Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2615 produtos de "Cromatina/Epigenética"
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CD532
CAS:CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.Fórmula:C26H25F3N8OPureza:99.99%Cor e Forma:SolidPeso molecular:522.52OUL232
CAS:OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.Fórmula:C10H10N4O2SPureza:99.04%Cor e Forma:SolidPeso molecular:250.28AGI-43192
CAS:AGI-43192: potent MAT2A inhibitor, crosses blood-brain barrier, may help study SAM in CNS and treat cancer.Fórmula:C23H16ClF3N6OPureza:99.89%Cor e Forma:SolidPeso molecular:484.86Ref: TM-T9729
1mg72,00€5mg161,00€1mL*10mM (DMSO)172,00€10mg250,00€25mg411,00€50mg577,00€100mg772,00€500mg1.558,00€Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Fórmula:C27H21N3O3Pureza:99.22%Cor e Forma:SolidPeso molecular:435.47Ref: TM-T35570
1mg66,00€5mg144,00€1mL*10mM (DMSO)157,00€10mg245,00€25mg492,00€50mg710,00€100mg973,00€EZH2-IN-13
CAS:EZH2-IN-13 is a potent EZH2 inhibitor with potential anticancer activity.EZH2-IN-13 may be used to study diseases associated with EZH2 activity.Fórmula:C34H45N5O3Pureza:98.3%Cor e Forma:SolidPeso molecular:571.75DW14800
CAS:DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.Fórmula:C31H36N4O3Pureza:99.55% - 99.68%Cor e Forma:SolidPeso molecular:512.64Ref: TM-T11131
1mg93,00€2mg123,00€5mg205,00€1mL*10mM (DMSO)233,00€10mg358,00€25mg680,00€50mg898,00€100mg1.341,00€Flosequinan
CAS:Flosequinan is an arteriovenous vasodilator, which can effectively treat acute heart failure.Fórmula:C11H10FNO2SPureza:99.95%Cor e Forma:SolidPeso molecular:239.27Ref: TM-T31805
1mg175,00€1mL*10mM (DMSO)351,00€5mg394,00€10mg582,00€25mg888,00€50mg1.243,00€100mg1.674,00€500mg3.348,00€MAT2A-IN-9
CAS:MAT2A-IN-9, a 2-oxoquinazoline, inhibits MAT2A with antitumor effects on lymphomas and solid cancers.Fórmula:C14H8ClF3N4OPureza:99.17%Cor e Forma:SolidPeso molecular:340.69LEM-14
CAS:LEM-14 is a potent NSD2-specific inhibitor (IC50:132 μM).LEM-14 may be used in the study of multiple myeloma.
Fórmula:C25H26N4O4SPureza:98.3%Cor e Forma:SolidPeso molecular:478.56YLF-466D
CAS:YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.Fórmula:C29H20ClNO3Pureza:97.74%Cor e Forma:SolidPeso molecular:465.93Ref: TM-T13368
1mg34,00€5mg79,00€1mL*10mM (DMSO)82,00€10mg111,00€25mg188,00€50mg269,00€100mg371,00€200mg512,00€STS-E412
CAS:STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.Fórmula:C15H15ClN4O2Pureza:99.01%Cor e Forma:SolidPeso molecular:318.76HDAC6 degrader 9c
CAS:HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be used to study cancer or other diseases.Fórmula:C37H45N9O10Pureza:>99.99%Cor e Forma:SolidPeso molecular:775.81LSD1-IN-20
CAS:LSD1-IN-20: Dual LSD1/G9a inhibitor, Ki 0.44/0.68 μM; hampers THP-1, MDA-MB-231 cell growth with IC50 0.51/1.60 μM at 72h.Fórmula:C27H38N6O2Pureza:97.17% - 99.57%Cor e Forma:SolidPeso molecular:478.63SK-575
CAS:SK-575 is a potent PARP1-degrading agent effective against BRCA1/2 mutant cancers, even at low doses, and enhances tumor inhibition in mice.Fórmula:C47H53FN8O8Pureza:99.39%Cor e Forma:SolidPeso molecular:876.97JAK-STAT-IN-1
CAS:JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.Fórmula:C21H21N5O2Pureza:99.59%Cor e Forma:SolidPeso molecular:375.42DC-BPi-03
CAS:DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC 50 of 698.3 nM and a K d of 2.81 μM .Fórmula:C14H14N4O2SPureza:98.96%Cor e Forma:SolidPeso molecular:302.35ACY-1083
CAS:ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy.Fórmula:C17H18F2N4O2Pureza:99.19% - 99.43%Cor e Forma:SolidPeso molecular:348.35Ref: TM-T10244
1mg144,00€5mg295,00€1mL*10mM (DMSO)326,00€10mg504,00€25mg795,00€50mg1.108,00€100mg1.494,00€500mg2.997,00€CMP-5
CAS:CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection.Fórmula:C21H21N3Pureza:98.68%Cor e Forma:SolidPeso molecular:315.41Ref: TM-T10850
1mg44,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg137,00€25mg225,00€50mg334,00€100mg494,00€500mg1.054,00€BRD4 Inhibitor-20
CAS:BRD4 Inhibitor-20 is a potent bromodomain protein 4 (BRD4) inhibitor with oral activity.
Fórmula:C18H18N2O4SPureza:99.84%Cor e Forma:SolidPeso molecular:358.41KRH102140
CAS:KRH102140 is a PHD2 activator that reduces angiogenesis by inhibiting HIF-1alpha, used in cardiovascular disease research.Fórmula:C25H24FNOPureza:98.31% - 99.61%Cor e Forma:SolidPeso molecular:373.46
