Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2548 produtos de "Cromatina/Epigenética"
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KR-39038
CAS:KR-39038 is an oral GRK5 inhibitor for heart failure research; blocks HDAC5 pathway, IC50: 0.02 μM, fights cardiac hypertrophy.Fórmula:C24H32ClFN6OCor e Forma:SolidPeso molecular:475.00I-BET787
CAS:I-BET787, an orally active pan-BET bromodomain inhibitor, has demonstrated efficacy in murine inflammation models.Fórmula:C16H20ClN3O2Cor e Forma:SolidPeso molecular:321.80KAT6-IN-1
CAS:KAT6-IN-1 (compound E) is a selective, orally available inhibitor of histone acetyltransferases KAT6A and KAT6B, exhibiting antitumour activity for cancer.Fórmula:C19H18N4O5SPureza:99.86%Cor e Forma:SolidPeso molecular:414.43MY-1B
CAS:MY-1B is a nitrogen-substituted butenamide stereoprobe that blocks stereoselective enrichment of NSUN2, binding selectively to the C271 of NSUN2.Fórmula:C22H18BrN3O2Pureza:99.81% - >99.99%Cor e Forma:SoildPeso molecular:436.3TMPA
CAS:TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.Fórmula:C21H32O6Pureza:99.21%Cor e Forma:SolidPeso molecular:380.48Ref: TM-T13173
1mg75,00€5mg164,00€10mg260,00€25mg440,00€50mg620,00€100mg964,00€1mL*10mM (DMSO)167,00€GSK-1268997
CAS:GSK-1268997 is a bio-active chemical.Fórmula:C21H23N7O3SPureza:99.33% - 99.81%Cor e Forma:SolidPeso molecular:453.52UNC0224
CAS:UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.Fórmula:C26H43N7O2Pureza:99.80%Cor e Forma:SolidPeso molecular:485.67Ref: TM-T17203
1mg51,00€2mg73,00€5mg97,00€10mg159,00€25mg354,00€50mg558,00€100mg797,00€500mg1.634,00€1mL*10mM (DMSO)107,00€Phorbol 12,13-dibutyrate
CAS:Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Fórmula:C28H40O8Pureza:99.32% - 99.37%Cor e Forma:SolidPeso molecular:504.61Ref: TM-T16526
1mg58,00€5mg160,00€10mg268,00€25mg530,00€50mg827,00€100mg1.314,00€200mg1.773,00€1mL*10mM (DMSO)170,00€E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Fórmula:C21H30O6Pureza:99.52%Cor e Forma:SolidPeso molecular:378.46TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Fórmula:C26H25ClF3N5O3Pureza:99.73%Cor e Forma:SolidPeso molecular:547.96Ref: TM-T6039
1mg38,00€5mg80,00€10mg120,00€25mg216,00€50mg354,00€100mg512,00€200mg727,00€1mL*10mM (DMSO)96,00€GW843682X
CAS:GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).Fórmula:C22H18F3N3O4SPureza:99.92%Cor e Forma:SolidPeso molecular:477.46HDAC-IN-45
CAS:HDAC-IN-45, a small HDAC blocker, forms H-bonds with Y303 and shows anticancer properties; IC50 for HDAC1/2/3: 0.108/0.585/0.563 μM.Fórmula:C25H20ClFN8OCor e Forma:SolidPeso molecular:502.93Kgp-IN-1
CAS:Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.Fórmula:C19H24F4N4O3Pureza:98%Cor e Forma:SolidPeso molecular:432.41Y02224
CAS:Y02224 is a BET inhibitor. It shows the reasonable antiproliferative effect on leukemia cells.Fórmula:C20H17BrN2O4SPureza:98%Cor e Forma:SolidPeso molecular:461.33ITF3756
CAS:ITF3756 is a selective HDAC6 inhibitor.Fórmula:C13H11N5O2SPureza:97.74%Cor e Forma:SolidPeso molecular:301.32Farnesylthiotriazole
CAS:Farnesylthiotriazole is a persistent PKC activator agent.Fórmula:C17H27N3SPureza:98%Cor e Forma:SolidPeso molecular:305.48Tenovin-D3
CAS:Tenovin-D3 is a sirtuin SirT2 inhibitor. It acts by increasing p21 (CDKN1A) expression in a p53-independent manner.Fórmula:C22H27Cl3N4O3SPureza:98%Cor e Forma:SolidPeso molecular:533.9Dot1L-IN-5
CAS:Dot1L-IN-5 is a potent inhibitor of the disruptor of telomeric silencing 1-like protein ( DOT1L ) with an IC 50 SPA DOT1L of 0.17 nM [1].Fórmula:C23H19ClF2N8O5SCor e Forma:SolidPeso molecular:592.96Givinostat hydrochloride monohydrate
CAS:Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor.Fórmula:C24H27N3O4·HCl·H2OPureza:97.97% - 99.51%Cor e Forma:SolidPeso molecular:475.97ML399
CAS:ML399 inhibits menin–MLL interaction, selectively blocking oncogenic MLL signaling in leukemia cells, supporting functional genomics and therapeutic research.Fórmula:C27H28FN3O2Pureza:97.84% - 98.20%Cor e Forma:SolidPeso molecular:445.53
