Ferroptose
A ferroptose é uma forma de morte celular regulada caracterizada pelo acúmulo de peróxidos lipídicos e estresse oxidativo dependente de ferro. Ao contrário da apoptose, a ferroptose não é impulsionada por caspases, mas pelo fracasso das defesas antioxidantes celulares, levando à morte celular. Inibidores e indutores de ferroptose são críticos para estudar essa via única de morte celular, que está implicada em várias doenças, incluindo câncer, neurodegeneração e lesão por isquemia-reperfusão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de ferroptose de alta qualidade para apoiar sua pesquisa em mecanismos de morte celular, estresse oxidativo e patologia de doenças.
Foram encontrados 229 produtos para "Ferroptose".
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(-)-Epicatechin
CAS:(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localizationFórmula:C15H14O6Pureza:98.55% - 98.80%Cor e Forma:SolidPeso molecular:290.27UAMC-3203 hydrochloride
CAS:UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.Fórmula:C25H38ClN5O2SPureza:99.62%Cor e Forma:White SolidPeso molecular:508.12Baicalein monohydrate
CAS:Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.Fórmula:C15H12O6Cor e Forma:SolidPeso molecular:288.25Ferrostatin-1
CAS:Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!Fórmula:C15H22N2O2Pureza:96.1% - 99.68%Cor e Forma:Brown SolidPeso molecular:262.35CIL56
CAS:CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).Fórmula:C23H27N3O5S2Pureza:99.74% - 99.91%Cor e Forma:SolidPeso molecular:489.61Ref: TM-T4309
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)81,00€10mg109,00€25mg178,00€50mg284,00€100mg434,00€Hemin
CAS:Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Fórmula:C34H32ClFeN4O4Pureza:97.16% - 99.97%Cor e Forma:Black SolidPeso molecular:651.94DihydroarteMisinic acid
CAS:DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinalFórmula:C15H24O2Pureza:99.06% - 99.17%Cor e Forma:SolidPeso molecular:236.35Arteannuin B
CAS:1. Arteannuin B has potent antimalarial activity.Fórmula:C15H20O3Pureza:98% - 99.89%Cor e Forma:White SolidPeso molecular:248.32Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Fórmula:C10H17NO3Pureza:98.75% - 99.57%Cor e Forma:White SolidPeso molecular:199.25Ref: TM-T4414
5mg70,00€1mL*10mM (DMSO)77,00€10mg100,00€25mg195,00€50mg349,00€100mg618,00€500mg1.251,00€DL-α-Tocopherol
CAS:DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.Fórmula:C29H50O2Pureza:99.61% - 99.90%Cor e Forma:SolidPeso molecular:430.71SRS11-92
CAS:SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1Fórmula:C22H28N2O2Pureza:98.58%Cor e Forma:White SolidPeso molecular:352.47Ref: TM-T8922
10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1mg43,00€5mg75,00€1mL*10mM (DMSO)100,00€Deferitrin
CAS:Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.Fórmula:C11H11NO4SPureza:98.71%Cor e Forma:SolidPeso molecular:253.27Ref: TM-T19692
1mg99,00€1mL*10mM (DMSO)205,00€5mg222,00€10mg344,00€25mg550,00€50mg773,00€100mg1.063,00€1R,3S-RSL 3
CAS:1R,3S-RSL 3 is a harmala alkaloid.Fórmula:C23H21ClN2O5Pureza:99.51%Cor e Forma:SolidPeso molecular:440.88Ref: TM-T9561
1mg86,00€5mg177,00€1mL*10mM (DMSO)207,00€10mg265,00€25mg427,00€50mg605,00€100mg800,00€200mg1.071,00€Setanaxib
CAS:Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.Fórmula:C21H19ClN4O2Pureza:93.46% - 99.31%Cor e Forma:Yellow SolidPeso molecular:394.85Dp44mT
CAS:Dp44mT, a effective iron chelator, has selective antitumor activity.Fórmula:C14H15N5SPureza:99% - 99.02%Cor e Forma:SolidPeso molecular:285.37Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Fórmula:C18H22O4Pureza:97.82% - 99.91%Cor e Forma:Brown SolidPeso molecular:302.36NADPH tetrasodium salt
CAS:NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFórmula:C21H26N7Na4O17P3Pureza:97.15% - >99.99%Cor e Forma:Yellow SolidPeso molecular:833.35SP-420
CAS:SP-420 is a novel orally active iron chelator.Fórmula:C16H21NO6SPureza:99.39%Cor e Forma:White SolidPeso molecular:355.41Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Fórmula:C24H27NO5SPureza:98% - 99.8%Cor e Forma:SolidPeso molecular:441.54Ref: TM-T3170
2mg39,00€5mg58,00€1mL*10mM (DMSO)66,00€10mg94,00€25mg163,00€50mg289,00€100mg530,00€500mg1.108,00€SRS16-86
CAS:SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.Fórmula:C26H32N4O2Pureza:97.73%Cor e Forma:SolidPeso molecular:432.56Ref: TM-T9073
1mg34,00€2mg49,00€5mg73,00€1mL*10mM (DMSO)81,00€10mg108,00€25mg203,00€50mg306,00€100mg459,00€
