Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2615 produtos de "Cromatina/Epigenética"
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MS0124
CAS:MS0124 is a potent and selective G9A-like protein (GLP) inhibitor with IC50 values of 13±4 nM and 440±63 nM, respectively.
Fórmula:C20H29N5O3Pureza:98.97%Cor e Forma:SolidPeso molecular:387.48CARM1-IN-1
CAS:CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.Fórmula:C26H21Br2NO3Pureza:98.24%Cor e Forma:SolidPeso molecular:555.26Ref: TM-T10682L
1mg34,00€5mg84,00€1mL*10mM (DMSO)92,00€10mg120,00€25mg236,00€50mg385,00€100mg600,00€200mg837,00€Cedazuridine
CAS:Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.Fórmula:C9H14F2N2O5Pureza:99.66%Cor e Forma:SolidPeso molecular:268.21Butyzamide
CAS:Butyzamide: oral Mpl activator, non-peptide, antagonizes TPO receptors, boosts hMpl, Ba/F3 cells, and enhances platelets in mice.Fórmula:C29H32Cl2N2O5SPureza:99.39% - 99.83%Cor e Forma:SoildPeso molecular:591.55Ref: TM-T67894
1mg149,00€5mg253,00€1mL*10mM (DMSO)329,00€10mg371,00€25mg573,00€50mg862,00€100mg1.305,00€200mg1.755,00€OXFBD04
CAS:OXFBD04: Potent BRD4 inhibitor, IC50=166nM, acts on BET bromodomains; moderate CREBBP affinity; anti-cancer properties.Fórmula:C17H16N2O3Pureza:99.56%Cor e Forma:SolidPeso molecular:296.32Ref: TM-T12338
1mg50,00€2mg73,00€5mg109,00€1mL*10mM (DMSO)119,00€10mg172,00€25mg321,00€50mg477,00€100mg648,00€200mg893,00€HDAC8-IN-20a
CAS:HDAC8-IN-20a (HDAC8 inhibitor-20a) is a potent and selective HDAC8 inhibitor with an IC50 of 27 nM.Fórmula:C15H15NO4Pureza:98.24% - 99.22%Cor e Forma:SolidPeso molecular:273.28Ref: TM-T24133
1mg173,00€1mL*10mM (DMSO)380,00€5mg424,00€10mg585,00€25mg873,00€50mg1.134,00€100mg1.468,00€200mg1.963,00€Izencitinib
CAS:Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.Fórmula:C22H26N8Pureza:99.82%Cor e Forma:SolidPeso molecular:402.50Ref: TM-T35898
1mg84,00€5mg177,00€1mL*10mM (DMSO)195,00€10mg281,00€25mg567,00€50mg888,00€100mg1.431,00€200mg1.963,00€NSC668394
CAS:NSC668394 is an ezrin phosphorylation inhibitor.NSC668394 has antitumor activity and increases ezrin cleavage.NSC668394 can be used to study tumor metastasis.Fórmula:C17H12Br2N2O3Pureza:99.29% - 99.29%Cor e Forma:SolidPeso molecular:452.1GRK6-IN-1
CAS:GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.Fórmula:C22H23ClN6O2Pureza:99.37%Cor e Forma:SolidPeso molecular:438.91Ref: TM-T62518
1mg54,00€5mg114,00€1mL*10mM (DMSO)126,00€10mg178,00€25mg409,00€50mg708,00€100mg1.153,00€ZEN-3411
CAS:ZEN-3411 is an BET inhibitor that inhibits BRD4(BD1), BRD4(BD2), and BRD4(BD1BD2) and suppresses the growth of tumor cells overproducing BET proteins.Fórmula:C21H20N4O2Pureza:97.51% - 98.84%Cor e Forma:SolidPeso molecular:360.41TM2-115
CAS:TM2-115 is a inhibitor of malaria parasite histone methyltransferases that results in rapid and irreversible parasite death [1].Fórmula:C28H38N6O2Pureza:97.67%Cor e Forma:SolidPeso molecular:490.64TNG908
CAS:TNG908, a brain-penetrant PRMT5 inhibitor, is 15x more selective for MTAP mutant vs WT lines, useful in cancer studies.Fórmula:C21H23N5O2SPureza:98.08% - 98.24%Cor e Forma:SolidPeso molecular:409.51Ref: TM-T73494
1mg66,00€5mg145,00€1mL*10mM (DMSO)158,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€TGP-377/421
CAS:TGP-377/421 (Targapre-miR-377/421) is a potent miR-377 and miR-421 dual inhibitor that inhibits miR-377 and miR-421 by binding to their functional sites.Fórmula:C20H16N6Pureza:97.02%Cor e Forma:SolidPeso molecular:340.38Ref: TM-T61085
1mg63,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg430,00€50mg695,00€100mg973,00€500mg1.945,00€AGI-24512
CAS:AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells inFórmula:C24H24N4O2Pureza:98.55%Cor e Forma:SolidPeso molecular:400.47Ref: TM-T14141
1mg66,00€5mg145,00€1mL*10mM (DMSO)195,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€200mg982,00€Corin
CAS:Corin is an irreversible inhibitor of HDAC1(IC50 = 147 nM) and LSD1(Ki = 110 nM).Fórmula:C26H28N4O2Pureza:99.6%Cor e Forma:SolidPeso molecular:428.53Ref: TM-T10864
1mg167,00€5mg409,00€1mL*10mM (DMSO)442,00€10mg605,00€25mg954,00€50mg1.288,00€100mg1.728,00€BAY-299
CAS:BAY-299 inhibits BRPF2, TAF1, and TAF1L with IC50s of 67, 8, and 106 nM.Fórmula:C25H23N3O4Pureza:99.53%Cor e Forma:SolidPeso molecular:429.47SIRT6-IN-5
CAS:SIRT6-IN-5: potent, selective SIRT6 inhibitor; IC50=34 μM; immunosuppressive, enhances chemo, boosts H3K9 acetylation, glucose uptake, curbs T-cell growth.Fórmula:C19H14N2O6Pureza:98.77%Cor e Forma:SolidPeso molecular:366.32PARP10-IN-2
CAS:PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and
Fórmula:C14H10N2O2Pureza:99.27%Cor e Forma:SolidPeso molecular:238.24Procainamide
CAS:Procainamide: DNMT1 inhibitor, Class 1A antiarrhythmic, promising for cancer and arrhythmia research.Fórmula:C13H21N3OPureza:99.79% - 99.92%Cor e Forma:SolidPeso molecular:235.33EB-47
CAS:EB-47 imitates NAD+, spans nicotinamide to adenosine sites, inhibits PARP-1 (IC50: 45 nM) and is less effective on ARTD5 (IC50: 410 nM).Fórmula:C24H27N9O6Pureza:99.81%Cor e Forma:SolidPeso molecular:537.53
