p53
Os inibidores de p53 têm como alvo a proteína p53, um supressor tumoral que desempenha um papel crucial na regulação do ciclo celular, reparo de DNA e apoptose. Embora o p53 seja frequentemente mutado ou inativado em células cancerígenas, sua inibição às vezes é necessária para proteger as células saudáveis da apoptose durante certos tratamentos. Por outro lado, restaurar a função do p53 em tumores pode levar à apoptose das células cancerígenas. A pesquisa sobre inibidores de p53 é complexa e significativa para compreender os mecanismos do câncer e desenvolver novas terapias. Na CymitQuimica, oferecemos uma seleção de inibidores e moduladores de p53 de alta qualidade para apoiar sua pesquisa em biologia do câncer, apoptose e desenvolvimento terapêutico.
Foram encontrados 63 produtos de "p53"
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Amifostine
CAS:Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.Fórmula:C5H15N2O3PSPureza:99.59%Cor e Forma:White SolidPeso molecular:214.22Quinacrine dihydrochloride
CAS:Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplasticFórmula:C23H30CLN3O·2HClPureza:98.24% - 99.80%Cor e Forma:Yellow Crystals Or PowderPeso molecular:472.88MT 63-78
CAS:MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).
Fórmula:C21H14N2O2Pureza:97.11%Cor e Forma:SolidPeso molecular:326.35NSC-87877
CAS:NSC-87877 inhibits Shp2 (IC50=0.318μM), Shp1 (IC50=0.355μM), and DUSP26 phosphatases.Fórmula:C19H13N3O7S2Pureza:97.35%Cor e Forma:SolidPeso molecular:459.45Etoposide
CAS:Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).
Fórmula:C29H32O13Pureza:99.19% - 99.94%Cor e Forma:Crystals From Methanol SolidPeso molecular:588.56Chlorambucil
CAS:Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard.Fórmula:C14H19Cl2NO2Pureza:97.37% - 98.45%Cor e Forma:Off-White Slightly Granular Powder Melting Point 65-69°CPeso molecular:304.21Unesbulin
CAS:Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).
Fórmula:C19H13F5N6Pureza:98.71%Cor e Forma:SolidPeso molecular:420.34Transcription Factor-Targeted Compound Library
Well-chosen xnum compounds with unique structures targeting transcription factor;Cor e Forma:Odour SolidRef: TM-L1380
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarApoptosis Compound Library
A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;Cor e Forma:Odour SolidRef: TM-L9000
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarTetrofosmin
CAS:Tetrofosmin is a phosphine developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds.Fórmula:C18H40O4P2Cor e Forma:SolidPeso molecular:382.46p53 (17-26)
CAS:Peptide is p53's amino acids 17-26, contacts Mdm-2 binding domain, also called p53N.Fórmula:C60H90N12O17Pureza:98%Cor e Forma:SolidPeso molecular:1251.43UNC 0631
CAS:UNC 0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).Fórmula:C37H61N7O2Pureza:97.42%Cor e Forma:SolidPeso molecular:635.93ReACp53 acetate
ReACp53 acetate could inhibit p53 amyloid formation and rescue p53 function in cancer cell lines.Fórmula:C110H210N52O26Pureza:99.55%Cor e Forma:SolidPeso molecular:2677.18BMH-7 HCl
BMH-7 HCl is a p53 activator, showing anti-cancer activity by activating the p53 pathway.Fórmula:C20H22ClN5OPureza:99.62%Cor e Forma:SolidPeso molecular:383.88Anti-p53 Antibody (9G324)
Anti-p53 Antibody (9G324) is an antibody targeting p53. Anti-p53 Antibody (9G324) can be used in ELISA, IF.Cor e Forma:Odour LiquidAnti-p53 Antibody (8C308)
Anti-p53 Antibody (8C308) is an antibody targeting p53. Anti-p53 Antibody (8C308) can be used in ELISA, WB, IF, FCM.Cor e Forma:Odour LiquidAnti-p53 Antibody (9G129)
Anti-p53 Antibody (9G129) is a Rabbit antibody targeting p53. Anti-p53 Antibody (9G129) can be used in IHC-P,ICC/IF.Cor e Forma:Odour LiquidAnti-Phospho-TP53 (Ser33) Antibody (4K787)
Anti-Phospho-TP53 (Ser33) Antibody (4K787) is an antibody targeting Phospho-TP53 (Ser33). Anti-Phospho-TP53 (Ser33) Antibody (4K787) can be used in ELISA, IHC, IF.Cor e Forma:Odour LiquidAnti-p53 Antibody (2V863)
Anti-p53 Antibody (2V863) is a Mouse antibody targeting p53. Anti-p53 Antibody (2V863) can be used in ELISA,ELISA(Det).Cor e Forma:Odour LiquidAnti-p53 Antibody (3K688)
Anti-p53 Antibody (3K688) is a Rabbit antibody targeting p53. Anti-p53 Antibody (3K688) can be used in WB,ELISA,IP.Cor e Forma:Odour Liquid
