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Caspase

Caspase

Os inibidores de caspases são compostos que bloqueiam a atividade das caspases, uma família de proteases que são executores centrais da apoptose. As caspases clivam substratos específicos dentro da célula para desencadear o processo apoptótico, levando à morte celular programada. Os inibidores de caspases são usados para estudar os mecanismos da apoptose, bem como para prevenir a morte celular indesejada em vários modelos de pesquisa. Esses inibidores também são explorados em contextos terapêuticos para proteger as células da apoptose em doenças como a neurodegeneração. Na CymitQuimica, oferecemos uma ampla gama de inibidores de caspases de alta qualidade para apoiar sua pesquisa em apoptose, morte celular e áreas relacionadas.

Foram encontrados 125 produtos de "Caspase"

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  • Aspirin

    CAS:
    <p>Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.</p>
    Fórmula:C9H8O4
    Pureza:99.78% - 99.91%
    Cor e Forma:White Solid Crystalline
    Peso molecular:180.16
  • Q-VD-OPH

    CAS:
    <p>Q-VD-OPh is an irreversible caspase inhibitor with an IC50 value of 48 nM against caspase-7 and between 25 and 400 nM against caspase-1, 3, 8, 9, 10, 12.</p>
    Fórmula:C26H25F2N3O6
    Pureza:97.8% - 98.95%
    Cor e Forma:Solid
    Peso molecular:513.5
  • Thiabendazole

    CAS:
    <p>Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.</p>
    Fórmula:C10H7N3S
    Pureza:99.14%
    Cor e Forma:Light Yellow Powder
    Peso molecular:201.25
  • Fenbufen

    CAS:
    <p>Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.</p>
    Fórmula:C16H14O3
    Pureza:98.35% - 98.46%
    Cor e Forma:White Solid
    Peso molecular:254.28
  • Diclofenac sodium

    CAS:
    <p>Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.</p>
    Fórmula:C14H10Cl2NNaO2
    Pureza:98.21% - 99.73%
    Cor e Forma:White Or Off-White Powder
    Peso molecular:318.13
  • Ac-FLTD-CMK

    CAS:
    <p>Ac-FLTD-CMK, an abscisicin D derivative, selectively inhibits inflammatory caspases-1, -4, and -11 (IC50: 46.7 nM, 1.49 μM, 329 nM) but not caspase-3.</p>
    Fórmula:C26H37ClN4O8
    Pureza:95.17%
    Cor e Forma:Solid
    Peso molecular:569.05
  • Dehydrocorydaline chloride

    CAS:
    <p>Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.</p>
    Fórmula:C22H24ClNO4
    Pureza:99.53%
    Cor e Forma:Solid
    Peso molecular:401.88
  • Ac-YVAD-CMK

    CAS:
    <p>Ac-YVAD-CMK: Irreversible Caspase-1 inhibitor; halts pyroptosis, IL-1β/IL-18; neuroprotective and anti-inflammatory.</p>
    Fórmula:C24H33ClN4O8
    Pureza:97.08% - 99.909%
    Cor e Forma:Solid
    Peso molecular:540.99
  • Lacidipine

    CAS:
    <p>Lacidipine (SN-305) is a slow-acting, long-duration lipophilic dihydropyridine calcium blocker that prevents reflex tachycardia and lowers blood pressure.</p>
    Fórmula:C26H33NO6
    Pureza:99.98%
    Cor e Forma:White-To-Off-White Crystalline Solid
    Peso molecular:455.54
  • Diclofenac diethylamine

    CAS:
    <p>Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).</p>
    Fórmula:C18H22Cl2N2O2
    Pureza:99.81% - 99.87%
    Cor e Forma:Solid
    Peso molecular:369.29
  • Diclofenac

    CAS:
    <p>Diclofenac: a nonsteroidal compound inhibiting COX-1 and COX-2, reducing pro-inflammatory prostaglandins.</p>
    Fórmula:C14H11Cl2NO2
    Pureza:99.69% - 99.97%
    Cor e Forma:Crystals From Ether-Petroleum Ether Solid
    Peso molecular:296.15
  • Terfenadine

    CAS:
    <p>Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.</p>
    Fórmula:C32H41NO2
    Pureza:98.76% - 99.75%
    Cor e Forma:Solid
    Peso molecular:471.67
  • ML-9

    CAS:
    <p>ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.</p>
    Fórmula:C15H18Cl2N2O2S
    Pureza:99.69%
    Cor e Forma:Crystalline Solid
    Peso molecular:361.29
  • Oxidopamine hydrochloride

    CAS:
    <p>Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.</p>
    Fórmula:C8H12ClNO3
    Pureza:98.34% - 99.85%
    Cor e Forma:Physical Description Beige Solid (Ntp 1992)
    Peso molecular:205.64
  • Oxidopamine hydrobromide

    CAS:
    <p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>
    Fórmula:C8H12BrNO3
    Pureza:98.22% - 99.88%
    Cor e Forma:Beige To Brown Fine Crystalline Powder
    Peso molecular:250.09
  • Crustecdysone

    CAS:
    <p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>
    Fórmula:C27H44O7
    Pureza:99.06% - 99.67%
    Cor e Forma:Canary Yellow Fine Powder
    Peso molecular:480.63
  • Caspase-3 activator 2


    <p>Caspase-3 Activator 2 (Compound 2f) is a caspase 3 activator with cytotoxic effects on HL-60 and K562 cells, exhibiting IC 50 values of 33.52 μM and 76.90 μM,</p>
    Pureza:98%
    Cor e Forma:Odour Solid
  • Z-VDVA-(DL-Asp)-FMK

    CAS:
    <p>Z-VDVA-(DL-Asp)-FMK is a derivative compound of Z-VDVAD-FMK specifically designed as an inhibitor targeting caspase-2.</p>
    Fórmula:C32H46FN5O11
    Cor e Forma:Solid
    Peso molecular:695.742
  • PQ401

    CAS:
    <p>PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50&lt;1 μM).</p>
    Fórmula:C18H16ClN3O2
    Pureza:99.77%
    Cor e Forma:Solid
    Peso molecular:341.79
  • Protease Inhibitor Library


    <p>A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;</p>
    Cor e Forma:Odour Solid
  • BOC-D-FMK

    CAS:
    <p>Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).</p>
    Fórmula:C11H18FNO5
    Pureza:97.02%
    Cor e Forma:Solid
    Peso molecular:263.26
  • (Iso)-Z-VAD(OMe)-FMK

    CAS:
    <p>(Iso)-Z-VAD(OMe)-FMK is an isomer of Z-VAD(OMe)-FMK, which is a pan-caspase inhibitor with irreversible properties. Z-VAD(OMe)-FMK is also an inhibitor UCHL1.</p>
    Fórmula:C22H30FN3O7
    Pureza:97.10%
    Cor e Forma:Soild
    Peso molecular:467.49
  • Apoptosis Compound Library


    <p>A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;</p>
    Cor e Forma:Odour Solid
  • Sanggenon G

    CAS:
    <p>Sanggenon G inhibits XIAP by binding its BIR3 domain; affinity is 34.26 μM, boosting caspase activation.</p>
    Fórmula:C40H38O11
    Cor e Forma:Solid
    Peso molecular:694.72
  • Sarglaroids F


    <p>Sarglaroids F (compound 6), an anti-inflammatory agent extracted from the roots of Grass Coral, suppresses LPS/ATP-induced IL-1β secretion by modulating K+</p>
    Fórmula:C38H44O12
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:692.75
  • TNF-α-IN-11


    <p>TNF-α-IN-11 (Compound 10) is a TNF-α inhibitor exhibiting a dissociation constant (K D) of 12.06 μM.</p>
    Fórmula:C24H26N2O5
    Cor e Forma:Solid
    Peso molecular:422.47
  • Ac-VDVAD-CHO TFA


    <p>Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor with IC50 values of 46 nM and 15 nM, respectively.</p>
    Cor e Forma:Odour Solid
  • Ac-Trp-Glu-His-Asp-Aldehyde

    CAS:
    <p>Ac-Trp-Glu-His-Asp-Aldehyde is a powerful and selective inhibitor of caspase-1, demonstrating a K_i value of 56 pM [1] [2].</p>
    Fórmula:C28H33N7O9
    Cor e Forma:Solid
    Peso molecular:611.6
  • IRF1-IN-2

    CAS:
    <p>IRF1-IN-2 is a small molecule IRF1 inhibitor that suppresses pyroptosis, protecting against radiation-induced skin damage.</p>
    Fórmula:C18H20N2O4S
    Pureza:99.85%
    Cor e Forma:Solid
    Peso molecular:360.43
  • Ac-LEHD-AMC

    CAS:
    <p>Ac-LEHD-AMC, a fluorogenic caspase-9 substrate, releases fluorescent AMC upon cleavage, aiding caspase-9 activity measurement.</p>
    Fórmula:C33H41N7O11
    Cor e Forma:Solid
    Peso molecular:711.729
  • Reproxalap

    CAS:
    <p>Reproxalap (NS-2) is a dry eye treatment that neutralizes aldehydes like malondialdehyde.</p>
    Fórmula:C12H13ClN2O
    Pureza:99.4% - 99.97%
    Cor e Forma:Solid
    Peso molecular:236.7
  • Ac-LEVD-CHO

    CAS:
    <p>Ac-LEVD-CHO, a caspase-4 inhibitor, is a peptide with the sequence Ac-Leu-Glu-Val-Asp-al [1].</p>
    Fórmula:C22H36N4O9
    Cor e Forma:Solid
    Peso molecular:500.54
  • Boc-Asp(OBzl)-CMK

    CAS:
    <p>Boc-Asp(OBzl)-CMK, an inhibitor of IL-1 converting enzyme (ICE, caspase1), prevents the death of CHP100 neuroblastoma cells and inhibits IL-1β release induced by the viral coat protein [1].</p>
    Fórmula:C17H22ClNO5
    Cor e Forma:Solid
    Peso molecular:355.81
  • δ-secretase inhibitor 11

    CAS:
    <p>δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.</p>
    Fórmula:C10H12N4O2
    Pureza:99.84%
    Cor e Forma:Solid
    Peso molecular:220.23
  • Pralnacasan

    CAS:
    <p>Pralnacasan blocks IL-18, IL-1β, IFN-γ. It’s a potent oral enzyme inhibitor with use in arthritis therapy (Ki: 1.4 nM).</p>
    Fórmula:C26H29N5O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:523.54
  • Z-WEHD-FMK

    CAS:
    <p>Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6 μM).</p>
    Fórmula:C37H42FN7O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:763.78
  • Ac-IEPD-AFC

    CAS:
    <p>Ac-IEPD-AFC (IEPD) is a fluorescent substrate for granzyme B and can be used to measure granzyme B activity.</p>
    Fórmula:C32H38F3N5O11
    Pureza:99.16%
    Cor e Forma:Solid
    Peso molecular:725.67
  • IRF1-IN-1

    CAS:
    <p>IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor , inhibiting the cleavage of Caspase 1, GSDMD, IL-1, and PARP1,protecting against skin inflammatory damage.</p>
    Fórmula:C22H24N4O4S
    Pureza:99.88%
    Cor e Forma:Solid
    Peso molecular:440.52
  • AKN-028

    CAS:
    <p>AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.</p>
    Fórmula:C17H14N6
    Pureza:99.88%
    Cor e Forma:Solid
    Peso molecular:302.33
  • TD1092


    <p>TD1092, a pan-IAP degrader, activates caspase 3/7, induces apoptosis in cancer cells, inhibits NF-κB, and is used in cancer research.</p>
    Fórmula:C55H70N8O9
    Cor e Forma:Solid
    Peso molecular:987.19
  • MX1013

    CAS:
    <p>MX1013, a dipeptide pan-caspase inhibitor, inhibits caspase-1, -3, -6, -7, -8, and -9.</p>
    Fórmula:C18H23FN2O6
    Cor e Forma:Solid
    Peso molecular:382.39
  • Almorexant hydrochloride

    CAS:
    <p>Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.</p>
    Fórmula:C29H32ClF3N2O3
    Pureza:99.85%
    Cor e Forma:Solid
    Peso molecular:549.02
  • J22352

    CAS:
    <p>J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects in</p>
    Fórmula:C24H21N3O4
    Cor e Forma:Solid
    Peso molecular:415.44
  • EF24

    CAS:
    <p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>
    Fórmula:C19H15F2NO
    Pureza:99.71%
    Cor e Forma:Solid
    Peso molecular:311.33
  • PAC-1

    CAS:
    <p>PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.</p>
    Fórmula:C23H28N4O2
    Pureza:96.78% - 99.77%
    Cor e Forma:Solid
    Peso molecular:392.49
  • Ivachtin

    CAS:
    <p>Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining</p>
    Fórmula:C20H21N3O7S
    Pureza:99.74%
    Cor e Forma:Solid
    Peso molecular:447.46
  • Penicillic acid

    CAS:
    <p>Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.</p>
    Fórmula:C8H10O4
    Pureza:98%
    Cor e Forma:Needles From Petroleum Ether Slight Yellow Powder
    Peso molecular:170.16
  • Guggulsterone

    CAS:
    <p>Guggulsterone (Guggulsterone E&amp;Z) E&amp;Z is a 3-hydroxy steroid. It has a role as an androgen.</p>
    Fórmula:C21H28O2
    Pureza:99.4% - 99.8%
    Cor e Forma:Light Yellow Powder
    Peso molecular:312.45
  • 5,​7,​4'-​Trimethoxyflavone

    CAS:
    <p>5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.</p>
    Fórmula:C18H16O5
    Pureza:97.53%
    Cor e Forma:Solid
    Peso molecular:312.32
  • Chelidonic acid

    CAS:
    <p>Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.</p>
    Fórmula:C7H4O6
    Pureza:99.03%
    Cor e Forma:Solid
    Peso molecular:184.1
  • Almorexant

    CAS:
    <p>Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.</p>
    Fórmula:C29H31F3N2O3
    Pureza:97.75% - 98.02%
    Cor e Forma:Solid
    Peso molecular:512.56
  • Asperosaponin VI

    CAS:
    <p>Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.</p>
    Fórmula:C47H76O18
    Pureza:97.15% - 99.79%
    Cor e Forma:Solid
    Peso molecular:929.1
  • Z-IETD-FMK

    CAS:
    <p>Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.</p>
    Fórmula:C30H43FN4O11
    Pureza:95% - 99.81%
    Cor e Forma:Solid
    Peso molecular:654.68
  • Ginsenoside Rh2

    CAS:
    <p>Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.</p>
    Fórmula:C36H62O8
    Pureza:99.20% - 99.76%
    Cor e Forma:White Powder
    Peso molecular:622.87
  • 2-HBA

    CAS:
    <p>2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.</p>
    Fórmula:C17H14O3
    Pureza:99.76%
    Cor e Forma:Solid
    Peso molecular:266.29
  • Ac-DEVD-AMC

    CAS:
    <p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>
    Fórmula:C30H37N5O13
    Pureza:98.20%
    Cor e Forma:White Powder
    Peso molecular:675.64
  • KEA1-97

    CAS:
    <p>Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).</p>
    Fórmula:C15H9Cl2FN4
    Pureza:97.07%
    Cor e Forma:Solid
    Peso molecular:335.16
  • Paris saponin VII

    CAS:
    <p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>
    Fórmula:C51H82O21
    Pureza:99.51% - 99.63%
    Cor e Forma:Solid
    Peso molecular:1031.18
  • Z-VAD(OMe)-FMK

    CAS:
    <p>View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.</p>
    Fórmula:C22H30FN3O7
    Pureza:95.92% - 99.71%
    Cor e Forma:Solid
    Peso molecular:467.49
  • Ac-DEVD-CHO acetate


    <p>Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.</p>
    Fórmula:C22H34N4O13
    Pureza:98.54%
    Cor e Forma:Solid
    Peso molecular:562.52
  • PHYTOSPHINGOSINE

    CAS:
    <p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>
    Fórmula:C18H39NO3
    Pureza:99.81%
    Cor e Forma:Solid
    Peso molecular:317.51
  • TC11

    CAS:
    <p>TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis</p>
    Fórmula:C20H22N2O2
    Pureza:97.86%
    Cor e Forma:Solid
    Peso molecular:322.4
  • Belnacasan

    CAS:
    <p>Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.</p>
    Fórmula:C24H33ClN4O6
    Pureza:96.53% - 99.5%
    Cor e Forma:Solid
    Peso molecular:508.99
  • Sesamolin

    CAS:
    <p>Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.</p>
    Fórmula:C20H18O7
    Pureza:98.77% - 99.04%
    Cor e Forma:Solid
    Peso molecular:370.35
  • Wedelolactone

    CAS:
    <p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>
    Fórmula:C16H10O7
    Pureza:98.07% - 99.87%
    Cor e Forma:Solid
    Peso molecular:314.25
  • PI-1840

    CAS:
    <p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>
    Fórmula:C22H26N4O3
    Pureza:98.82%
    Cor e Forma:Solid
    Peso molecular:394.47
  • Dehydrocorydaline

    CAS:
    <p>1.</p>
    Fórmula:C22H24NO4
    Pureza:99.84%
    Cor e Forma:Solid
    Peso molecular:366.43
  • Daphnetin

    CAS:
    <p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>
    Fórmula:C9H6O4
    Pureza:97.47% - 99.8%
    Cor e Forma:Solid
    Peso molecular:178.14
  • Ac-DEVD-pNA

    CAS:
    <p>Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.</p>
    Fórmula:C26H34N6O13
    Pureza:>99.99%
    Cor e Forma:White
    Peso molecular:638.58
  • Z-YVAD-FMK

    CAS:
    <p>AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.</p>
    Fórmula:C31H39FN4O9
    Pureza:98.00%
    Cor e Forma:Solid
    Peso molecular:630.66
  • Emricasan

    CAS:
    <p>Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.</p>
    Fórmula:C26H27F4N3O7
    Pureza:98.13% - 99%
    Cor e Forma:Solid
    Peso molecular:569.5
  • Z-FA-FMK

    CAS:
    <p>Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.</p>
    Fórmula:C21H23FN2O4
    Pureza:98.84% - 99.68%
    Cor e Forma:Solid
    Peso molecular:386.42
  • Dihydrocapsaicin

    CAS:
    <p>Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.</p>
    Fórmula:C18H29NO3
    Pureza:99.61% - ≥95%
    Cor e Forma:White Crystal
    Peso molecular:307.43
  • Aristolactam I

    CAS:
    <p>Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.</p>
    Fórmula:C17H11NO4
    Pureza:98.98% - 99.63%
    Cor e Forma:Solid
    Peso molecular:293.27
  • Ossirene

    CAS:
    <p>Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.</p>
    Fórmula:C2H4Cl3O2Te·H4N
    Pureza:≥98%
    Cor e Forma:Solid
    Peso molecular:312.05
  • Tauroursodeoxycholate

    CAS:
    <p>Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.</p>
    Fórmula:C26H45NO6S
    Pureza:98.77% - 99.93%
    Cor e Forma:White Solid
    Peso molecular:499.7
  • Senkyunolide I

    CAS:
    <p>1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.</p>
    Fórmula:C12H16O4
    Pureza:99.73% - 99.88%
    Cor e Forma:Solid
    Peso molecular:224.25
  • Diclofenac Potassium

    CAS:
    <p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>
    Fórmula:C14H10Cl2KNO2
    Pureza:99.51%
    Cor e Forma:White To Yellowish Crystalline Powder
    Peso molecular:334.24
  • CASP3 Activator 1541

    CAS:
    <p>CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.</p>
    Fórmula:C24H17N3O4
    Pureza:98.84%
    Cor e Forma:Solid
    Peso molecular:411.41
  • L67

    CAS:
    <p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>
    Fórmula:C16H14Br2N4O4
    Pureza:98.34% - 99.56%
    Cor e Forma:Solid
    Peso molecular:486.11
  • Phenoxodiol

    CAS:
    <p>Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)</p>
    Fórmula:C15H12O3
    Pureza:98.07%
    Cor e Forma:Solid
    Peso molecular:240.25
  • AVN-944

    CAS:
    <p>AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.</p>
    Fórmula:C25H27N5O5
    Pureza:99.07% - ≥95%
    Cor e Forma:Solid
    Peso molecular:477.51
  • Taurodeoxycholic acid sodium hydrate

    CAS:
    <p>Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.</p>
    Fórmula:C26H46NNaO7S
    Pureza:99.95%
    Cor e Forma:Solid
    Peso molecular:539.70
  • 5,7-Dihydroxychromone

    CAS:
    <p>1.</p>
    Fórmula:C9H6O4
    Pureza:99.76% - ≥95%
    Cor e Forma:Solid
    Peso molecular:178.14
  • Boc-Asp(OMe)-fluoromethyl ketone

    CAS:
    <p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>
    Fórmula:C11H18FNO5
    Pureza:≥98%
    Cor e Forma:Solid
    Peso molecular:263.26
  • Tauroursodeoxycholate sodium

    CAS:
    <p>Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.</p>
    Fórmula:C26H44NNaO6S
    Pureza:97.90%
    Cor e Forma:Solid
    Peso molecular:521.69
  • Z-VAD-FMK

    CAS:
    <p>Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not</p>
    Fórmula:C21H28FN3O7
    Pureza:98.24% - 99.79%
    Cor e Forma:Solid
    Peso molecular:453.46
  • (E/Z)-Necrosulfonamide

    CAS:
    <p>(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.</p>
    Fórmula:C18H15N5O6S2
    Pureza:97.62% - 98%
    Cor e Forma:Solid
    Peso molecular:461.47
  • Lobaplatin

    CAS:
    <p>Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.</p>
    Fórmula:C9H18N2O3Pt
    Pureza:98.00%
    Cor e Forma:Solid
    Peso molecular:397.33
  • Z-DEVD-FMK

    CAS:
    <p>Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,</p>
    Fórmula:C30H41FN4O12
    Pureza:96.19% - 99.69%
    Cor e Forma:Solid
    Peso molecular:668.66
  • Arnicolide D

    CAS:
    <p>Arnicolide D is a sesquiterpene lactone.</p>
    Fórmula:C19H24O5
    Pureza:96.66%
    Cor e Forma:Solid
    Peso molecular:332.39
  • Dehydrocorydaline nitrate

    CAS:
    <p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>
    Fórmula:C22H24N2O7
    Pureza:99.79% - 99.92%
    Cor e Forma:Solid
    Peso molecular:428.44
  • Dehydrotrametenolic acid

    CAS:
    <p>Dehydrotrametenolic acid (Dehydroeburicoic acid) induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in</p>
    Fórmula:C31H48O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:468.71
  • Limonin glucoside

    CAS:
    <p>Limonin glucoside: a citrus compound, blocks HIV/HTLV-1, triggers cancer cell death, kills Aedes larvae.</p>
    Fórmula:C32H42O14
    Cor e Forma:Solid
    Peso molecular:650.674
  • Caspase-3-IN-1

    CAS:
    <p>Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).</p>
    Fórmula:C26H25N3O6S
    Cor e Forma:Solid
    Peso molecular:507.56
  • Tigilanol tiglate

    CAS:
    <p>Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.</p>
    Fórmula:C30H42O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:562.65
  • Anisperimus

    CAS:
    <p>Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.</p>
    Fórmula:C18H39N7O3
    Pureza:98.10%
    Cor e Forma:Solid
    Peso molecular:401.55
  • AD-2646

    CAS:
    <p>AD-2646 has antidepressant activity and inhibits 2-deoxy-D-glucose (2-DG)-induced gastric acid secretion.</p>
    Fórmula:C23H40N2O4
    Cor e Forma:Solid
    Peso molecular:408.57
  • ZYZ-488

    CAS:
    <p>ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.</p>
    Fórmula:C20H29N3O11
    Pureza:99.04%
    Cor e Forma:Solid
    Peso molecular:487.46
  • Caspase-9 Inhibitor III

    CAS:
    <p>Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.</p>
    Fórmula:C24H35ClN6O9
    Cor e Forma:Solid
    Peso molecular:587.02