Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2441 produtos de "Cromatina/Epigenética"
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Acefylline piperazine
CAS:Acefylline piperazine, a less toxic theophylline derivative, treats asthma and bronchitis by bronchodilation, stimulating respiration and CNS.Fórmula:C9H10N4O4·xC4H10N2Cor e Forma:SolidPeso molecular:562.54KDM2B-IN-3
CAS:KDM2B-IN-3, from patent WO2016112284A1 as compound 183c, potently inhibits histone demethylase KDM2B, with cancer research potential.Fórmula:C25H30N2O2Cor e Forma:SolidPeso molecular:390.521,2-Didecanoylglycerol
CAS:1,2-Didecanoylglycerol has functions as bioregulator of protein kinase C in human platelets.Fórmula:C23H44O5Cor e Forma:SolidPeso molecular:400.59Galegine hydrochloride
CAS:Galegine hydrochloride, from G. officinalis, leads to weight loss, activates AMPK in various cells, and has antibacterial properties.Fórmula:C6H14ClN3Cor e Forma:SolidPeso molecular:163.65SIRT2-IN-11
CAS:SIRT2-IN-11 (AEM1), a SIRT2 inhibitor (IC50 18.5μM), induces apoptosis and affects p53, used in cancer research.Fórmula:C21H22N2OCor e Forma:SolidPeso molecular:318.41HIF-1/2α-IN-2
CAS:HIF-1/2α-IN-2 is a potent inhibitor of HIF-1/2α, which effectively reduces the levels of HIF-1/2α.Fórmula:C16H11FN4O2SCor e Forma:SolidPeso molecular:342.35Thi-DPPY
CAS:Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.Fórmula:C28H28ClN5O4SCor e Forma:SolidPeso molecular:566.07CM-579
CAS:CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.Fórmula:C29H40N4O3Pureza:99.23%Cor e Forma:SolidPeso molecular:492.65Ref: TM-T10840L
1mg55,00€5mg96,00€10mg138,00€25mg217,00€50mg319,00€100mg472,00€1mL*10mM (DMSO)124,00€Peficitinib hydrobromide
CAS:Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.Fórmula:C18H23BrN4O2Cor e Forma:SolidPeso molecular:407.312M133
CAS:M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.Fórmula:C23H24N4OS2Cor e Forma:SolidPeso molecular:436.59Bizine
CAS:Bizine, a Phenelzine analogue, selectively inhibits LSD1 (Ki=59 nM), modulates histone methylation in cancer, and may have neuroprotective uses.Fórmula:C18H23N3OCor e Forma:SolidPeso molecular:297.39Y08284
CAS:Y08284: selective CBP bromodomain inhibitor, IC50: 4.21 nM, oral. Halts prostate cancer cell growth; anti-tumor.Fórmula:C26H25FN4O4Cor e Forma:SolidPeso molecular:476.5HIF-PHD-IN-2
CAS:HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].Fórmula:C17H15N5O3SCor e Forma:SolidPeso molecular:369.4Rucaparib camsylate
CAS:Rucaparib camsylate, a PARP-1, -2, -3 inhibitor (Ki=1.4 nM for PARP-1) & H6PD blocker, may treat resistant prostate cancer.Fórmula:C19H18FN3O·xC10H16O4SCor e Forma:SolidMT477
CAS:MT477 inhibits PKC-α, impairs Ras/ERK1/2 phosphorylation, induces apoptosis, and reduces proliferation in various cancer cells.Fórmula:C31H30N2O12S3Cor e Forma:SolidPeso molecular:718.77Aurora kinase inhibitor-10
CAS:Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.Fórmula:C21H19F5N6O4SCor e Forma:SolidPeso molecular:546.47HDAC-IN-29
CAS:HDAC-IN-29 (compound 13b) is a potent pan- HDAC inhibitor with antitumor activity.Fórmula:C20H23N3O4SCor e Forma:SolidPeso molecular:401.48PF-739
CAS:PF-739 is an AMPK agonist that has been shown to activate AMPK in hepatocytes and skeletal muscle.Fórmula:C23H23ClN2O5Pureza:98%Cor e Forma:SolidPeso molecular:442.89HIF-1α-IN-3
CAS:<p>HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].</p>Fórmula:C19H17N5O2Cor e Forma:SolidPeso molecular:347.37NVS-BET-1
CAS:NVS-BET-1 is a BET bromodomain inhibitor. NVS-BET-1 can regulate keratinocyte plasticity.Fórmula:C22H21ClN4O2Cor e Forma:SolidPeso molecular:408.88
