Enzima
Os inibidores de enzimas são moléculas que se ligam a enzimas e diminuem sua atividade. Esses inibidores são amplamente utilizados em pesquisas para estudar a cinética enzimática, regulação e o papel de enzimas específicas nas vias metabólicas. Os inibidores de enzimas também são cruciais no desenvolvimento de medicamentos, pois muitos agentes terapêuticos funcionam inibindo enzimas envolvidas em processos patológicos. Ao direcionar enzimas, esses inibidores podem modular vias bioquímicas e oferecer tratamentos potenciais para várias doenças. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de enzimas de alta qualidade para apoiar sua pesquisa em bioquímica, farmacologia e descoberta de medicamentos.
Subcategorias de "Enzima"
- Anidrase carbónica(177 produtos)
- Hidroxilase(30 produtos)
- MPO(2 produtos)
- Redutase(52 produtos)
- Tirosinase(67 produtos)
Foram encontrados 3586 produtos de "Enzima"
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DOTA-XYIMSR-01
CAS:<p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>Fórmula:C61H88N16O22S2Cor e Forma:SolidPeso molecular:1461.57CAIX/CAXII-IN-4
<p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>Fórmula:C23H21N5O3SCor e Forma:SolidPeso molecular:447.51TPH1-IN-1
<p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>Fórmula:C21H18N6O4SCor e Forma:SolidPeso molecular:450.47Tyrosinase-IN-32
<p>Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.</p>Fórmula:C15H19NO3Cor e Forma:SolidPeso molecular:261.32hCA/VEGFR-2-IN-2
<p>Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and</p>Fórmula:C23H26N6O5SPureza:98%Cor e Forma:SolidPeso molecular:498.552-Methoxy-4-propylphenol
CAS:<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Fórmula:C10H14O2Cor e Forma:SolidPeso molecular:166.22CAIX Inhibitor S4
CAS:<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Fórmula:C15H17N3O4SPureza:99.07%Cor e Forma:SolidPeso molecular:335.38Peroxidase, from horseradish, approx. 200 U/mg
CAS:Pureza:≥ 150U/mgCor e Forma:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecular:-Proteinase K
CAS:Pureza:≥ 30units/mg (pH 7.5, 37°C, dried basis)Cor e Forma:White or almost white lyophilized powderPeso molecular:-Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:<p>Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect</p>Fórmula:C47H64N14O10Cor e Forma:SolidPeso molecular:985.1hCAII-IN-6
<p>"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."</p>Fórmula:C20H25N3O4SCor e Forma:SolidPeso molecular:403.5IOX2-NH2-1
CAS:<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Fórmula:C19H17N3O5Pureza:98.77% - 99.91%Cor e Forma:SoildPeso molecular:367.36hCAII-IN-7
<p>hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.</p>Fórmula:C20H25N3O4SCor e Forma:SolidPeso molecular:403.5DPP IV/hCA II-IN-1
CAS:<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Fórmula:C17H20N2O5SCor e Forma:SolidPeso molecular:364.42TPT-004
<p>TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating</p>Cor e Forma:Odour SolidTSPO/Carbonic Anhydrase Modulator 1
<p>TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.</p>Fórmula:C35H51N3O3Cor e Forma:SolidPeso molecular:561.798Chlorothiazide
CAS:<p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>Fórmula:C7H6ClN3O4S2Pureza:98.46% - 98.91%Cor e Forma:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecular:295.72Phenylsulfamide
CAS:<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Fórmula:C6H8N2O2SCor e Forma:SolidPeso molecular:172.2Calmodulin-dependent Protein Kinase II fragment 290-309
CAS:Fórmula:C103H185N31O24SPeso molecular:2273.83Acesulfame
CAS:<p>Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.</p>Fórmula:C4H5NO4SCor e Forma:SolidPeso molecular:163.15Pyrocatechol
CAS:<p>Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.</p>Fórmula:C6H6O2Cor e Forma:SolidPeso molecular:110.11Anhydrotetracycline hydrochloride
CAS:<p>Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.</p>Fórmula:C22H23ClN2O7Pureza:98.90%Cor e Forma:SolidPeso molecular:462.88hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Cor e Forma:Odour SolidCarbonic anhydrase inhibitor 29
<p>Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.</p>Cor e Forma:Odour SolidTyrosinase-IN-34
<p>Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.</p>Fórmula:C19H14BrClN4OCor e Forma:SolidPeso molecular:429.7CAIX/CAXII-IN-3
<p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>Cor e Forma:Odour SolidTyrosinase-IN-36
<p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>Cor e Forma:Odour SolidPeroxidase
CAS:Pureza:≥ 85units/mg (dry basis)Cor e Forma:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecular:-
![Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76347.webp&w=3840&q=75)
