CymitQuimica logo
Cromatina/Epigenética

Cromatina/Epigenética

Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.

Subcategorias de "Cromatina/Epigenética"

Foram encontrados 2426 produtos de "Cromatina/Epigenética"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • Gandotinib
    Targetmol
    + Info

    Gandotinib

    CAS:
    LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).
    Fórmula:C23H25ClFN7O
    Pureza:99.33% - 99.86%
    Cor e Forma:Solid
    Peso molecular:469.94

    Ref: TM-T2638

  • CPI-637
    Targetmol
    + Info

    CPI-637

    CAS:
    <p>CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.</p>
    Fórmula:C22H22N6O
    Pureza:99.89% - 99.95%
    Cor e Forma:Solid
    Peso molecular:386.45

    Ref: TM-T6811

  • Cerdulatinib
    Targetmol
    + Info

    Cerdulatinib

    CAS:
    Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.
    Fórmula:C20H27N7O3S
    Pureza:98.74% - 99.49%
    Cor e Forma:Solid
    Peso molecular:445.54

    Ref: TM-T2487

  • PFI-1
    Targetmol
    + Info

    PFI-1

    CAS:
    PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.
    Fórmula:C16H17N3O4S
    Pureza:98.74% - 99.19%
    Cor e Forma:Solid
    Peso molecular:347.39

    Ref: TM-T6222

  • Acetyl Pentapeptide-1 acetate
    Targetmol
    + Info

    Acetyl Pentapeptide-1 acetate

    Acetyl Pentapeptide-1 acetate is an histone deacetylase inhibitor.
    Fórmula:C34H55N9O12
    Pureza:99.09%
    Cor e Forma:Solid
    Peso molecular:781.86

    Ref: TM-T38318L

  • Niraparib tosylate
    Targetmol
    + Info

    Niraparib tosylate

    CAS:
    <p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>
    Fórmula:C19H20N4O·C7H8O3S
    Pureza:99.34% - 99.87%
    Cor e Forma:Solid
    Peso molecular:492.59

    Ref: TM-T6892

  • WHI-P154
    Targetmol
    + Info

    WHI-P154

    CAS:
    WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.
    Fórmula:C16H14BrN3O3
    Pureza:98% - 99.67%
    Cor e Forma:Solid
    Peso molecular:376.2

    Ref: TM-T1985

  • 2-hexyl-4-Pentynoic Acid
    Targetmol
    + Info

    2-hexyl-4-Pentynoic Acid

    CAS:
    2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.
    Fórmula:C11H18O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:182.26

    Ref: TM-T21551

  • Mivebresib
    Targetmol
    + Info

    Mivebresib

    CAS:
    Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.
    Fórmula:C22H19F2N3O4S
    Pureza:98.74% - 99.32%
    Cor e Forma:Solid
    Peso molecular:459.47

    Ref: TM-T3712

  • Aurora kinase inhibitor-2
    Targetmol
    + Info

    Aurora kinase inhibitor-2

    CAS:
    Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).
    Fórmula:C23H20N4O3
    Pureza:98.66%
    Cor e Forma:Solid
    Peso molecular:400.43

    Ref: TM-T9040

  • MRTX9768
    Targetmol
    + Info

    MRTX9768

    CAS:
    MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.
    Fórmula:C24H17FN6O
    Pureza:97.02%
    Cor e Forma:Solid
    Peso molecular:424.43

    Ref: TM-T9575

  • 7BIO
    Targetmol
    + Info

    7BIO

    CAS:
    <p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>
    Fórmula:C16H10BrN3O2
    Pureza:99.67%
    Cor e Forma:Solid
    Peso molecular:356.17

    Ref: TM-T22012

  • MK-4827 Racemate
    Targetmol
    + Info

    MK-4827 Racemate

    CAS:
    MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for
    Fórmula:C19H20N4O
    Pureza:99.86%
    Cor e Forma:Solid
    Peso molecular:320.39

    Ref: TM-T22988

  • BEBT-908
    Targetmol
    + Info

    BEBT-908

    CAS:
    BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits HDAC (0.1 μM≤IC50≤1 μM).
    Fórmula:C23H25N9O3S
    Pureza:99.67%
    Cor e Forma:Solid
    Peso molecular:507.57

    Ref: TM-T16529

  • SGI-1776
    Targetmol
    + Info

    SGI-1776

    CAS:
    SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.
    Fórmula:C20H22F3N5O
    Pureza:99.3% - >99.99%
    Cor e Forma:Solid
    Peso molecular:405.42

    Ref: TM-T3078

  • NMS-P118
    Targetmol
    + Info

    NMS-P118

    CAS:
    <p>NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.</p>
    Fórmula:C20H24F3N3O2
    Pureza:98.79%
    Cor e Forma:Solid
    Peso molecular:395.42

    Ref: TM-T4472

  • AS8351
    Targetmol
    + Info

    AS8351

    CAS:
    AS8351 inhibits histone demethylase, used with various compounds to turn human lung fibroblasts into cardiomyocytes.
    Fórmula:C17H13N3O2
    Pureza:99.54% - 99.72%
    Cor e Forma:Solid
    Peso molecular:291.3

    Ref: TM-T4100

  • Delgocitinib EtOH
    Targetmol
    + Info

    Delgocitinib EtOH

    CAS:
    Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.
    Fórmula:C18H24N6O2
    Cor e Forma:Solid
    Peso molecular:356.43

    Ref: TM-T69950

  • O-304
    Targetmol
    + Info

    O-304

    CAS:
    O-304 is a pan-activator of AMP-activated protein kinase (AMPK).
    Fórmula:C16H11Cl2N3O2S
    Pureza:99.84% - ≥98%
    Cor e Forma:Solid
    Peso molecular:380.25

    Ref: TM-T7362

  • PF-06409577
    Targetmol
    + Info

    PF-06409577

    CAS:
    PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).
    Fórmula:C19H16ClNO3
    Pureza:95.17% - 98.21%
    Cor e Forma:Solid
    Peso molecular:341.79

    Ref: TM-T4427