Microtúbulo associado
Os inibidores de proteínas associadas aos microtúbulos têm como alvo as proteínas que interagem com os microtúbulos, os componentes estruturais do citoesqueleto da célula que são essenciais para a divisão celular. Essas proteínas regulam a estabilidade e a dinâmica dos microtúbulos durante a mitose. A inibição de proteínas associadas aos microtúbulos pode interromper a função dos microtúbulos, levando à parada do ciclo celular e à apoptose, especialmente em células cancerígenas de rápida divisão. Esses inibidores são amplamente utilizados na pesquisa do câncer e no desenvolvimento de medicamentos. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteínas associadas aos microtúbulos de alta qualidade para apoiar sua pesquisa em divisão celular, dinâmica do citoesqueleto e terapia do câncer.
Foram encontrados 261 produtos de "Microtúbulo associado"
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Antitumor agent-68
CAS:<p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>Fórmula:C17H11NO2Cor e Forma:SolidPeso molecular:261.27Antitumor agent-71
CAS:<p>Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.</p>Fórmula:C26H31N5O4SCor e Forma:SolidPeso molecular:509.62IDT
CAS:<p>IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.</p>Fórmula:C8H5NS2Pureza:98%Cor e Forma:SolidPeso molecular:179.26DHNQ
CAS:<p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>Fórmula:C18H14N2OCor e Forma:SolidPeso molecular:274.32D011-2120
CAS:<p>D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.</p>Fórmula:C17H15NO3Pureza:98%Cor e Forma:SolidPeso molecular:281.31DAT1
CAS:<p>DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.</p>Fórmula:C17H15N3O2SPureza:98%Cor e Forma:SolidPeso molecular:325.38Acodazole
CAS:<p>Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.</p>Fórmula:C20H19N5OPureza:98%Cor e Forma:SolidPeso molecular:345.4Acodazole hydrochloride
CAS:Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.Fórmula:C20H20ClN5OPureza:98%Cor e Forma:SolidPeso molecular:381.86LDN-193665
CAS:LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Fórmula:C15H11FN4OSPureza:98%Cor e Forma:SolidPeso molecular:314.34GF 15
CAS:<p>GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.</p>Fórmula:C23H21ClO6Pureza:98%Cor e Forma:SolidPeso molecular:428.86TOK-8801
CAS:<p>TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.</p>Fórmula:C17H21N3OSPureza:99.97%Cor e Forma:SolidPeso molecular:315.43Mivobulin
CAS:<p>Mivobulin is an inhibitor of tubulin .</p>Fórmula:C17H19N5O2Pureza:98%Cor e Forma:SolidPeso molecular:325.37S-methyl DM1
CAS:<p>S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.</p>Fórmula:C36H50ClN3O10SPureza:98%Cor e Forma:SolidPeso molecular:752.31Cevipabulin
CAS:<p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>Fórmula:C18H18ClF5N6OPureza:99.53%Cor e Forma:SolidPeso molecular:464.82Tau-aggregation and neuroinflammation-IN-1
CAS:<p>Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.</p>Fórmula:C25H20N2O7Pureza:99.85%Cor e Forma:SolidPeso molecular:460.44CCB02
CAS:CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Fórmula:C14H9N3OPureza:98.38%Cor e Forma:SolidPeso molecular:235.24S516
CAS:S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.Fórmula:C21H19N5O4SPureza:98%Cor e Forma:SolidPeso molecular:437.47Tubulin inhibitor 8
CAS:<p>Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.</p>Fórmula:C21H14N2O3Pureza:98.51% - 99.87%Cor e Forma:SolidPeso molecular:342.35LY3372689
CAS:<p>LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.</p>Fórmula:C16H22FN5O3SPureza:99.43% - 99.53%Cor e Forma:SolidPeso molecular:383.44DM1-SMe
CAS:<p>DM1-SMe (DM1-SSMe) potently inhibits microtubules, 3-10x stronger than Maytansine with IC50s of 0.003-0.01 nM in human cancer cells.</p>Fórmula:C36H50ClN3O10S2Pureza:99.61%Cor e Forma:SolidPeso molecular:784.38
