Nrf2
Nrf2 é um fator de transcrição que regula a expressão de proteínas antioxidantes e enzimas de desintoxicação, desempenhando um papel fundamental na defesa celular contra o estresse oxidativo e a inflamação. A ativação da sinalização Nrf2 oferece proteção contra várias doenças, incluindo câncer, neurodegeneração e distúrbios cardiovasculares. Os moduladores de Nrf2 estão sendo explorados por suas potenciais aplicações terapêuticas na redução de danos oxidativos e inflamação. Na CymitQuimica, oferecemos uma gama de moduladores da via Nrf2 de alta qualidade para apoiar sua pesquisa em estresse oxidativo, inflamação e prevenção de doenças.
Foram encontrados 82 produtos para "Nrf2".
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AEM1
CAS:AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.Fórmula:C20H14FN3O2SPureza:98.37% - 99.88%Cor e Forma:SolidPeso molecular:379.407AT 14 acetate
TAT 14 acetate, a 14-mer peptide, activates Nrf2, has anti-inflammatory effects, and targets Keap1 without altering Nrf2 mRNA.Fórmula:C139H234N48O41Pureza:96.9%Cor e Forma:SolidPeso molecular:3233.644-Octyl itaconate
CAS:4-Octyl Itaconate is a cell-permeable derivative of Itaconate, an anti-inflammatory metabolite.Fórmula:C13H22O4Pureza:99.3% - 99.94%Cor e Forma:SolidPeso molecular:242.31ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Fórmula:C23H22Cl2N2O3SPureza:98.42% - 99.55%Cor e Forma:SolidPeso molecular:477.4Ref: TM-T8970
1mg43,00€5mg85,00€1mL*10mM (DMSO)92,00€10mg110,00€25mg215,00€50mg334,00€100mg467,00€200mg672,00€Trilobatin
CAS:Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFórmula:C21H24O10Pureza:97.16%Cor e Forma:SolidPeso molecular:436.41Ref: TM-T2S0731
1mg50,00€5mg99,00€1mL*10mM (DMSO)109,00€10mg141,00€25mg260,00€50mg385,00€100mg557,00€200mg790,00€Brusatol
CAS:Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.Fórmula:C26H32O11Pureza:99.35% - 99.95%Cor e Forma:SolidPeso molecular:520.53Ref: TM-TQ0211
1mg37,00€5mg88,00€1mL*10mM (DMSO)102,00€10mg152,00€25mg295,00€50mg477,00€100mg677,00€200mg888,00€CBR-470-1
CAS:CBR-470-1 is a glycolytic phosphoglycerate kinase 1 inhibitor and Nrf2 activator that exhibits neuroprotective activity by activating the Keap1-Nrf2 cascade.Fórmula:C14H20ClNO4S2Pureza:98.87%Cor e Forma:SolidPeso molecular:365.9Nrf2 activator-5
CAS:Nrf2 activator-5 combats oxidative stress and inflammation in microglia, with potent antioxidant effects.Fórmula:C25H30Cl2O6Cor e Forma:SolidPeso molecular:497.41Keap1-Nrf2-IN-13
CAS:Keap1-Nrf2-IN-13 is a Keap1-Nrf2 PPI inhibitor (IC₅₀ = 0.15 µM) that binds Keap1 polar residues (Asn414, Arg415, Arg483, Gln530).Fórmula:C28H32N2O10S2Cor e Forma:SolidPeso molecular:620.69Keap1-Nrf2-IN-12
CAS:eap1-Nrf2-IN-12 is a potent inhibitor of Keap1-Nrf2 (IC50: 2.30 μM). eap1-Nrf2-IN-12 is metabolically stable in human liver microsomes.Fórmula:C26H28N2O10S2Cor e Forma:SolidPeso molecular:592.64MIND4-17
CAS:MIND4-17 activates NRF2 by binding Keap1 C151, blocking Keap1-Nrf2, stabilizes Nrf2, and promotes its nuclear entry, with strong antioxidant effects.Fórmula:C20H15N5O3SCor e Forma:SolidPeso molecular:405.43BPK-29
CAS:BPK-29 disrupts NR0B1 binding and modifies C274, inhibiting growth in KEAP1-mutant cancers.Fórmula:C26H32ClN3O3Pureza:98%Cor e Forma:SolidPeso molecular:470AI-3
CAS:Nrf2/Keap1 and Keap1/Cul3 interaction inhibitorFórmula:C11H13ClO3S2Pureza:98%Cor e Forma:SolidPeso molecular:292.8K67
CAS:K67 competitively inhibits the interaction between Nrf2-ETGE and Keap1 and can be used to study cancer.Fórmula:C29H30N2O7S2Pureza:98.43%Cor e Forma:Yellow SolidPeso molecular:582.69(+)-DHMEQ
CAS:(+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.Fórmula:C13H11NO5Cor e Forma:SolidPeso molecular:261.23WN1316
CAS:WN1316 is a unique neuroprotectant against oxidative injury, being a highly promising remedy for the treatment of amyotrophic lateral sclerosis (ALS).Fórmula:C20H26Cl3N5OCor e Forma:SolidPeso molecular:458.81MSU38225
CAS:MSU38225, an Nrf-2 inhibitor, elevates reactive oxygen species (ROS) levels and suppresses the proliferation of human lung cancer cells.Fórmula:C21H19N3Cor e Forma:SolidPeso molecular:313.4Nrf2-Activator-12G
CAS:Nrf2-Activator-12G is a potent Nrf-2 activator.Fórmula:C15H13ClO3SPureza:99.92%Cor e Forma:White SolidPeso molecular:308.78Dihydrolipoic acid
CAS:Dihydrolipoic acid (USAF XR-12), a dithiol carboxylic acid, is a potent antioxidant active against various reactive oxygen species at 0.01-0.5 mM.Fórmula:C8H16O2S2Pureza:97.51%Cor e Forma:Yellow To Orange LiquidPeso molecular:208.34Nrf2 activator-4
CAS:Nrf2 activator-4 is an Nrf2 activator for the treatment of fatty liver disease associated with metabolic dysfunction in humans.Fórmula:C23H24ClF3N2O3Pureza:98.53% - 98.89%Cor e Forma:SolidPeso molecular:468.9Ref: TM-T63016
10mgA consultar1mg54,00€5mg114,00€1mL*10mM (DMSO)118,00€25mg359,00€50mg532,00€100mg760,00€
