar p

Fórmula: C₉₅H₁₄₆O₂₈

Cor e Forma: Powder, White to pale cream

Peso molecular: 1736.19

Ref: 02-J62777

Ivermectin

CAS: 70288-86-7

Ivermectin

Fórmula: C₄₈H₇₄O₁₄

Pureza: 87.6%

Cor e Forma: White To Off-White

Peso molecular: 874.50786

Ref: 47-864

IVERMECTIN CRS

CAS: 70288-86-7

IVERMECTIN CRS

Fórmula: C₉₅H₁₄₆O₂₈

Cor e Forma: Powder

Ref: 41-I8000010

IVERMECTIN RS

CAS: 70288-86-7

IVERMECTIN RS

Ref: 41-ICRS73066

Ivermectin

CAS: 70288-86-7

Lactones, nesoi

Fórmula: H₂B₁a(C₄₈H₇₄O₁₄)H₂B₁b(C₄₇H₇₂O₁₄)

Cor e Forma: White Light Yellow Crystalline Powder

Ref: 45-1354309

Ivermectin

CAS: 70288-86-7

Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.

Fórmula: C₄₈H₇₄O₁₄

Pureza: 94.11% - 99.71%

Cor e Forma: Solid

Peso molecular: 875.09

Ref: TM-T1131

Ivermectin

CAS: 70288-86-7

Fórmula: C₄₈H₇₄O₁₄(H₂B₁a)

Pureza: ≥ 95.0% (dry basis, H2B1a + H2B1b)

Cor e Forma: White to light-yellow crystalline powder

Peso molecular: 875.11 (H2B1a)

Ref: 7W-GA9725

Ivermectine 100 µg/mL in Acetonitrile

CAS: 70288-86-7

Fórmula: C₄₈H₇₄O₁₄·C₄₇H₇₂O₁₄

Cor e Forma: Single Solution

Peso molecular: 1736.16

Ref: 04-XA14488000AL

LC PestiMix 4 10 µg/mL in Acetonitrile

CAS: 103055-07-8, 10311-84-9, 103112-35-2, 113614-08-7, 114-26-1, 114369-43-6, 1172134-12-1, 117428-22-5, 117704-25-3, 120983-64-4, 1216-44-0, 122836-35-5, 123997-26-2, 125225-28-7, 126833-17-8, 129558-76-5, 129630-19-9, 13067-93-1, 13141-86-1, 131983-72-7, 135590-91-9, 13684-63-4, 137641-05-5, 14255-72-2, 142891-20-1, 143807-66-3, 149961-52-4, 163520-33-0, 165108-07-6, 179101-81-6, 189278-12-4, 19044-88-3, 203313-25-1, 220899-03-6, 2274-67-1, 229977-93-9, 2303-17-5, 23031-36-9, 2314-09-2, 24353-61-5, 2439-01-2, 24691-80-3, 2600-69-3, 2655-15-4, 26644-46-2, 30558-43-1, 31251-03-3, 33399-00-7, 35256-85-0, 35575-96-3, 3761-41-9, 38083-17-9, 39184-27-5, 39184-59-3, 40487-42-1, 42509-80-8, 50512-35-1, 50563-36-5, 51218-49-6, 5131-24-8, 54406-48-3, 555-37-3, 56425-91-3, 581809-46-3, 60-51-5, 60207-31-0, 60238-56-4, 6132-17-8, 6552-21-2, 69581-33-5, 70124-77-5, 70288-86-7, 71751-41-2, 7292-16-2, 76674-21-0, 78-34-2, 79622-59-6, 81406-37-3, 83121-18-0, 83657-24-3, 86-50-0, 86479-06-3, 87237-48-7, 87674-68-8, 95617-09-7, 98730-04-2, 98886-44-3, 99607-70-2

Cor e Forma: Mixture

Ref: 04-A50000804AL

Ivermectine

Produto Controlado

CAS: 70288-86-7

Fórmula: C₄₈H₇₄O₁₄·C₄₇H₇₂O₁₄

Cor e Forma: Neat

Peso molecular: 1736.16

Ref: 04-CA14488000

PharmaVetResiMix 1 Avermectins-v6 10 µg/mL in Methanol

Produto Controlado

CAS: 113507-06-5, 117704-25-3, 123997-26-2, 155569-91-8, 70288-86-7, 71751-41-2

Cor e Forma: Mixture

Ref: 04-A30000031ME

Smart Solutions™ v59 PharmaVetResiMix Kit 1

CAS: 100-90-3, 113507-06-5, 115550-35-1, 117704-25-3, 119478-55-6, 122-11-2, 1220-83-3, 123997-26-2, 127-71-9, 127-79-7, 144-82-1, 144-83-2, 14698-29-4, 148-79-8, 149676-40-4, 155569-91-8, 19562-30-2, 20559-55-1, 2447-57-6, 28657-80-9, 31430-15-6, 31431-39-7, 389-08-2, 42835-25-6, 43210-67-9, 515-64-0, 51940-44-4, 53716-50-0, 54029-12-8, 54965-21-8, 57-67-0, 57-68-1, 58306-30-2, 59-40-5, 63-74-1, 651-06-9, 68-35-9, 68786-66-3, 70288-86-7, 70458-96-7, 71751-41-2, 72-14-0, 723-46-6, 729-99-7, 74011-58-8, 75184-71-3, 79660-72-3, 80-08-0, 80-32-0, 80-35-3, 80983-34-2, 82419-36-1, 85721-33-1, 88254-99-3, 91296-86-5, 91296-87-6, 93106-60-6, 948-71-0, 98079-52-8

Cor e Forma: Mixture

Ref: 04-K30000030

GB 23200.121-2021 Pesticide Mixture 8 50 µg/mL in Acetonitrile:Methanol

Produto Controlado

CAS: 101205-02-1, 107534-96-3, 111479-05-1, 111988-49-9, 117428-22-5, 119446-68-3, 121-21-1, 129630-19-9, 131860-33-8, 133855-98-8, 134098-61-6, 135186-78-6, 143390-89-0, 148477-71-8, 153233-91-1, 153719-23-4, 19666-30-9, 2312-35-8, 238410-11-2, 283594-90-1, 28434-01-7, 39300-45-3, 39515-41-8, 40596-69-8, 50512-35-1, 51-03-6, 51338-27-3, 51630-58-1, 52645-53-1, 52918-63-5, 55179-31-2, 55219-65-3, 69806-50-4, 70288-86-7, 76578-14-8, 77501-63-4, 77501-90-7, 80844-07-1, 82657-04-3, 83-79-4, 83657-24-3, 850881-70-8, 88671-89-0, 935545-74-7, 94361-06-5, 95737-68-1

Cor e Forma: Mixture

Ref: 04-A50000728MC

Ivermectin

CAS: 70288-86-7

Fórmula: C₄₈H₇₄O₁₄

Peso molecular: 875.12

Ref: 4Z-I-077001

Ivermectin-d2

Produto Controlado

CAS: 70288-86-7

Applications Isotope labelled Ivermectin, is the labeled analogue of Ivermectin (I940800), which is a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980), Campbell, W.C., et al.: Science, 221, 823 (1983), Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988), Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995), ; Caly, L., et al.: Antivir. Res., 178

Fórmula: C₄₈H₇₂D₂O₁₄

Cor e Forma: Neat

Peso molecular: 877.11

Ref: TR-I940802

Ivermectin

Produto Controlado

CAS: 70288-86-7

Applications Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Anthelmintic (Onchocerca).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);

Fórmula: C₄₈H₇₄O₁₄·C₄₇H₇₂O₁₄

Cor e Forma: White To Off-White

Peso molecular: 1736.16

Ref: TR-I940800

Ivermectin - Bio-X ™

CAS: 70288-86-7

Naturally produced by the soil bacterium Streptomyces avermitili, Ivermectin is clinically used in the treatment of parasitosis in both humans and animals. Ivermectin is commercially available as a mixture of 80% 22, 23-dihydroavermectin B1a and 20% 22, 23-dihydroavermectin B1b. In 2020, research indicated that it was a good antiviral agent in the treatment of SARS-CoV-2 and a new mechanism of action has been suggested. Ivermectin would act on importin α/β heterodimer and affect nuclear transport and the translocation of viral proteins.

Fórmula: C₄₈H₇₄O₁₄

Pureza: (%) Min. 95%

Cor e Forma: Powder

Peso molecular: 875.09 g/mol

Ref: 3D-BI166167

Ivermectin

CAS: 70288-86-7

Naturally produced by the soil bacterium Streptomyces avermitili, it is clinically used in the treatment of parasitosis in both humans and animals. Ivermectin is commercially available as a mixture of 80% 22, 23-dihydroavermectin B1a and 20% 22, 23-dihydroavermectin B1b. In 2020, Ivermectin indicated that it was a good antiviral agent in the treatment of SARS-CoV-2 and a new mechanism of action has been suggested. Ivermectin would act on importin α/β heterodimer and affect nuclear transport and the translocation of viral proteins.

Fórmula: C₄₈H₇₄O₁₄

Pureza: Min. 90 Area-%

Cor e Forma: White Yellow Powder

Peso molecular: 875.09 g/mol

Ref: 3D-FI24744

Ivermectin (IVM), 95-102%

CAS: 70288-86-7

Fórmula: C₄₈H₇₄O₁₄

Pureza: min. 95 - 102%

Cor e Forma: White to off-white, Crystalline powder

Peso molecular: 875.10

Ref: SR-18443