Enzima
Os inibidores de enzimas são moléculas que se ligam a enzimas e diminuem sua atividade. Esses inibidores são amplamente utilizados em pesquisas para estudar a cinética enzimática, regulação e o papel de enzimas específicas nas vias metabólicas. Os inibidores de enzimas também são cruciais no desenvolvimento de medicamentos, pois muitos agentes terapêuticos funcionam inibindo enzimas envolvidas em processos patológicos. Ao direcionar enzimas, esses inibidores podem modular vias bioquímicas e oferecer tratamentos potenciais para várias doenças. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de enzimas de alta qualidade para apoiar sua pesquisa em bioquímica, farmacologia e descoberta de medicamentos.
Subcategorias de "Enzima"
- Anidrase carbónica(177 produtos)
- Hidroxilase(30 produtos)
- MPO(2 produtos)
- Redutase(52 produtos)
- Tirosinase(67 produtos)
Foram encontrados 3586 produtos de "Enzima"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Methazolamide
CAS:<p>Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.</p>Fórmula:C5H8N4O3S2Pureza:99.31% - 99.77%Cor e Forma:Crystals From Water SolidPeso molecular:236.27Telotristat ethyl
CAS:<p>Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.</p>Fórmula:C27H26ClF3N6O3Pureza:98% - 99.89%Cor e Forma:White SolidPeso molecular:574.98ACT-678689
CAS:<p>ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].</p>Fórmula:C23H22ClFN6O4S2Pureza:99.46%Cor e Forma:SolidPeso molecular:565.04Brinzolamide
CAS:<p>Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.</p>Fórmula:C12H21N3O5S3Pureza:99.84% - >99.99%Cor e Forma:Crystalline SolidPeso molecular:383.51p-Ethynylphenylalanine hydrochloride
CAS:<p>p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].</p>Fórmula:C11H12ClNO2Pureza:99.03%Cor e Forma:SolidPeso molecular:225.67pNNP
CAS:<p>pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.</p>Fórmula:C6H6NO6PPureza:99.73%Cor e Forma:SolidPeso molecular:219.09Arbutin
CAS:<p>Arbutin, a bearberry extract, blocks melanin by inhibiting tyrosinase.</p>Fórmula:C12H16O7Pureza:99.58% - 99.93%Cor e Forma:Colorless Elongated Prisms From Moist Ethyl Acetate White PowderPeso molecular:272.255-Feruloylquinic acid
CAS:<p>5-Feruloylquinic acid, a potent Sirt1 activator, may aid in developing anti-aging drugs.</p>Fórmula:C17H20O9Pureza:99.03%Cor e Forma:SolidPeso molecular:368.34Flanvotumab
CAS:<p>Flanvotumab (IMC-20D7S) is a humanized antibody targeting TYRP1 with strong antitumor effects via NK cells and ADCC.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:145.42 kDaBenzthiazide
CAS:<p>Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.</p>Fórmula:C15H14ClN3O4S3Pureza:99.34% - 99.79%Cor e Forma:Crystals From Acetone SolidPeso molecular:431.94Fenclonine
CAS:<p>Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.</p>Fórmula:C9H10ClNO2Pureza:98.81% - >99.99%Cor e Forma:Crystals From Methanol White SolidPeso molecular:199.63Actarit
CAS:<p>Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.</p>Fórmula:C10H11NO3Pureza:99.64% - 99.74%Cor e Forma:White Or Off-White Crystal Or Crystalline SolidPeso molecular:193.2Topiramate
CAS:<p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>Fórmula:C12H21NO8SPureza:99.79% - 99.92%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:339.36Zonisamide
CAS:<p>Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.</p>Fórmula:C8H8N2O3SPureza:99.05% - 99.9%Cor e Forma:Off-White PowderPeso molecular:212.23Methocarbamol
CAS:<p>Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.</p>Fórmula:C11H15NO5Pureza:99.96%Cor e Forma:Crystals From Benzene SolidPeso molecular:241.24KW-2450 Formate
<p>KW-2450 Formate is an IGF-1R/IR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.</p>Fórmula:C29H31N5O5SPureza:99.28%Cor e Forma:SolidPeso molecular:561.65Tioxolone
CAS:<p>Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.</p>Fórmula:C7H4O3SPureza:97.79%Cor e Forma:Light Yellow To Beige PowderPeso molecular:168.174-Chlorosalicylic acid
CAS:<p>4-Chlorosalicylic acid (4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid) is antimicrobial compositions comprising a metal salt and a benzoic acid analog</p>Fórmula:C7H5ClO3Pureza:98.59%Cor e Forma:Off-White To Light Beige PowderPeso molecular:172.57Acipimox
CAS:<p>Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.</p>Fórmula:C6H6N2O3Pureza:98.98%Cor e Forma:Low Yellow Liquid Or CrystallinePeso molecular:154.12VM4-037
CAS:<p>VM4-037 is a PET imaging agent used for carbonic anhydrase IX.</p>Fórmula:C26H29FN6O7S2Cor e Forma:SolidPeso molecular:620.675,6-Dihydro-2H-pyran-2-one
CAS:<p>5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.</p>Fórmula:C5H6O2Cor e Forma:SolidPeso molecular:98.1Lysozyme, from chicken egg white
CAS:Pureza:≥ 20,000U/mgCor e Forma:White to off-white powderPeso molecular:-Carbonic anhydrase inhibitor 31
<p>Carbonic anhydrase inhibitor31 is an mtCA2 inhibitor (Ki: 5.2 nM) that can be used in antituberculosis research.</p>Fórmula:C24H20N6O5SCor e Forma:SolidPeso molecular:504.12159hCA/VEGFR-2-IN-4
<p>hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/</p>Fórmula:C22H23FN6O5SPureza:98%Cor e Forma:SolidPeso molecular:502.52Carbonic anhydrase inhibitor 30
<p>Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].</p>Fórmula:C23H22FN3O5SCor e Forma:SolidPeso molecular:471.12642hCAIX-IN-19
<p>hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/</p>Cor e Forma:Odour SolidhCAIX-IN-17
<p>hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.</p>Fórmula:C19H18N2O3SCor e Forma:SolidPeso molecular:354.42Carbonic anhydrase inhibitor 18
<p>Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.</p>Fórmula:C26H28N4O6S2Peso molecular:556.14503Carbonic anhydrase inhibitor 32
<p>Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.</p>Fórmula:C17H16N6O3SCor e Forma:SolidPeso molecular:384.41Dorzolamide
CAS:<p>Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.</p>Fórmula:C10H16N2O4S3Pureza:98%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:324.44β-Glucosidase, from almonds
CAS:Pureza:approx. 90% (biuret)Cor e Forma:White to pale yellow or beige powderPeso molecular:-hCAII-IN-8
CAS:<p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>Fórmula:C15H16N2O5SPureza:99.73%Cor e Forma:SoildPeso molecular:336.36Tyrosinase-IN-38
<p>Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.</p>Cor e Forma:Odour SolidTrypsin, bovine origin
CAS:Pureza:≥ 2000units/mg (USP)Cor e Forma:White or almost white crystalline powderPeso molecular:-(E)-Dehydrodiconiferyl alcohol
CAS:<p>(E)-Dehydrodiconiferyl alcohol inhibits hCA IX/XII enzymes and blocks NF-κB nuclear translocation in healing tissues.</p>Fórmula:C20H22O6Cor e Forma:SolidPeso molecular:358.39hCAIX/XII-IN-14
<p>hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.</p>Fórmula:C16H14F3N3O4SCor e Forma:SolidPeso molecular:401.36DOTA-XYIMSR-01
CAS:<p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>Fórmula:C61H88N16O22S2Cor e Forma:SolidPeso molecular:1461.57CAIX/CAXII-IN-4
<p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>Fórmula:C23H21N5O3SCor e Forma:SolidPeso molecular:447.51TPH1-IN-1
<p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>Fórmula:C21H18N6O4SCor e Forma:SolidPeso molecular:450.47Tyrosinase-IN-32
<p>Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.</p>Fórmula:C15H19NO3Cor e Forma:SolidPeso molecular:261.32hCA/VEGFR-2-IN-2
<p>Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and</p>Fórmula:C23H26N6O5SPureza:98%Cor e Forma:SolidPeso molecular:498.552-Methoxy-4-propylphenol
CAS:<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Fórmula:C10H14O2Cor e Forma:SolidPeso molecular:166.22CAIX Inhibitor S4
CAS:<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Fórmula:C15H17N3O4SPureza:99.07%Cor e Forma:SolidPeso molecular:335.38Peroxidase, from horseradish, approx. 200 U/mg
CAS:Pureza:≥ 150U/mgCor e Forma:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecular:-Proteinase K
CAS:Pureza:≥ 30units/mg (pH 7.5, 37°C, dried basis)Cor e Forma:White or almost white lyophilized powderPeso molecular:-Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:<p>Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect</p>Fórmula:C47H64N14O10Cor e Forma:SolidPeso molecular:985.1hCAII-IN-6
<p>"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."</p>Fórmula:C20H25N3O4SCor e Forma:SolidPeso molecular:403.5IOX2-NH2-1
CAS:<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Fórmula:C19H17N3O5Pureza:98.77% - 99.91%Cor e Forma:SoildPeso molecular:367.36hCAII-IN-7
<p>hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.</p>Fórmula:C20H25N3O4SCor e Forma:SolidPeso molecular:403.5DPP IV/hCA II-IN-1
CAS:<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Fórmula:C17H20N2O5SCor e Forma:SolidPeso molecular:364.42TPT-004
<p>TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating</p>Cor e Forma:Odour SolidTSPO/Carbonic Anhydrase Modulator 1
<p>TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.</p>Fórmula:C35H51N3O3Cor e Forma:SolidPeso molecular:561.798Chlorothiazide
CAS:<p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>Fórmula:C7H6ClN3O4S2Pureza:98.46% - 98.91%Cor e Forma:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecular:295.72Phenylsulfamide
CAS:<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Fórmula:C6H8N2O2SCor e Forma:SolidPeso molecular:172.2Calmodulin-dependent Protein Kinase II fragment 290-309
CAS:Fórmula:C103H185N31O24SPeso molecular:2273.83Acesulfame
CAS:<p>Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.</p>Fórmula:C4H5NO4SCor e Forma:SolidPeso molecular:163.15Pyrocatechol
CAS:<p>Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.</p>Fórmula:C6H6O2Cor e Forma:SolidPeso molecular:110.11Anhydrotetracycline hydrochloride
CAS:<p>Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.</p>Fórmula:C22H23ClN2O7Pureza:98.90%Cor e Forma:SolidPeso molecular:462.88hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Cor e Forma:Odour SolidCarbonic anhydrase inhibitor 29
<p>Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.</p>Cor e Forma:Odour SolidTyrosinase-IN-34
<p>Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.</p>Fórmula:C19H14BrClN4OCor e Forma:SolidPeso molecular:429.7CAIX/CAXII-IN-3
<p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>Cor e Forma:Odour SolidTyrosinase-IN-36
<p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>Cor e Forma:Odour SolidPeroxidase
CAS:Pureza:≥ 85units/mg (dry basis)Cor e Forma:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecular:-
![Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76347.webp&w=3840&q=75)
