Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2426 produtos de "Cromatina/Epigenética"
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Fedratinib
CAS:Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Fórmula:C27H36N6O3SPureza:97.31% - 99.96%Cor e Forma:SolidPeso molecular:524.68BI 2536
CAS:BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.Fórmula:C28H39N7O3Pureza:98% - 99.88%Cor e Forma:SolidPeso molecular:521.65Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Fórmula:C23H25ClFN7OPureza:99.33% - 99.86%Cor e Forma:SolidPeso molecular:469.94Bobcat339
CAS:<p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>Fórmula:C16H12ClN3OPureza:97.79% - 99.24%Cor e Forma:SolidPeso molecular:297.74Fluzoparib
CAS:Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.Fórmula:C22H16F4N6O2Pureza:98.53% - 99.63%Cor e Forma:SolidPeso molecular:472.4PFI-1
CAS:PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Fórmula:C16H17N3O4SPureza:98.74% - 99.19%Cor e Forma:SolidPeso molecular:347.39Acetyl Pentapeptide-1 acetate
Acetyl Pentapeptide-1 acetate is an histone deacetylase inhibitor.Fórmula:C34H55N9O12Pureza:99.09%Cor e Forma:SolidPeso molecular:781.86AZ9482
CAS:AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.Fórmula:C26H22N6O2Pureza:99.18% - 99.86%Cor e Forma:SolidPeso molecular:450.49Nicotinamide riboside chloride
CAS:NR, also SRT647, is a B3 vitamin form; precursor to NAD+.Fórmula:C11H15ClN2O5Pureza:98.92% - 99.86%Cor e Forma:SolidPeso molecular:290.74-Phenylbutyric acid
CAS:4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.Fórmula:C10H12O2Pureza:98.40% - 99.76%Cor e Forma:SolidPeso molecular:164.2Niraparib tosylate
CAS:<p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>Fórmula:C19H20N4O·C7H8O3SPureza:99.34% - 99.87%Cor e Forma:SolidPeso molecular:492.59WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Fórmula:C16H14BrN3O3Pureza:98% - 99.67%Cor e Forma:SolidPeso molecular:376.22-hexyl-4-Pentynoic Acid
CAS:2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.Fórmula:C11H18O2Pureza:98%Cor e Forma:SolidPeso molecular:182.26GSK199
CAS:GSK199 is a selective PAD4 inhibitor(IC50 of 200 nM in the absence of calcium).Fórmula:C24H29ClN6O2Pureza:99.44%Cor e Forma:SolidPeso molecular:468.98GSK343
CAS:GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity againstFórmula:C31H39N7O2Pureza:98% - 99.9%Cor e Forma:SolidPeso molecular:541.69Aurora kinase inhibitor-2
CAS:Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).Fórmula:C23H20N4O3Pureza:98.66%Cor e Forma:SolidPeso molecular:400.43MRTX9768
CAS:MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.Fórmula:C24H17FN6OPureza:97.02%Cor e Forma:SolidPeso molecular:424.437BIO
CAS:<p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>Fórmula:C16H10BrN3O2Pureza:99.67%Cor e Forma:SolidPeso molecular:356.17MK-4827 Racemate
CAS:MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity forFórmula:C19H20N4OPureza:99.86%Cor e Forma:SolidPeso molecular:320.39MLN8054 sodium
CAS:MLN8054 sodium is an Aurora A inhibitor.Fórmula:C25H14ClF2N4NaO2Cor e Forma:SolidPeso molecular:498.84
