Caspase
Os inibidores de caspases são compostos que bloqueiam a atividade das caspases, uma família de proteases que são executores centrais da apoptose. As caspases clivam substratos específicos dentro da célula para desencadear o processo apoptótico, levando à morte celular programada. Os inibidores de caspases são usados para estudar os mecanismos da apoptose, bem como para prevenir a morte celular indesejada em vários modelos de pesquisa. Esses inibidores também são explorados em contextos terapêuticos para proteger as células da apoptose em doenças como a neurodegeneração. Na CymitQuimica, oferecemos uma ampla gama de inibidores de caspases de alta qualidade para apoiar sua pesquisa em apoptose, morte celular e áreas relacionadas.
Foram encontrados 163 produtos para "Caspase".
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Ac-AAVALLPAVLLALLAP-YVAD-CHO
CAS:Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable inhibitor of caspase-1 exhibiting antitumor activity [1].Fórmula:C97H160N20O24Pureza:98%Cor e Forma:SolidPeso molecular:1990.43Reproxalap
CAS:Reproxalap (NS-2) is a dry eye treatment that neutralizes aldehydes like malondialdehyde.Fórmula:C12H13ClN2OPureza:99.4% - 99.97%Cor e Forma:SolidPeso molecular:236.7Tripeptide-32
CAS:Tripeptide-32 is a bioactive peptide recognized for its anti-aging properties, commonly utilized as an ingredient in cosmetics [1].Fórmula:C12H22N4O5Pureza:98%Cor e Forma:SolidPeso molecular:302.33J22352
CAS:J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects inFórmula:C24H21N3O4Cor e Forma:SolidPeso molecular:415.44Almorexant hydrochloride
CAS:Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.Fórmula:C29H32ClF3N2O3Pureza:99.85%Cor e Forma:White SolidPeso molecular:549.02MX1013
CAS:MX1013, a dipeptide pan-caspase inhibitor, inhibits caspase-1, -3, -6, -7, -8, and -9.Fórmula:C18H23FN2O6Cor e Forma:SolidPeso molecular:382.39Phenoxodiol
CAS:Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)Fórmula:C15H12O3Pureza:98.07% - 99.18%Cor e Forma:White SolidPeso molecular:240.25Ref: TM-T16522
1mg63,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg353,00€50mg537,00€100mg767,00€KEA1-97
CAS:Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).Fórmula:C15H9Cl2FN4Pureza:97.07%Cor e Forma:Yellow SolidPeso molecular:335.16L67
CAS:L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).Fórmula:C16H14Br2N4O4Pureza:98.34% - 99.56%Cor e Forma:SolidPeso molecular:486.115,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Fórmula:C18H16O5Pureza:97.53%Cor e Forma:SolidPeso molecular:312.32Almorexant
CAS:Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.Fórmula:C29H31F3N2O3Pureza:97.75% - 98.02%Cor e Forma:SolidPeso molecular:512.56CASP3 Activator 1541
CAS:CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.Fórmula:C24H17N3O4Pureza:98.84%Cor e Forma:SolidPeso molecular:411.41Ref: TM-T8652
1mg34,00€5mg71,00€1mL*10mM (DMSO)86,00€10mg105,00€25mg215,00€50mg344,00€100mg532,00€200mg740,00€Diclofenac Potassium
CAS:Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.Fórmula:C14H10Cl2KNO2Pureza:99.93%Cor e Forma:White SolidPeso molecular:334.24Ac-DEVD-AMC
CAS:Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .Fórmula:C30H37N5O13Pureza:99.89%Cor e Forma:White PowderPeso molecular:675.64Belnacasan
CAS:Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.Fórmula:C24H33ClN4O6Pureza:96.53% - 99.5%Cor e Forma:SolidPeso molecular:508.99Ref: TM-T6090
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg81,00€25mg161,00€50mg222,00€100mg396,00€200mg585,00€Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Fórmula:C26H45NO6SPureza:98.77% - 99.93%Cor e Forma:White SolidPeso molecular:499.72-HBA
CAS:2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.Fórmula:C17H14O3Pureza:99.76%Cor e Forma:Red SolidPeso molecular:266.29Ref: TM-T7374
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg75,00€25mg137,00€50mg213,00€100mg340,00€200mg504,00€PAC-1
CAS:PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.Fórmula:C23H28N4O2Pureza:96.78% - 99.76%Cor e Forma:White SolidPeso molecular:392.49TC11
CAS:TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosisFórmula:C20H22N2O2Pureza:97.86%Cor e Forma:Yellow SolidPeso molecular:322.4Ginsenoside Rh2
CAS:Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.Fórmula:C36H62O8Pureza:99.20% - 99.76%Cor e Forma:White PowderPeso molecular:622.87
