EGFR
Os inibidores do receptor do fator de crescimento epidérmico (EGFR) são compostos que bloqueiam a sinalização do EGFR, um receptor frequentemente superexpresso em vários tipos de câncer e que desempenha um papel crucial na angiogênese. Os inibidores de EGFR são usados para prevenir o crescimento e a metástase de tumores, interrompendo as vias que promovem a formação de vasos sanguíneos nos tumores. Esses inibidores são amplamente utilizados na pesquisa e terapia do câncer. Na CymitQuimica, oferecemos uma seleção diversificada de inibidores de EGFR de alta qualidade para apoiar sua pesquisa em oncologia e angiogênese.
Foram encontrados 595 produtos para "EGFR".
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Tyrphostin A23
CAS:Fórmula:C10H6N2O2Pureza:>98.0%(GC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:186.17Tyrphostin AG528
CAS:Fórmula:C18H14N2O3Pureza:>97.0%(HPLC)Cor e Forma:Light yellow to Amber to Dark green powder to crystalPeso molecular:306.32Curcumin (Synthetic)
CAS:Fórmula:C21H20O6Pureza:>97.0%(T)Cor e Forma:Light yellow to Brown powder to crystalPeso molecular:368.39Tyrphostin A1
CAS:Fórmula:C11H8N2OPureza:>98.0%(GC)Cor e Forma:Light orange to Yellow to Green powder to crystalPeso molecular:184.20Butein
CAS:Fórmula:C15H12O5Pureza:>98.0%(HPLC)Cor e Forma:Light yellow to Brown powder to crystalPeso molecular:272.26Methyl 2,5-Dihydroxycinnamate
CAS:Fórmula:C10H10O4Pureza:>96.0%(HPLC)Cor e Forma:White to Yellow powder to crystalPeso molecular:194.19Curcumin (Natural)
CAS:Fórmula:C21H20O6Cor e Forma:Light yellow to Brown powder to crystalPeso molecular:368.39Neratinib
CAS:Fórmula:C30H29ClN6O3Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:557.05Gefitinib
CAS:Fórmula:C22H24ClFN4O3Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:446.91Tyrphostin AG 835
CAS:Fórmula:C18H16N2O3Pureza:>98.0%(HPLC)Cor e Forma:Light yellow to Amber to Dark green powder to crystalPeso molecular:308.34Erlotinib Hydrochloride
CAS:Fórmula:C22H23N3O4·HClPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:429.90PD 153035 Hydrochloride
CAS:Fórmula:C16H14BrN3O2·HClPureza:>97.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:396.67Lapatinib
CAS:Fórmula:C29H26ClFN4O4SPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:581.06Genistein
CAS:Fórmula:C15H10O5Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:270.24Lapatinib Ditosylate
CAS:Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:925.46Pelitinib
CAS:Fórmula:C24H23ClFN5O2Pureza:>97.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:467.93Erlotinib
CAS:Fórmula:C22H23N3O4Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:393.442-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]-
CAS:Fórmula:C18H13BrN4OPureza:98%Cor e Forma:SolidPeso molecular:381.2260Panitumumab
CAS:Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).Pureza:95% - 98.1% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:144.31 kDaEpertinib hydrochloride
CAS:Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity.Fórmula:C30H28Cl2FN5O3Pureza:99.14%Cor e Forma:SolidPeso molecular:596.48Ref: TM-T11213
1mg87,00€5mg178,00€1mL*10mM (DMSO)241,00€10mg295,00€25mg505,00€50mg715,00€100mg964,00€500mg1.935,00€Khellin
CAS:Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.Fórmula:C14H12O5Pureza:99.89% - 99.95%Cor e Forma:SolidPeso molecular:260.24LCH-7749944
CAS:LCH-7749944 suppresses human gastric cancer cell growth, induces apoptosis, and inhibits PAK4 with IC50 of 14.93 μM.Fórmula:C20H22N4O2Pureza:99.48%Cor e Forma:SolidPeso molecular:350.41Lapatinib
CAS:Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.Fórmula:C29H26ClFN4O4SPureza:99.00% - 99.81%Cor e Forma:SolidPeso molecular:581.06Rociletinib
CAS:Rociletinib (CNX-419) is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplasticFórmula:C27H28F3N7O3Pureza:98.52% - 99.25%Cor e Forma:SolidPeso molecular:555.55Pyrotinib dimaleate
CAS:Pyrotinib dimaleate is a selective EGFR/HER2 dual inhibitor, respectively, for the treatment of HER2-positive breast cancer.Cost-effective and quality-assured.Fórmula:C40H39ClN6O11Pureza:97.27% - 99.52%Cor e Forma:SolidPeso molecular:815.22Ref: TM-T12594
1mg146,00€5mg434,00€10mg577,00€1mL*10mM (DMSO)587,00€25mg897,00€50mg1.234,00€100mg1.665,00€Mutated EGFR-IN-1
CAS:Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activatingFórmula:C25H31N7OPureza:98.91%Cor e Forma:White SolidPeso molecular:445.56AZ7550 hydrochloride
CAS:AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Fórmula:C27H32ClN7O2Pureza:99.65%Cor e Forma:SolidPeso molecular:522.04Lapatinib ditosylate monohydrate
CAS:Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.Fórmula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPureza:98% - 99.41%Cor e Forma:White SolidPeso molecular:943.47Losatuxizumab
CAS:Losatuxizumab (ABT-806) is an anti-EGFR monoclonal antibody with potential anti-tumor activity for the study of advanced malignant solid tumors.Pureza:97.3% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.3% (SDS-PAGE); 95.1% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:144.85 kDa1-[4-[4-[[2-[(1E)-2-[4-(Trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole
CAS:Fórmula:C25H23F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:468.4709Barecetamab
CAS:Barecetamab (ISU-104) is a humanized monoclonal antibody against tyrosine protein kinase ErbB3 with anticancer activity.Pureza:97.1% (SDS-PAGE); 96.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 96.4% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:143.86 kDaErlotinib hydrochloride
CAS:Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Fórmula:C22H23N3O4·HClPureza:99.78% - 99.97%Cor e Forma:SolidPeso molecular:429.90Intetumumab
CAS:Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for xenograft tumor-bearing mice.Pureza:97.6% (SDS-PAGE); 97.1% (SEC-HPLC) - 97.6% (SDS-PAGE); 97.1% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:145.56 kDaAV-412
CAS:AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).Fórmula:C41H44ClFN6O7S2Pureza:99.85% - 99.92%Cor e Forma:SolidPeso molecular:851.41Ref: TM-T10419
1mg42,00€2mg55,00€5mg90,00€1mL*10mM (DMSO)129,00€10mg137,00€25mg240,00€50mg403,00€100mg582,00€HyT36
CAS:HyT36: hydrophobic tag that destabilizes fusion proteins & Her3 pseudokinase; treats cells with acute erht.Fórmula:C25H44ClNO3Pureza:99.02%Cor e Forma:SolidPeso molecular:442.07Ref: TM-T72075
1mg52,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg178,00€25mg371,00€50mg595,00€100mg860,00€Erlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Fórmula:C22H23N3O4Pureza:98.19% - 99.98%Cor e Forma:White SolidPeso molecular:393.44BLU-945
CAS:BLU-945 is a reversible, potent, highly selective, and orally available epidermal growth factor receptor tyrosine kinase inhibitor (TKIs).Cost-effective and quality-assured.Fórmula:C28H37FN6O3SPureza:99.11% - 99.16%Cor e Forma:SolidPeso molecular:556.7Ref: TM-T9754
1mg35,00€5mg75,00€1mL*10mM (DMSO)93,00€10mg114,00€25mg222,00€50mg356,00€100mg557,00€200mg790,00€Propanedinitrile,2-[(4-methoxyphenyl)methylene]-
CAS:Fórmula:C11H8N2OPureza:98%Cor e Forma:SolidPeso molecular:184.1940O-Desmethyl gefitinib
CAS:O-Desmethyl gefitinib is an active EGFR inhibitor (IC50: 36 nM), a metabolite of Gefitinib, formed by CYP2D6.Fórmula:C21H22ClFN4O3Pureza:97.17%Cor e Forma:White SolidPeso molecular:432.88Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:99.41%Cor e Forma:White SolidPeso molecular:925.46(2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]-2-propenamide
CAS:Fórmula:C18H16N2O3Pureza:97%Cor e Forma:SolidPeso molecular:308.3312Mevastatin
CAS:Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Fórmula:C23H34O5Pureza:99.12%Cor e Forma:SolidPeso molecular:390.51Gancotamab
CAS:Gancotamab (MM-302) is a polyethylene glycolated liposome targeting HER2 with antitumor activity for the study of advanced HER2-positive breast cancer.Pureza:96.7% (SDS-PAGE); 98.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 98.4% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:25.79 kDaPetosemtamab
CAS:Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR & LGR5, used in solid tumor research like HNSCC & CRC.Pureza:> 95% - > 95%Cor e Forma:Transparent LiquidPeso molecular:145.97 kDaAllitinib
CAS:Allitinib (AST-1306) (AST-1306) has anti-cancer activity，and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1]Fórmula:C24H18ClFN4O2Pureza:99.89% - 99.91%Cor e Forma:Yellow SolidPeso molecular:448.88Ref: TM-T14336
1mg50,00€5mg105,00€1mL*10mM (DMSO)128,00€10mg172,00€25mg313,00€50mg467,00€100mg663,00€Margetuximab
CAS:Margetuximab (MGAH-22) is a second generation anti-HER2 monoclonal antibody with anti-tumor activity.Pureza:95.3% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.3% (SDS-PAGE); 99.3% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:145.86 kDaGefitinib
CAS:Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations.Fórmula:C22H24ClFN4O3Pureza:99.92% - >99.99%Cor e Forma:White SolidPeso molecular:446.90
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