CCR
Os receptores de quimiocinas C-C (CCRs) são um grupo de GPCRs que respondem às quimiocinas, moléculas de sinalização que orientam a migração de células imunológicas para locais de inflamação ou infecção. Os CCRs desempenham papéis cruciais nas respostas imunológicas, inflamação e no desenvolvimento de várias doenças, incluindo distúrbios autoimunes e câncer. A modulação da atividade dos CCRs está sendo explorada como uma estratégia terapêutica para condições como artrite reumatoide, esclerose múltipla e infecção pelo HIV. Na CymitQuimica, oferecemos uma gama de moduladores de CCR de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Foram encontrados 140 produtos de "CCR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Nifeviroc
CAS:Nifeviroc (TD-0232) is an orally active CCR5 antagonist, useful in HIV-1 infection research.Fórmula:C33H42N4O6Pureza:98.14%Cor e Forma:SolidPeso molecular:590.71CCR3 antagonist 2
CAS:CCR3 antagonist2 (example 66) is a CCR3 antagonist useful for researching inflammatory or allergic diseases, particularly those affecting the respiratory tract, such as inflammatory or obstructive airway conditions.Fórmula:C21H28ClN5O3Cor e Forma:SolidPeso molecular:433.93INCB-9471 dihydrochloride
CAS:INCB-9471 HCl: a potent CCR5 antagonist, blocks monocyte migration & HIV-1.Fórmula:C30H42Cl2F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:632.59TAK-661
CAS:TAK-661 is an inhibitor of eosinophil chemotaxis (eosinophil chemotaxis) that significantly alleviates late-phase bronchoconstriction while inhibiting the proliferation of eosinophils in bronchoalveolar lavage (BAL) and their infiltration into the airway walls.Fórmula:C13H21N5O3SCor e Forma:SolidPeso molecular:327.40Aplaviroc hydrochloride
CAS:Aplaviroc, a potent CCR5 inhibitor, binds selectively, blocking HIV entry and specific monoclonal antibody attachment in vitro.Fórmula:C33H44ClN3O6Cor e Forma:SolidPeso molecular:614.17PF-07054894
CAS:PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.Fórmula:C24H30N6O4Cor e Forma:SolidPeso molecular:466.53BMS-741672
CAS:BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.Fórmula:C25H33F3N6O2Cor e Forma:SolidPeso molecular:506.56CP-481715
CAS:CP 481715 is an effective selective CCR1 antagonist with potential therapeutic significance for inflammatory diseases.Fórmula:C26H31FN4O4Cor e Forma:SolidPeso molecular:482.55CCR1 antagonist 13
CAS:CCR1 antagonist13 is a selective small molecule antagonist of CCR1.Fórmula:C25H27ClFN3O4Cor e Forma:SolidPeso molecular:487.95CCR7 Ligand 1
CAS:CCR7-Cmp2105 is a thiadiazole-dioxide allosteric antagonist for CCR7 with a Kd of 3 nM and IC50 of 7.3 μM against arrestin binding.Fórmula:C22H29N5O5SCor e Forma:SolidPeso molecular:475.56BI 639667
CAS:BI 639667, an azaindazole-class compound, potently inhibits CCR1 (IC50=1.8 nM in calcium flux assays).Fórmula:C22H18FN5O3SPureza:99.86%Cor e Forma:SolidPeso molecular:451.47CXCR2/CCR7 antagonist-1
CAS:CXCR2/CCR7 antagonist-1 (compound 6) is a potent dual antagonist of CXCR2 and CCR7, with IC50 values of 0.0046 μM and 0.0014 μM, respectively. It is valuable for research in tumor metastasis and autoimmune diseases.Fórmula:C23H27N3O5Cor e Forma:SolidPeso molecular:425.48Aplaviroc
CAS:Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.Fórmula:C33H43N3O6Pureza:97.98% - 98.26%Cor e Forma:SolidPeso molecular:577.71CCR5 antagonist 1
CAS:CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.Fórmula:C39H46ClF2N5O3SPureza:98%Cor e Forma:SolidPeso molecular:738.33CCR1 antagonist 11 hydrochloride
Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.Cor e Forma:SolidOphiobolin C
CAS:inhibitor of human CCR5 binding to HIV-1 gp120Fórmula:C25H38O3Pureza:98%Cor e Forma:SolidPeso molecular:386.57CP-865569
CAS:CP-865569 is a CCR1 antagonist useful in the research of inflammatory and autoimmune diseases, including conditions such as rheumatoid arthritis and multiple sclerosis.Fórmula:C22H26ClFN2O5SCor e Forma:SolidPeso molecular:484.969AZD-5672
CAS:AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.Fórmula:C32H38F2N2O5S2Pureza:98.1%Cor e Forma:SolidPeso molecular:632.78Ref: TM-T30260
1mg192,00€5mg434,00€10mg610,00€25mg888,00€50mg1.243,00€100mg1.693,00€1mL*10mM (DMSO)530,00€GSK-3050002
GSK-3050002 (HGS-1035) is a humanized IgG1 antibody that targets and binds to CCL20. It holds potential for inflammation research. For isotype control, refer to Human IgG1 kappa, Isotype Control.
Cor e Forma:Odour LiquidBX471 hydrochloride
CAS:BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.Fórmula:C21H25Cl2FN4O3Pureza:98%Cor e Forma:SolidPeso molecular:471.35
