DNA Metiltransferase
As metiltransferases de DNA (DNMTs) são enzimas que catalisam a adição de grupos metila a resíduos de citosina no DNA, levando ao silenciamento gênico. A metilação aberrante do DNA está associada a várias doenças, incluindo câncer. Inibidores de DNMT bloqueiam a atividade dessas enzimas, levando à reativação de genes silenciados e à indução de apoptose em células cancerígenas. Os inibidores de DNMT são amplamente utilizados em pesquisas epigenéticas e terapias contra o câncer. Na CymitQuimica, oferecemos uma gama de inibidores de DNMT de alta qualidade para apoiar sua pesquisa em epigenética, metilação de DNA e biologia do câncer.
Foram encontrados 455 produtos de "DNA Metiltransferase"
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Tazemetostat trihydrochloride
CAS:Tazemetostat trihydrochloride, an EZH2 inhibitor, orally active, IC50: 4nM (rat), Ki: 2.5nM (human), effective in peptide and nucleosome assays.Fórmula:C34H47Cl3N4O4Pureza:98%Cor e Forma:SolidPeso molecular:682.12Acedapsone
CAS:Acedapsone has antimalarial and antimicrobial action, but is mainly used as a depot leprostatic agent.Fórmula:C16H16N2O4SPureza:98%Cor e Forma:SolidPeso molecular:332.37GSK-1268997
CAS:GSK-1268997 is a bio-active chemical.Fórmula:C21H23N7O3SPureza:99.33% - 99.81%Cor e Forma:SolidPeso molecular:453.52UNC0224
CAS:UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.Fórmula:C26H43N7O2Pureza:99.80%Cor e Forma:SolidPeso molecular:485.67Ref: TM-T17203
1mg51,00€2mg73,00€5mg97,00€10mg159,00€25mg354,00€50mg558,00€100mg797,00€500mg1.634,00€1mL*10mM (DMSO)107,00€MY-1B
CAS:MY-1B is a nitrogen-substituted butenamide stereoprobe that blocks stereoselective enrichment of NSUN2, binding selectively to the C271 of NSUN2.Fórmula:C22H18BrN3O2Pureza:99.81% - >99.99%Cor e Forma:SoildPeso molecular:436.3ZLD10A
CAS:ZLD10A is a highly potent and selective small molecule inhibitor of EZH2.Fórmula:C37H48N4O4Pureza:98%Cor e Forma:SolidPeso molecular:612.8JS1310
CAS:JS1310 is a selective PRMT7 inhibitor (IC50: 5 μM against human PRMT7). JS1310 has shown anti-cancer effects on different cancer cells.Fórmula:C23H22FN5O3Cor e Forma:SolidPeso molecular:435.45JNJ-7925476 free base
CAS:JNJ-7925476 is an TRI antidepressant agent.Fórmula:C20H19NPureza:98%Cor e Forma:SolidPeso molecular:273.372′-Deoxy-5-nitrocytidine
CAS:2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].Fórmula:C9H12N4O6Cor e Forma:SolidPeso molecular:272.21LEM-14-1189
CAS:LEM-14-1189 inhibits NSD1/2/3 (IC50: 418/111/60 μM), targets nuclear receptors, and may treat cancer and blood diseases.Fórmula:C35H34N6O5S2Pureza:98.06%Cor e Forma:SolidPeso molecular:682.81S-Aristeromycinylhomocysteine
CAS:S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.Fórmula:C15H22N6O4SCor e Forma:SolidPeso molecular:382.44EPZ033294
CAS:EPZ033294 has potential anticancer and antiproliferative activity.Fórmula:C20H22ClN7OPureza:99.95%Cor e Forma:SolidPeso molecular:411.89DM-01
CAS:<p>DM-01 is a potent and selective inhibitor of EZH2.</p>Fórmula:C23H24F3N3O2Cor e Forma:SolidPeso molecular:431.45DCE_254
CAS:DCE_254 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Fórmula:C21H17N9OSPureza:98%Cor e Forma:SolidPeso molecular:443.48Setin-1
CAS:Setin-1 is the most potent Set7 inhibitor that acts by inhibiting the KMTase G9a.Fórmula:C29H21F3N2O2Pureza:98%Cor e Forma:SolidPeso molecular:486.48Prospasmine
CAS:Prospasmine is an anticholinergic.Fórmula:C17H28ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:313.87ML399
CAS:ML399 inhibits menin–MLL interaction, selectively blocking oncogenic MLL signaling in leukemia cells, supporting functional genomics and therapeutic research.Fórmula:C27H28FN3O2Pureza:97.84% - 98.20%Cor e Forma:SolidPeso molecular:445.53Ref: TM-T24484
1mgA consultar5mg730,00€10mgA consultar25mg1.539,00€50mg1.941,00€100mg2.451,00€150mg2.565,00€DC_501
CAS:DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.Fórmula:C25H23Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:452.38OTS186935 trihydrochloride
CAS:OTS186935 trihydrochloride is a protein methyltransferase inhibitor of SUV39H2(IC50 of 6.49 nM).Fórmula:C25H29Cl4N5O2Pureza:98%Cor e Forma:SolidPeso molecular:573.34BAY-6035-R-isomer
CAS:BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.Fórmula:C22H28N4O3Cor e Forma:SolidPeso molecular:396.48
