
Microtúbulo associado
Os inibidores de proteínas associadas aos microtúbulos têm como alvo as proteínas que interagem com os microtúbulos, os componentes estruturais do citoesqueleto da célula que são essenciais para a divisão celular. Essas proteínas regulam a estabilidade e a dinâmica dos microtúbulos durante a mitose. A inibição de proteínas associadas aos microtúbulos pode interromper a função dos microtúbulos, levando à parada do ciclo celular e à apoptose, especialmente em células cancerígenas de rápida divisão. Esses inibidores são amplamente utilizados na pesquisa do câncer e no desenvolvimento de medicamentos. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteínas associadas aos microtúbulos de alta qualidade para apoiar sua pesquisa em divisão celular, dinâmica do citoesqueleto e terapia do câncer.
Foram encontrados 261 produtos de "Microtúbulo associado"
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Tubulin polymerization-IN-7
CAS:<p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>Fórmula:C28H24N4O6SCor e Forma:SolidPeso molecular:544.58Anticancer agent 60
CAS:<p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>Fórmula:C27H33N5O4SCor e Forma:SolidPeso molecular:523.65SB26019
CAS:<p>SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.</p>Fórmula:C24H20O4Cor e Forma:SolidPeso molecular:372.41AMXI-5001
CAS:<p>AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.</p>Fórmula:C25H20FN5O3Cor e Forma:SolidPeso molecular:457.46Tubulin inhibitor 20
CAS:<p>Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].</p>Fórmula:C19H18O4Cor e Forma:SolidPeso molecular:310.34Tubulin inhibitor 26
CAS:<p>Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.</p>Fórmula:C17H19N3O3Cor e Forma:SolidPeso molecular:313.35Microtubule inhibitor 5
CAS:<p>Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.</p>Fórmula:C22H15FN2O4Cor e Forma:SolidPeso molecular:390.36Tubulin polymerization-IN-37
CAS:<p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>Fórmula:C19H20N2O4Cor e Forma:SolidPeso molecular:340.37THK-5117
CAS:<p>THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.</p>Fórmula:C19H19FN2O2Cor e Forma:SolidPeso molecular:326.36OXi8007
CAS:<p>OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.</p>Fórmula:C26H24NNa2O10PCor e Forma:SolidPeso molecular:587.428Hydromethylthionine HBr
CAS:<p>Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.</p>Fórmula:C16H21Br2N3SCor e Forma:SolidPeso molecular:447.233(R)-TTBK1-IN-1
CAS:<p>(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s & tauopathies.</p>Fórmula:C18H19N5O2Cor e Forma:SolidPeso molecular:337.38Tubulin polymerization-IN-25
CAS:<p>Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.</p>Fórmula:C24H18N2O3SCor e Forma:SolidPeso molecular:414.48Tubulin polymerization-IN-15
CAS:<p>Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].</p>Fórmula:C18H17N3O4Cor e Forma:SolidPeso molecular:339.35Tubulin polymerization-IN-20
CAS:<p>Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.</p>Fórmula:C25H24FNO5Cor e Forma:SolidPeso molecular:437.46Tubulin inhibitor 18
CAS:<p>"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."</p>Fórmula:C22H26O5Cor e Forma:SolidPeso molecular:370.44Tubulin/MMP-IN-1
<p>Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.</p>Fórmula:C38H44NO9PCor e Forma:SolidPeso molecular:689.73Tubulin inhibitor 12
CAS:<p>New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.</p>Fórmula:C24H20N2OCor e Forma:SolidPeso molecular:352.43Tau tracer 1
CAS:<p>Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.</p>Fórmula:C34H23N5O2Cor e Forma:SolidPeso molecular:533.591Iso-Fludelone
CAS:<p>Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.</p>Fórmula:C27H36F3NO6Cor e Forma:SolidPeso molecular:527.57
