Receptor de hormónio tireoidiano (THR)
Os receptores de hormônio tireoidiano (THR) são receptores nucleares que mediam os efeitos dos hormônios tireoidianos, que são críticos para a regulação do metabolismo, crescimento e desenvolvimento. A modulação da atividade dos THR é importante no tratamento de distúrbios da tireoide, síndromes metabólicas e certos tipos de câncer. Agonistas e antagonistas de THR são usados em pesquisas para estudar os papéis fisiológicos e patológicos dos hormônios tireoidianos. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de hormônio tireoidiano de alta qualidade para apoiar sua pesquisa em endocrinologia, metabolismo e regulação hormonal.
Foram encontrados 39 produtos para "Receptor de hormónio tireoidiano (THR)".
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PCO371
CAS:PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-Fórmula:C29H32F3N5O6SPureza:98% - 99.25%Cor e Forma:SolidPeso molecular:635.65Ref: TM-T16442
1mg63,00€5mg137,00€1mL*10mM (DMSO)178,00€10mg197,00€25mg356,00€50mg505,00€100mg715,00€3,5-Diiodothyropropionic acid
CAS:3,5-Diiodothyropropionic acid: thyroid hormone analog, boosts α-myosin mRNA, binds TRα1 & TRβ1 (Ka: 2.40/M, 4.06/M).Fórmula:C15H12I2O4Pureza:98.42%Cor e Forma:SolidPeso molecular:510.06pTH-Related Protein (7-34) amide (human, mouse, rat)
CAS:PTH-Related Protein (7-34) amide (human, mouse, rat) serves as a potent antagonist of parathyroid hormone (PTH) [1].Fórmula:C153H247N49O37Peso molecular:3364.9NH-3
CAS:NH-3, an orally active THR antagonist with a 55 nM IC50, blocks thyroid hormone binding and cofactor recruitment.Fórmula:C28H27NO6Pureza:97.79% - 99.40%Cor e Forma:SolidPeso molecular:473.52Ref: TM-T40548
1mg207,00€1mL*10mM (DMSO)467,00€5mg520,00€10mg750,00€25mg1.144,00€50mg1.521,00€100mg2.062,00€500mg4.159,00€Parathyroid hormone (1-34) (rat)
CAS:Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.Fórmula:C180H291N55O48S2Pureza:98%Cor e Forma:SolidPeso molecular:4057.74DPC-AJ1951
CAS:Potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM).Fórmula:C76H127N23O19Pureza:98%Cor e Forma:SolidPeso molecular:1666.98Prepro-TRH-(160-169)
CAS:Prepro-TRH-(160-169), a pro-TRH peptide, enhances TRH-stimulated TSH secretion.Fórmula:C54H75N11O18SCor e Forma:SolidPeso molecular:1198.3THR-β agonist 2 diacetate
THR-β agonist 2 diacetate (Compound 3) is a potent THR-β agonist with potential applications in researching metabolic disorders such as obesity, hyperlipidemia, hypercholesterolemia, and diabetes, as well as other conditions like steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis, and other related diseases and conditions.Cor e Forma:Odour SolidOsteostatin
CAS:Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presentingFórmula:C27H41N9O8Cor e Forma:SolidPeso molecular:619.67DPC-AJ1951 TFA
DPC-AJ1951 TFA is a 14 amino acid peptide, potent PTH/PPR agonist, tested in bone resorption assays.Fórmula:C78H128F3N23O21Cor e Forma:SolidPeso molecular:1781.02Calcitonin, eel
CAS:Calcitonin from eel regulates calcium and is key in studying postmenopausal osteoporosis.Fórmula:C146H241N43O47S2Pureza:98%Cor e Forma:SolidPeso molecular:3414.91pTH-Related Protein (1-34) amide (human, mouse, rat)
CAS:Human PTHrP-(1-34)NH2, also known as PTH-Related Protein (1-34) amide for human, mouse, and rat, is the N-terminal fragment of PTHrP.Cor e Forma:SolidHuman PTHrP-(1-36)
CAS:Human PTHrP-(1-36) is a secreted form of parathyroid hormone-related protein that exhibits anticalciuric effects and promotes beta cell function andFórmula:C191H305N59O52Cor e Forma:SolidPeso molecular:4259.83Trh-gly
CAS:TRH-glycine (TRH-gly) serves as a precursor to thyrotropin-releasing hormone (TRH), capable of inducing the release of thyrotropin (TSH) and prolactin [1].Fórmula:C18H24N6O6Cor e Forma:SolidPeso molecular:420.42Human PTH-(1-31) amide
CAS:Human PTH-(1-31) amide, an analog of PTH, effectively stimulates phosphatidylcholine hydrolysis and promotes the release of adenylyl cyclase [1].Fórmula:C162H270N50O46S2Cor e Forma:SolidPeso molecular:3718.31Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)
CAS:Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat), also known as Human PTHrP (107-111) amide, is a C-terminal fragment of parathyroidFórmula:C27H42N10O7Cor e Forma:SolidPeso molecular:618.69pTH (1-37) (human)
CAS:pTH (1-37) human fragment boosts cAMP, alkaline phosphatase, growth, and BMD, potential for osteoporosis research.Fórmula:C195H316N58O54S2Cor e Forma:SolidPeso molecular:4401.08(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)
CAS:'(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat), a peptide, functions as a ligand for parathyroid hormone (PTH) receptors [1].'Fórmula:C194H303N59O53Cor e Forma:SolidPeso molecular:4309.85Parathyroid Hormone (1-34), bovine
CAS:Parathyroid Hormone (1-34), bovine is a PTH receptor agonist used to study osteoporosis and hypoparathyroidism.Fórmula:C183H288N54O50S2Pureza:99.72%Cor e Forma:SolidPeso molecular:4104.39THR-β agonist 10
THR-β agonist 10 is an orally active and selective THR-β agonist with an EC50 value of 11 nM. It effectively lowers levels of ALT (alanine aminotransferase), TC (total cholesterol), and LDL-C (low-density lipoprotein cholesterol). In mouse models of metabolic dysfunction-associated steatohepatitis (MASH), it improves steatosis, ballooning, inflammation, and fibrosis. THR-β agonist 10 is utilized in the research of MASH.
