Ferroptose
A ferroptose é uma forma de morte celular regulada caracterizada pelo acúmulo de peróxidos lipídicos e estresse oxidativo dependente de ferro. Ao contrário da apoptose, a ferroptose não é impulsionada por caspases, mas pelo fracasso das defesas antioxidantes celulares, levando à morte celular. Inibidores e indutores de ferroptose são críticos para estudar essa via única de morte celular, que está implicada em várias doenças, incluindo câncer, neurodegeneração e lesão por isquemia-reperfusão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de ferroptose de alta qualidade para apoiar sua pesquisa em mecanismos de morte celular, estresse oxidativo e patologia de doenças.
Foram encontrados 229 produtos para "Ferroptose".
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Pseudolaric Acid B
CAS:Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Fórmula:C23H28O8Pureza:98.91% - 99.84%Cor e Forma:White SolidPeso molecular:432.46Levobupivacaine
CAS:Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.Fórmula:C18H28N2OPureza:99.72%Cor e Forma:SolidPeso molecular:288.43Ref: TM-T1787
5mg46,00€1mL*10mM (DMSO)47,00€10mg59,00€25mg87,00€50mg129,00€100mg178,00€200mg268,00€500mg460,00€Liproxstatin-1
CAS:Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).Fórmula:C19H21ClN4Pureza:97.11% - 99.44%Cor e Forma:Yellow SolidPeso molecular:340.85Ref: TM-T2376
1mg37,00€5mg80,00€1mL*10mM (DMSO)80,00€10mg123,00€25mg230,00€50mg369,00€100mg470,00€200mg675,00€Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.94%Cor e Forma:White SolidPeso molecular:393.89SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFórmula:C14H8N2OPureza:97.63% - 99.82%Cor e Forma:Yellow SolidPeso molecular:220.23L-Cystine
CAS:L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation ofFórmula:C6H12N2O4S2Pureza:99.59% - 99.95%Cor e Forma:White SolidPeso molecular:240.3Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Fórmula:C18H19N3O3SPureza:98.61% - 99.87%Cor e Forma:SolidPeso molecular:357.43L-Glutamic acid
CAS:L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!Fórmula:C5H9NO4Pureza:99.55% - 99.88%Cor e Forma:White SolidPeso molecular:147.13ML385
CAS:ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.Fórmula:C29H25N3O4SPureza:98.08% - >99.99%Cor e Forma:White SolidPeso molecular:511.59Ref: TM-T4360
5mg49,00€1mL*10mM (DMSO)56,00€10mg74,00€25mg144,00€50mg230,00€100mg356,00€200mg532,00€500mg852,00€Trigonelline
CAS:Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.Fórmula:C7H7NO2Pureza:97.58% - 99.49%Cor e Forma:White SolidPeso molecular:137.14PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Fórmula:C9H15NO3Pureza:99.22%Cor e Forma:SolidPeso molecular:185.22Ref: TM-T6954
5mg49,00€1mL*10mM (DMSO)54,00€10mg70,00€25mg133,00€50mg195,00€100mg349,00€200mg518,00€500mg830,00€Atorvastatin hemicalcium salt
CAS:Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.Fórmula:C33H34FN2O5CaPureza:99.66% - >99.99%Cor e Forma:White SolidPeso molecular:577.67Erastin
CAS:Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!Fórmula:C30H31ClN4O4Pureza:98% - 99.91%Cor e Forma:White SolidPeso molecular:547.04Ref: TM-T1765
1mg46,00€2x1mg59,00€5x1mg93,00€10x1mg120,00€25x1mg192,00€50x1mg284,00€100x1mg421,00€200x1mg618,00€FIN56
CAS:FIN56 is a specific inducer of ferroptosis.Fórmula:C25H31N3O5S2Pureza:99.72% - 99.78%Cor e Forma:SolidPeso molecular:517.66Ref: TM-T4066
2mg39,00€5mg59,00€1mL*10mM (DMSO)69,00€10mg94,00€25mg182,00€50mg324,00€100mg507,00€200mg710,00€Chrysosplenetin
CAS:Chrysosplenetin is a metabolic inhibitor of artemisinin.Fórmula:C19H18O8Pureza:97.43% - 98.4%Cor e Forma:Yellow SolidPeso molecular:374.34Ref: TM-TJS1159
1mg57,00€5mg120,00€1mL*10mM (DMSO)133,00€10mg178,00€25mg329,00€50mg485,00€100mg692,00€500mg1.404,00€Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Fórmula:C16H18N2OS·HBrPureza:97.71% - >99.99%Cor e Forma:SolidPeso molecular:367.3Pifithrin-β hydrobromide
CAS:Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.Fórmula:C16H17BrN2SPureza:99.24% - 99.74%Cor e Forma:White SolidPeso molecular:349.29Levobupivacaine hydrochloride
CAS:Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.Fórmula:C18H28N2O·HClPureza:99.74%Cor e Forma:SolidPeso molecular:324.89Ammonium iron(III) citrate
CAS:Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.Fórmula:C12H22FeN3O14Pureza:98%Cor e Forma:Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of AmmoniaPeso molecular:488.16U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Fórmula:C29H40N2O3Pureza:97.50% - 98.66%Cor e Forma:White SolidPeso molecular:464.64
