Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2553 produtos de "Cromatina/Epigenética"
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DS-437
CAS:DS-437 is a dual PRMT5/7 inhibitor (IC50s: 6 μM). DS-437 also inhibits DNMT3A and DNMT3B (IC50s: 52 and 62 μM). DS-437 inhibits the methylation of FOXP3.Fórmula:C15H23N7O4SPureza:98%Cor e Forma:SolidPeso molecular:397.45SIRT5 inhibitor 2
CAS:SIRT5 inhibitor 2 (compound 49) has inhibitory activity through SIRT5-dependent deacetylation and cancer and neurodegenerative diseases.Fórmula:C18H12Cl2N2O3SPureza:99.38% - 99.87%Cor e Forma:SolidPeso molecular:407.27KBH-A42
CAS:KBH-A42 is an inhibitor of histone deacetylase.Fórmula:C17H22N2O3Pureza:98%Cor e Forma:SolidPeso molecular:302.37MI-1
CAS:MI-1 inhibits Menin-MLL interaction with an IC 50 of 1.9 μM [1].Fórmula:C19H25N5S2Cor e Forma:SolidPeso molecular:387.57Piribedil dihydrochloride
CAS:dopamine agonistFórmula:C16H20Cl2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:371.26Dot1L-IN-7
CAS:Dot1L-IN-7 (compound 25), a potent DOT1L inhibitor with an IC50 of 1.0 μM, selectively kills MLL-AF9, sparing E2A-HLF cells.Fórmula:C23H27N9O2Cor e Forma:SolidPeso molecular:461.52AMPK activator 12
CAS:AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein for cancer research.Fórmula:C23H24BrNO2Pureza:99.55%Cor e Forma:SolidPeso molecular:426.356-Methyl-5-azacytidine
CAS:6-Methyl-5-azacytidine is a potent DNMT inhibitor.Fórmula:C9H14N4O5Pureza:98%Cor e Forma:SolidPeso molecular:258.23LT052
CAS:LT052 is a BET BD1 inhibitor with anti-inflammatory activity. It mediates the BRD4/NF-κB/NLRP3 signaling inflammatory pathway.Fórmula:C22H19N5O4SPureza:98.82%Cor e Forma:SolidPeso molecular:449.48PI3K/HDAC-IN-1
CAS:PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively).
Fórmula:C22H25FN4O4Pureza:98%Cor e Forma:SolidPeso molecular:428.46BRD4 Inhibitor-19
CAS:BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma.Fórmula:C29H25N5O3Cor e Forma:SolidPeso molecular:491.54BRD4884
CAS:BRD4884 is a highly selective and efficient HDAC1 and HDAC2 inhibitor that also inhibits HDAC3, used in research on neurological disorders.Fórmula:C18H19FN2O2Pureza:99.19% - 99.21%Cor e Forma:SolidPeso molecular:314.35Lorpucitinib
CAS:Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal diseases.Fórmula:C22H28N6O2Pureza:99.72%Cor e Forma:SolidPeso molecular:408.5TK4g
CAS:TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) & 15.80 nM (JAK3); promising for lymphoid diseases & leukemia research.Fórmula:C19H19N3O4SCor e Forma:SolidPeso molecular:385.44INO-1001 methanesulfonate
CAS:INO-1001 methanesulfonate is a strong PARP inhibitor with chemosensitization and radiosensitization effects.Fórmula:C24H29N3O7S2Cor e Forma:SolidPeso molecular:535.63TyK2-IN-2
CAS:TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).Fórmula:C16H18N6OPureza:98%Cor e Forma:SolidPeso molecular:310.35(R)-BAY1238097
CAS:(R)-BAY1238097 is a selective inhibitor against the binding of BET proteins to histones, used in acute myeloid leukemia (AML) and multiple myeloma (MM) studies.Fórmula:C25H33N5O3Pureza:98.77%Cor e Forma:SolidPeso molecular:451.56Ref: TM-T13442
1mg49,00€5mg101,00€10mg172,00€25mg355,00€50mg620,00€100mg1.044,00€200mg1.404,00€1mL*10mM (DMSO)113,00€D 595
CAS:D595 is a phenethylamine-type calcium channel blocker. The most potent phenylethylamine with respect to negative inotropy was D595 (EC50: 794 nmol/l).Fórmula:C25H32Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:463.44CPI703
CAS:CPI703 is a novel potent and specific CBP/EP300 bromodomain inhibitor.Fórmula:C17H22N4OPureza:98%Cor e Forma:SolidPeso molecular:298.38UNC2327
CAS:UNC2327 is a potent and selective inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50:230 nM).Fórmula:C14H17N5O2SPureza:98%Cor e Forma:SolidPeso molecular:319.38
