RAAS
Os inibidores do sistema renina-angiotensina-aldosterona (RAAS) são compostos que têm como alvo a via RAAS, conhecida principalmente por seu papel na regulação da pressão arterial e do equilíbrio de fluidos, mas que também influencia a angiogênese. A via RAAS pode contribuir para o desenvolvimento de novos vasos sanguíneos em tumores, apoiando assim seu crescimento. Inibir componentes do RAAS pode, portanto, ter efeitos antiangiogênicos, tornando esses inibidores valiosos no tratamento de certos tipos de câncer e distúrbios vasculares. Na CymitQuimica, oferecemos uma gama de inibidores de alta qualidade do RAAS para apoiar sua pesquisa em biologia cardiovascular, oncologia e angiogênese.
Foram encontrados 89 produtos de "RAAS"
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Pomisartan 2HCl
<p>Pomisartan 2HCl (BIBR363 2HCL) is a small molecule AT1R antagonist used to study heart failure and hypertension.</p>Fórmula:C31H32Cl2N4O2Pureza:99.88%Cor e Forma:SoildPeso molecular:563.52Zansecimab
CAS:<p>Zansecimab (LY-3127804) is a monoclonal antibody targeting angiopoietin 2 (Ang 2) for the study of cardiovascular and immune diseases.</p>Pureza:97.8% (SDS-PAGE); 99.7% (SEC-HPLC) - 97.8% (SDS-PAGE); 99.7% (SEC-HPLC)Cor e Forma:LiquidLosartan potassium
CAS:Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to theFórmula:C22H22ClKN6OPureza:99.9% - >99.99%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:461.01Olmesartan Medoxomil
CAS:Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.Fórmula:C29H30N6O6Pureza:99.89% - 99.9%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:558.59Ref: TM-T1518
5mg34,00€10mg50,00€25mg57,00€50mg63,00€100mg93,00€200mg137,00€500mg260,00€1mL*10mM (DMSO)55,00€Losartan
CAS:Losartan (DuP-753) is an angiotensin II receptor antagonist.Fórmula:C22H23ClN6OPureza:99.48% - >99.99%Cor e Forma:Off White Solid PowderPeso molecular:422.91CGP-42112 acetate
CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.Fórmula:C54H73N13O13Pureza:99.06% - 99.92%Cor e Forma:SoildPeso molecular:1112.24Ref: TM-T14939L
1mg93,00€5mg279,00€10mg403,00€25mg623,00€50mg837,00€100mg1.108,00€200mg1.504,00€1mL*10mM (DMSO)622,00€TRV055 acetate
TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.Fórmula:C44H61N9O11Pureza:99.84%Cor e Forma:SolidPeso molecular:892.01Ref: TM-T40220L
1mg109,00€2mg154,00€5mg235,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€200mg1.333,00€1mL*10mM (DMSO)389,00€Alunacedase alfa
CAS:Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.Pureza:99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:85.03 kDa[Sar1, Ile8]-Angiotensin II
CAS:[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.Fórmula:C46H73N13O10Pureza:98%Cor e Forma:SolidPeso molecular:968.15[Sar1, Ile8]-Angiotensin II acetate
'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.Fórmula:C48H77N13O12Pureza:99.36%Cor e Forma:SolidPeso molecular:1028.2Ref: TM-T7575L1
2mg34,00€5mg46,00€10mg60,00€25mg119,00€50mg192,00€100mg289,00€200mg415,00€1mL*10mM (DMSO)90,00€Handle region peptide, rat
CAS:Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.Fórmula:C54H101N15O12SPureza:98%Cor e Forma:SolidPeso molecular:1184.54Azilsartan Medoxomil Potassium
CAS:Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.Fórmula:C30H23N4O8·KPureza:99.99%Cor e Forma:SolidPeso molecular:606.62[Sar1, Ile8]-Angiotensin II TFA
[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.Fórmula:C48H74F3N13O12Pureza:98%Cor e Forma:SolidPeso molecular:1082.18Angiotensin II (1-4), human TFA
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.Fórmula:C26H38F3N7O10Pureza:98%Cor e Forma:SolidPeso molecular:665.62Angiotensin II 5-valine
CAS:ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.Fórmula:C49H69N13O12Pureza:98%Cor e Forma:SolidPeso molecular:N/AAngiotensin amide
CAS:Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.Fórmula:C49H70N14O11Pureza:98%Cor e Forma:SolidPeso molecular:1031.17Aliskiren D6 Hydrochloride
CAS:Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).Fórmula:C30H54ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:594.26Brain Natriuretic Peptide (1-32), rat
CAS:Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.Fórmula:C146H239N47O44S3Pureza:98%Cor e Forma:SolidPeso molecular:3452.94Angiotensin II (5-8), human
CAS:Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin IIFórmula:C26H36N6O5Pureza:98%Cor e Forma:SolidPeso molecular:512.6Angiotensin II (1-4), human
CAS:Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Fórmula:C24H37N7O8Pureza:98%Cor e Forma:SolidPeso molecular:551.59Saralasin
CAS:Competitive non-selective angiotensin II antagonist.Fórmula:C42H65N13O10Pureza:98%Cor e Forma:PowderPeso molecular:912C-Type Natriuretic Peptide (1-53), human
CAS:CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.Fórmula:C251H417N81O71S3Pureza:98%Cor e Forma:SolidPeso molecular:5801.77TRV056
CAS:TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.Fórmula:C52H74N14O13Cor e Forma:SolidPeso molecular:1103.249Aclerastide
CAS:Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.Fórmula:C42H64N12O11Cor e Forma:SolidPeso molecular:913.03Eprosartan
CAS:Eprosartan is a selective AT1 receptor blocker with IC50s of 9.2 nM (rat) and 3.9 nM (human), used for hypertension.Fórmula:C23H24N2O4SPureza:99.99%Cor e Forma:SolidPeso molecular:424.51PRO20
<p>PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.</p>Cor e Forma:Odour SolidTetrahydro Aldosterone
CAS:<p>Tetrahydro Aldosterone is a steroidal compound that inhibits the adrenal angiotensin II receptor, with an IC50 of 10 μM.</p>Fórmula:C21H32O5Cor e Forma:SolidPeso molecular:364.48Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.Fórmula:C42H55F3N8O10Pureza:98%Cor e Forma:SolidPeso molecular:888.93Renin FRET Substrate I
CAS:Renin FRET Substrate I, designed for human renin, contains angiotensinogen's N-terminal cleavage site.Fórmula:C90H120N22O16SCor e Forma:SolidPeso molecular:1798.15BIBS 39
CAS:BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.Fórmula:C32H36N4O3Pureza:99.28%Cor e Forma:SolidPeso molecular:524.65A 779
CAS:A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.Fórmula:C39H60N12O11Pureza:98%Cor e Forma:SolidPeso molecular:872.97Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg
Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg is a fluorescent renin substrate based on the N-terminal tetrapeptide sequence of human angiotensinogen (hTDP).Fórmula:C129H179N37O24SPeso molecular:2662.36444Chymase
CAS:Chymase is a proteolytic enzyme predominantly found in mast cells (MC), fibroblasts, and vascular endothelial cells. It is released into the extracellular matrix in response to inflammatory signals, tissue damage, and cellular stress. Chymase also plays a role in the generation of angiotensin II (Ang II), making it significant for cardiovascular disease research.Nesvacumab
CAS:Nesvacumab (REGN910) is a fully human monoclonal antibody targeting Angiopoietin 2 (Ang2), which can be used for studying advanced solid tumors.Pureza:98.7% (SDS-PAGE); 95.7% (SEC-HPLC) - 99.11% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.84 kDaValsartan Methyl Ester
CAS:<p>Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.</p>Fórmula:C25H31N5O3Pureza:99.54%Cor e Forma:SolidPeso molecular:449.55Valsartan-d9
CAS:Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.Fórmula:C24H29N5O3Pureza:98%Cor e Forma:SolidPeso molecular:444.57Olmesartan-d4
CAS:Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.Fórmula:C24H26N6O3Pureza:98%Cor e Forma:SolidPeso molecular:450.53Angiotensin II (3-8), human
CAS:Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.Cor e Forma:SolidPD 123319 ditrifluoroacetate
CAS:PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.Fórmula:C35H34F6N4O7Pureza:98%Cor e Forma:SolidPeso molecular:736.66Candesartan-d4
CAS:Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.Fórmula:C24H20N6O3Pureza:98%Cor e Forma:SolidPeso molecular:444.48Azilsartan-d5
CAS:Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.Fórmula:C25H20N4O5Pureza:98%Cor e Forma:SolidPeso molecular:461.48Losartan (D4 Carboxylic Acid)
CAS:Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.Fórmula:C22H21ClN6O2Pureza:98%Cor e Forma:SolidPeso molecular:440.92Angiogenin (108-122)
CAS:Angiogenin (108-122) peptide treats cancer, infectious, fibrotic, inflammatory, neurodegenerative, autoimmune, and heart diseases.Fórmula:C78H125N25O23Cor e Forma:SolidPeso molecular:1780.98Olmesartan
CAS:Olmesartan (RNH 6270) is an Angiotensin II Type I receptor antagonist.Fórmula:C24H26N6O3Pureza:91.89% - 99.81%Cor e Forma:White To Beige Solid SolidPeso molecular:446.5Angiotensin 1/2 (5-7) acetate
Angiotensin 1/2 (5-7) acetate: a dipsogenic hormone peptide, sequence H2N-Ile-His-Pro-OH, from liver-produced angiotensinogen.Fórmula:C19H31N5O6Pureza:99.13%Cor e Forma:SolidPeso molecular:425.49Ref: TM-T22574L
1mg44,00€2mg55,00€5mg65,00€10mg95,00€25mg131,00€50mg190,00€100mg285,00€200mg429,00€500mg705,00€Angiotensin I/II (1-5)
CAS:Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II.Fórmula:C30H48N8O9Pureza:>99.99%Cor e Forma:SolidPeso molecular:664.75Saralasin acetate(34273-10-4 free base)
CAS:Saralasin acetate is a Non-selective angiotensin II antagonist.Fórmula:C44H71N13O13Pureza:99.74%Cor e Forma:SolidPeso molecular:990.11PD 123319
CAS:PD 123319 ((S)-(+)-PD 123319) is a potent, selective AT2 angiotensin II receptor antagonist.Fórmula:C31H32N4O3Pureza:98.61% - 99.65%Cor e Forma:SolidPeso molecular:508.61Ref: TM-T6067
2mg46,00€5mg81,00€10mg111,00€25mg220,00€50mg285,00€100mg370,00€200mg527,00€1mL*10mM (DMSO)94,00€Olodanrigan sodium
CAS:Olodanrigan sodium (EMA-401 sodium) is an AT2R antagonist, used for neurological disease research.Fórmula:C32H28NNaO5Pureza:98.14%Cor e Forma:SolidPeso molecular:529.56Olodanrigan
CAS:Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation.Fórmula:C32H29NO5Pureza:98.33%Cor e Forma:SolidPeso molecular:507.58
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