Ferroptose

A ferroptose é uma forma de morte celular regulada caracterizada pelo acúmulo de peróxidos lipídicos e estresse oxidativo dependente de ferro. Ao contrário da apoptose, a ferroptose não é impulsionada por caspases, mas pelo fracasso das defesas antioxidantes celulares, levando à morte celular. Inibidores e indutores de ferroptose são críticos para estudar essa via única de morte celular, que está implicada em várias doenças, incluindo câncer, neurodegeneração e lesão por isquemia-reperfusão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de ferroptose de alta qualidade para apoiar sua pesquisa em mecanismos de morte celular, estresse oxidativo e patologia de doenças.

Foram encontrados 225 produtos de "Ferroptose"

Pureza (%)

100

produtos por página.

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(-)-Epicatechin
CAS:
- 490-46-0
(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization
Fórmula:C₁₅H₁₄O₆
Pureza:98.55% - 98.80%
Cor e Forma:Solid
Peso molecular:290.27
Ref: TM-T2856
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CIL56
CAS:
- 300802-28-2
CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).
Fórmula:C₂₃H₂₇N₃O₅S₂
Pureza:99.46% - 99.91%
Cor e Forma:Solid
Peso molecular:489.61
Ref: TM-T4309
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Hemin
CAS:
- 16009-13-5
Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.
Fórmula:C₃₄H₃₂ClFeN₄O₄
Pureza:97.169% - 99.59%
Cor e Forma:Dark Purple Crystalline Powder
Peso molecular:651.94
Ref: TM-T5515
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DihydroarteMisinic acid
CAS:
- 85031-59-0
DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal
Fórmula:C₁₅H₂₄O₂
Pureza:99.06% - 99.17%
Cor e Forma:Solid
Peso molecular:236.35
Ref: TM-THS1455
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Arteannuin B
CAS:
- 50906-56-4
1. Arteannuin B has potent antimalarial activity.
Fórmula:C₁₅H₂₀O₃
Pureza:98% - 99.8%
Cor e Forma:Solid
Peso molecular:248.32
Ref: TM-T3S1447
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UAMC-3203
CAS:
- 2271358-64-4
UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).
Fórmula:C₂₅H₃₇N₅O₂S
Pureza:97.052% - 99.72%
Cor e Forma:Solid
Peso molecular:471.66
Ref: TM-T5343
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Eprenetapopt
CAS:
- 5291-32-7
Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.
Fórmula:C₁₀H₁₇NO₃
Pureza:98.75% - 99.57%
Cor e Forma:Solid
Peso molecular:199.25
Ref: TM-T4414
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D-glutamine
CAS:
- 5959-95-5
D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
Fórmula:C₅H₁₀N₂O₃
Pureza:99.99%
Cor e Forma:White Or Off-White Powder
Peso molecular:146.14
Ref: TM-T6468
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RSL3
CAS:
- 1219810-16-8
View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.
Fórmula:C₂₃H₂₁ClN₂O₅
Pureza:98% - 99.96%
Cor e Forma:Solid
Peso molecular:440.88
Ref: TM-T3646
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Piperlongumine
CAS:
- 20069-09-4
Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.
Fórmula:C₁₇H₁₉NO₅
Pureza:97.03% - 99.90%
Cor e Forma:Solid
Peso molecular:317.34
Ref: TM-T6947
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DL-α-Tocopherol
CAS:
- 10191-41-0
DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.
Fórmula:C₂₉H₅₀O₂
Pureza:99.61% - 99.90%
Cor e Forma:Light Yellow Liquid Viscous
Peso molecular:430.71
Ref: TM-TMA2394
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(E)-Ferulic acid
CAS:
- 537-98-4
(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of
Fórmula:C₁₀H₁₀O₄
Pureza:99.63%
Cor e Forma:Solid
Peso molecular:194.18
Ref: TM-T5679
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SRS11-92
CAS:
- 1467047-25-1
SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1
Fórmula:C₂₂H₂₈N₂O₂
Pureza:98.58%
Cor e Forma:Solid
Peso molecular:352.47
Ref: TM-T8922
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Deferitrin
CAS:
- 239101-33-8
Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.
Fórmula:C₁₁H₁₁NO₄S
Pureza:98.71%
Cor e Forma:Solid
Peso molecular:253.27
Ref: TM-T19692
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ML162
CAS:
- 1035072-16-2
ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.
Fórmula:C₂₃H₂₂Cl₂N₂O₃S
Pureza:98.42% - 99.55%
Cor e Forma:Solid
Peso molecular:477.4
Ref: TM-T8970
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1R,3S-RSL 3
CAS:
- 1219810-13-5
1R,3S-RSL 3 is a harmala alkaloid.
Fórmula:C₂₃H₂₁ClN₂O₅
Pureza:99.51%
Cor e Forma:Solid
Peso molecular:440.88
Ref: TM-T9561
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PD146176
CAS:
- 4079-26-9
PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.
Fórmula:C₁₅H₁₁NS
Pureza:98.00%
Cor e Forma:Solid
Peso molecular:237.32
Ref: TM-T7530
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Piperazine Erastin
CAS:
- 1538593-71-3
Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.
Fórmula:C₃₅H₄₁ClN₆O₄
Pureza:99.52%
Cor e Forma:Solid
Peso molecular:645.19
Ref: TM-T16540
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Setanaxib
CAS:
- 1218942-37-0
Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
Fórmula:C₂₁H₁₉ClN₄O₂
Pureza:93.468% - 99.31%
Cor e Forma:Solid
Peso molecular:394.85
Ref: TM-T6099
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Dp44mT
CAS:
- 152095-12-0
Dp44mT, a effective iron chelator, has selective antitumor activity.
Fórmula:C₁₄H₁₅N₅S
Pureza:99% - 99.02%
Cor e Forma:Solid
Peso molecular:285.37
Ref: TM-T6821