DNA Metiltransferase
As metiltransferases de DNA (DNMTs) são enzimas que catalisam a adição de grupos metila a resíduos de citosina no DNA, levando ao silenciamento gênico. A metilação aberrante do DNA está associada a várias doenças, incluindo câncer. Inibidores de DNMT bloqueiam a atividade dessas enzimas, levando à reativação de genes silenciados e à indução de apoptose em células cancerígenas. Os inibidores de DNMT são amplamente utilizados em pesquisas epigenéticas e terapias contra o câncer. Na CymitQuimica, oferecemos uma gama de inibidores de DNMT de alta qualidade para apoiar sua pesquisa em epigenética, metilação de DNA e biologia do câncer.
Foram encontrados 457 produtos de "DNA Metiltransferase"
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Prospasmine
CAS:Prospasmine is an anticholinergic.Fórmula:C17H28ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:313.87Setin-1
CAS:Setin-1 is the most potent Set7 inhibitor that acts by inhibiting the KMTase G9a.Fórmula:C29H21F3N2O2Pureza:98%Cor e Forma:SolidPeso molecular:486.48DCE_254
CAS:DCE_254 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Fórmula:C21H17N9OSPureza:98%Cor e Forma:SolidPeso molecular:443.48GSK926
CAS:GSK926 is a selective, SAM-competitive, and cell-active EZH2 inhibitor.Fórmula:C29H35N7O2Cor e Forma:SolidPeso molecular:513.63Arazine
CAS:Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.Fórmula:C20H33NO3SPureza:90%Cor e Forma:SolidPeso molecular:367.55JNJ-7925476 free base
CAS:JNJ-7925476 is an TRI antidepressant agent.Fórmula:C20H19NPureza:98%Cor e Forma:SolidPeso molecular:273.37(R)-OR-S1
CAS:(R)-OR-S1 is a SAM-competitive, highly selective, orally bioavailable dual inhibitor of EZH1/2.Fórmula:C26H34BrN3O4Pureza:98%Cor e Forma:SolidPeso molecular:532.47MS453
CAS:MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.Fórmula:C20H27N5O3Cor e Forma:SolidPeso molecular:385.46S-Aristeromycinylhomocysteine
CAS:S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.Fórmula:C15H22N6O4SCor e Forma:SolidPeso molecular:382.44ZLD10A
CAS:ZLD10A is a highly potent and selective small molecule inhibitor of EZH2.Fórmula:C37H48N4O4Pureza:98%Cor e Forma:SolidPeso molecular:612.8LEM-14-1189
CAS:LEM-14-1189 inhibits NSD1/2/3 (IC50: 418/111/60 μM), targets nuclear receptors, and may treat cancer and blood diseases.Fórmula:C35H34N6O5S2Pureza:98.06%Cor e Forma:SolidPeso molecular:682.81PRMT5:MEP50 PPI
PRMT5:MEP50 PPI inhibitor with anti-tumor and anti-proliferative effects on lung and prostate cancers.Fórmula:C24H22N4O4Cor e Forma:SolidPeso molecular:430.46CSV0C018875 Hydrochloride
CAS:CSV0C018875 Hydrochloride: Novel G9a inhibitor with low toxicity, effective in enzyme/cell assays, outperforms BIX-0129.Fórmula:C18H18Cl2N2OCor e Forma:SolidPeso molecular:349.255D 595
CAS:D595 is a phenethylamine-type calcium channel blocker. The most potent phenylethylamine with respect to negative inotropy was D595 (EC50: 794 nmol/l).Fórmula:C25H32Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:463.44EPZ033294
CAS:EPZ033294 has potential anticancer and antiproliferative activity.Fórmula:C20H22ClN7OPureza:99.95%Cor e Forma:SolidPeso molecular:411.89BAY-6035-R-isomer
CAS:BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.Fórmula:C22H28N4O3Cor e Forma:SolidPeso molecular:396.48Valemetostat tosylate
CAS:Valemetostat tosylate is a dual inhibitor of EZH1/2 and used in the research of relapsed/refractory peripheral T-cell lymphoma.Fórmula:C33H42ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:660.22MM-102
CAS:MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.Fórmula:C35H49F2N7O4Pureza:98.77% - 99.99%Cor e Forma:SolidPeso molecular:669.8Ref: TM-T6333
1mg39,00€2mg51,00€5mg105,00€10mg168,00€25mg351,00€50mg543,00€100mg777,00€1mL*10mM (DMSO)156,00€EPZ032597
CAS:EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and prevent and treat pancreatic cancerFórmula:C20H23N7OPureza:99.70%Cor e Forma:SolidPeso molecular:377.44PRMT4-IN-1
CAS:PRMT4-IN-1 is a selective inhibitor of PRMT4, demonstrating an IC50 value of 3.2 nM, and has been shown to reduce the relative viability of MCF7 cells [1].Fórmula:C23H28FN3OPureza:98%Cor e Forma:SolidPeso molecular:381.49
