Caspase
Os inibidores de caspases são compostos que bloqueiam a atividade das caspases, uma família de proteases que são executores centrais da apoptose. As caspases clivam substratos específicos dentro da célula para desencadear o processo apoptótico, levando à morte celular programada. Os inibidores de caspases são usados para estudar os mecanismos da apoptose, bem como para prevenir a morte celular indesejada em vários modelos de pesquisa. Esses inibidores também são explorados em contextos terapêuticos para proteger as células da apoptose em doenças como a neurodegeneração. Na CymitQuimica, oferecemos uma ampla gama de inibidores de caspases de alta qualidade para apoiar sua pesquisa em apoptose, morte celular e áreas relacionadas.
Foram encontrados 163 produtos para "Caspase".
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Ac-DEVD-pNA
CAS:Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.Fórmula:C26H34N6O13Pureza:>99.99%Cor e Forma:WhitePeso molecular:638.58Ref: TM-T7816
2mg34,00€5mg57,00€10mg75,00€1mL*10mM (DMSO)79,00€25mg160,00€50mg231,00€100mg335,00€200mg477,00€Z-YVAD-FMK
CAS:AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.Fórmula:C31H39FN4O9Pureza:98.00%Cor e Forma:White SolidPeso molecular:630.66Dihydrocapsaicin
CAS:Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.Fórmula:C18H29NO3Pureza:99.8% - ≥95%Cor e Forma:White CrystalPeso molecular:307.43Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Fórmula:C26H45NO6SPureza:98.77% - 99.93%Cor e Forma:White SolidPeso molecular:499.7Diclofenac Potassium
CAS:Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.Fórmula:C14H10Cl2KNO2Pureza:99.93%Cor e Forma:White SolidPeso molecular:334.24CASP3 Activator 1541
CAS:CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.Fórmula:C24H17N3O4Pureza:98.84%Cor e Forma:SolidPeso molecular:411.41Ref: TM-T8652
1mg34,00€5mg71,00€1mL*10mM (DMSO)86,00€10mg105,00€25mg215,00€50mg344,00€100mg532,00€200mg740,00€5,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Fórmula:C18H16O5Pureza:97.53%Cor e Forma:SolidPeso molecular:312.32L67
CAS:L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).Fórmula:C16H14Br2N4O4Pureza:98.34% - 99.56%Cor e Forma:SolidPeso molecular:486.11AVN-944
CAS:AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.Fórmula:C25H27N5O5Pureza:99.07% - ≥95%Cor e Forma:White SolidPeso molecular:477.51Ref: TM-T1979
1mg56,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg130,00€25mg245,00€50mg358,00€100mg537,00€200mg763,00€Taurodeoxycholic acid sodium hydrate
CAS:Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.Fórmula:C26H46NNaO7SPureza:99.95%Cor e Forma:SolidPeso molecular:539.70Ospemifene
CAS:Ospemifene (FC-1271a) is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.Fórmula:C24H23ClO2Pureza:99.95%Cor e Forma:SolidPeso molecular:378.895,7-Dihydroxychromone
CAS:1.Fórmula:C9H6O4Pureza:99.76% - ≥95%Cor e Forma:Yellow SolidPeso molecular:178.14Ref: TM-T5S1805
1mg44,00€1mL*10mM (DMSO)75,00€5mg84,00€10mg119,00€25mg197,00€50mg294,00€100mg437,00€500mg954,00€Boc-Asp(OMe)-fluoromethyl ketone
CAS:Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.Fórmula:C11H18FNO5Pureza:≥98%Cor e Forma:SolidPeso molecular:263.26(E/Z)-Necrosulfonamide
CAS:(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.Fórmula:C18H15N5O6S2Pureza:97.62% - 98%Cor e Forma:SolidPeso molecular:461.47Lobaplatin
CAS:Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.Fórmula:C9H18N2O3PtPureza:98.00% - 99.96%Cor e Forma:White SolidPeso molecular:397.33Z-DEVD-FMK
CAS:Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,Fórmula:C30H41FN4O12Pureza:96.19% - 99.69%Cor e Forma:SolidPeso molecular:668.66Diethylnorspermine HBr
CAS:DENSPM is a potent polyamine analog that induces SSAT, arrests the cell cycle, and triggers apoptosis in various cancer cells.Fórmula:C13H36Br4N4Cor e Forma:SolidPeso molecular:568.075Arnicolide D
CAS:Arnicolide D is a sesquiterpene lactone.Fórmula:C19H24O5Pureza:96.66% - 99.93%Cor e Forma:White SolidPeso molecular:332.39EF24
CAS:EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.Fórmula:C19H15F2NOPureza:99.71%Cor e Forma:SolidPeso molecular:311.33Ref: TM-T27242
1mg38,00€5mg80,00€1mL*10mM (DMSO)88,00€10mg126,00€25mg222,00€50mg334,00€100mg505,00€500mg1.071,00€1g1.431,00€PAC-1
CAS:PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.Fórmula:C23H28N4O2Pureza:96.78% - 99.76%Cor e Forma:White SolidPeso molecular:392.49
