Ferroptose
A ferroptose é uma forma de morte celular regulada caracterizada pelo acúmulo de peróxidos lipídicos e estresse oxidativo dependente de ferro. Ao contrário da apoptose, a ferroptose não é impulsionada por caspases, mas pelo fracasso das defesas antioxidantes celulares, levando à morte celular. Inibidores e indutores de ferroptose são críticos para estudar essa via única de morte celular, que está implicada em várias doenças, incluindo câncer, neurodegeneração e lesão por isquemia-reperfusão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de ferroptose de alta qualidade para apoiar sua pesquisa em mecanismos de morte celular, estresse oxidativo e patologia de doenças.
Foram encontrados 226 produtos de "Ferroptose"
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Coenzyme Q10
CAS:Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.Fórmula:C59H90O4Pureza:99.14% - 99.88%Cor e Forma:DrypowderPeso molecular:863.34SP-420
CAS:SP-420 is a novel orally active iron chelator.Fórmula:C16H21NO6SPureza:99.39%Cor e Forma:SolidPeso molecular:355.41ML-210
CAS:ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Fórmula:C22H20Cl2N4O4Pureza:97% - 99.03%Cor e Forma:SolidPeso molecular:475.32Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Fórmula:C24H27NO5SPureza:98% - 99.8%Cor e Forma:Yellow SolidPeso molecular:441.54L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS:L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.Fórmula:C8H18N2O3SPureza:97.07% - ≥98%Cor e Forma:White Fine PowderPeso molecular:222.31DL-Buthionine-(S,R)-sulfoximine
CAS:DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.Fórmula:C8H18N2O3SPureza:98% - 99.64%Cor e Forma:White Fine PowderPeso molecular:222.31SRS16-86
CAS:SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.Fórmula:C26H32N4O2Pureza:97.73%Cor e Forma:SolidPeso molecular:432.56Pseudolaric Acid B
CAS:Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Fórmula:C23H28O8Pureza:98.91% - 99.84%Cor e Forma:SolidPeso molecular:432.46Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Fórmula:C13H15NO2SPureza:99.76% - 99.94%Cor e Forma:White SolidPeso molecular:249.33Levobupivacaine
CAS:Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.Fórmula:C18H28N2OPureza:99.72%Cor e Forma:SolidPeso molecular:288.43Liproxstatin-1
CAS:Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).Fórmula:C19H21ClN4Pureza:97.11% - 99.44%Cor e Forma:SolidPeso molecular:340.85Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Cor e Forma:SolidPeso molecular:393.89SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFórmula:C14H8N2OPureza:97.63% - 99.82%Cor e Forma:SolidPeso molecular:220.23NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Fórmula:C45H82N11O17P3Pureza:98.73% - 99.05%Cor e Forma:SolidPeso molecular:1142.12L-Cystine
CAS:<p>L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of</p>Fórmula:C6H12N2O4S2Pureza:99.59% - 99.85%Cor e Forma:White Solid PowderPeso molecular:240.30Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Fórmula:C18H19N3O3SPureza:98.61% - 99.87%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:357.43JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Fórmula:C20H20Cl2N4O4Pureza:98.02% - 98.4%Cor e Forma:SolidPeso molecular:451.3L-Glutamic acid
CAS:<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Fórmula:C5H9NO4Pureza:99.14% - 99.55%Cor e Forma:White Solid CrystallinePeso molecular:147.13ML385
CAS:ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.Fórmula:C29H25N3O4SPureza:98.08% - >99.99%Cor e Forma:SolidPeso molecular:511.59Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Fórmula:C13H13N3OSPureza:99.25% - >99.99%Cor e Forma:SolidPeso molecular:259.33
