NF-κB
O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.
Foram encontrados 387 produtos de "NF-κB"
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Tenuigenin
CAS:Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.Fórmula:C30H45ClO6Pureza:98.9% - 99.53%Cor e Forma:SolidPeso molecular:537.13Ref: TM-T3907
2mg34,00€5mg50,00€1mL*10mM (DMSO)63,00€10mg73,00€25mg105,00€50mg152,00€100mg215,00€200mg318,00€Tectochrysin
CAS:Tectochrysin: antioxidant, hinders ABCG2 transport, induces apoptosis in NSC-LC by blocking STAT3 and activating DR3/Fas.Fórmula:C16H12O4Pureza:99.26%Cor e Forma:SolidPeso molecular:268.26INH14
CAS:INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).Fórmula:C15H16N2OPureza:95.41%Cor e Forma:SolidPeso molecular:240.3Picroside II
CAS:Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.Fórmula:C23H28O13Pureza:98% - 99.83%Cor e Forma:SolidPeso molecular:512.46Phorbol 12-myristate 13-acetate
CAS:Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Fórmula:C36H56O8Pureza:98.55% - >99.99%Cor e Forma:White To Off-White SolidPeso molecular:616.83Handelin
CAS:Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.Fórmula:C32H40O8Pureza:99.02% - 99.345%Cor e Forma:SolidPeso molecular:552.66Sciadopitysin
CAS:Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.Fórmula:C33H24O10Pureza:98.67% - 99.17%Cor e Forma:SolidPeso molecular:580.54Ref: TM-T5S2129
1mg49,00€5mg89,00€1mL*10mM (DMSO)123,00€10mg154,00€25mg288,00€50mg432,00€100mg620,00€500mg1.279,00€Okanin
CAS:Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.Fórmula:C15H12O6Pureza:95.19% - 99.4%Cor e Forma:SolidPeso molecular:288.25Ref: TM-TN2008
1mg84,00€1mL*10mM (DMSO)207,00€5mg245,00€10mg295,00€25mg497,00€50mg710,00€100mg964,00€Schisantherin A
CAS:Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.Fórmula:C30H32O9Pureza:98% - 99.989Cor e Forma:SolidPeso molecular:536.57Esculentoside H
CAS:Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.Fórmula:C48H76O21Pureza:98.04% - 99.3%Cor e Forma:SolidPeso molecular:989.1Isoliquiritin apioside
CAS:Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.Fórmula:C26H30O13Pureza:98.84% - 99.27%Cor e Forma:SolidPeso molecular:550.51Ginsenoside Re
CAS:Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.Fórmula:C48H82O18Pureza:99.12% - >99.99%Cor e Forma:White PowderPeso molecular:947.15Ref: TM-T2872
2mg34,00€5mg48,00€10mg63,00€1mL*10mM (DMSO)65,00€25mg92,00€50mg138,00€100mg197,00€200mg290,00€Suberosin
CAS:Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.Fórmula:C15H16O3Pureza:97.08% - 99.26%Cor e Forma:SolidPeso molecular:244.29Ref: TM-T5795
2mg37,00€5mg54,00€1mL*10mM (DMSO)56,00€10mg93,00€25mg167,00€50mg241,00€100mg359,00€200mg525,00€NDMC101
CAS:NDMC101 suppresses dipeptidyl peptidase-IV, NFATc1, and NF-κB in human T cells, modulating immunity.Fórmula:C13H9ClFNO2Pureza:99.89%Cor e Forma:SolidPeso molecular:265.67BMS-345541 hydrochloride
CAS:BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).Fórmula:C14H18ClN5Pureza:99.13%Cor e Forma:SolidPeso molecular:291.78Ref: TM-T8542
1mg38,00€2mg50,00€1mL*10mM (DMSO)52,00€5mg82,00€10mg119,00€25mg212,00€50mg356,00€100mg533,00€NF-κΒ activator 2
CAS:NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM.Fórmula:C16H11FN2O3Pureza:98.12%Cor e Forma:SolidPeso molecular:298.27Ref: TM-T39924
1mg94,00€2mg136,00€5mg226,00€1mL*10mM (DMSO)249,00€10mg335,00€25mg538,00€50mg730,00€100mg938,00€Eurycomalactone
CAS:Eurycomalactone, from Eurycoma longifolia, inhibits NF-κB (IC50 0.5 μM), stops protein synthesis and cyclin D1, spares IκBα and IKK.Fórmula:C19H24O6Pureza:99.48% - 99.87%Cor e Forma:SolidPeso molecular:348.39JSH-23
CAS:JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 is an antioxidant. Cost effective and quality assured.Fórmula:C16H20N2Pureza:98.03% - 99.67%Cor e Forma:SolidPeso molecular:240.34Ref: TM-T1930
1mg40,00€2mg54,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg113,00€25mg177,00€50mg268,00€100mg408,00€GS143
CAS:GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.Fórmula:C28H19FN2O4Pureza:97.67%Cor e Forma:SolidPeso molecular:466.46Ref: TM-T25465
2mg35,00€5mg55,00€1mL*10mM (DMSO)57,00€10mg87,00€25mg161,00€50mg245,00€100mg358,00€200mg520,00€Isodeoxyelephantopin
CAS:Isodeoxyelephantopin can inhibit the growth of various tumor cells.Fórmula:C19H20O6Pureza:99.88%Cor e Forma:SolidPeso molecular:344.36
