Nrf2
Nrf2 é um fator de transcrição que regula a expressão de proteínas antioxidantes e enzimas de desintoxicação, desempenhando um papel fundamental na defesa celular contra o estresse oxidativo e a inflamação. A ativação da sinalização Nrf2 oferece proteção contra várias doenças, incluindo câncer, neurodegeneração e distúrbios cardiovasculares. Os moduladores de Nrf2 estão sendo explorados por suas potenciais aplicações terapêuticas na redução de danos oxidativos e inflamação. Na CymitQuimica, oferecemos uma gama de moduladores da via Nrf2 de alta qualidade para apoiar sua pesquisa em estresse oxidativo, inflamação e prevenção de doenças.
Foram encontrados 81 produtos de "Nrf2"
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Fraxinellone analog 1
Fraxinellone analog 1 (compound 2) is an effective and rapid activator of the Nrf2-mediated antioxidative defense system, providing protection against glutamate-mediated excitotoxicity. It induces the expression of antioxidative genes Gpx4, Sod1, and Nqo1. Additionally, Fraxinellone analog 1 exerts neuroprotective effects and modulates oxidative stress and inflammation, making it suitable for research on neurodegenerative diseases.Cor e Forma:Odour SolidHis-Pro
CAS:His-Pro is a dipeptide consisting of histidyl and proline.Fórmula:C11H16N4O3Pureza:98%Cor e Forma:SolidPeso molecular:252.27Nrf2 activator-1
CAS:Nrf2 activator-1 activates Nrf2; used for COPD, asthma, ALI, ARDS, pulmonary fibrosis research.Fórmula:C30H34N4O6SPureza:97.8%Cor e Forma:SolidPeso molecular:578.68Butan-1-amine hydrochloride
CAS:1-Butylamine hydrochloride,butylamine, a potential agonist of Nrf2/ARE (Nuclear Factor Erythroid 2 Associated Factor 2/Antioxidant Response Element).Fórmula:C4H12ClNCor e Forma:SolidPeso molecular:109.6Pterisolic acid B
Pterisolic acid B is a useful organic compound for research related to life sciences and the catalog number is T125924.Fórmula:C20H26O4Cor e Forma:SolidPeso molecular:330.424TAT 14
CAS:TAT 14: a 14-mer peptide Nrf2 activator, anti-inflammatory, boosts Nrf2 protein, targets Keap1, no effect on mRNA.Fórmula:C137H230N48O39Pureza:98%Cor e Forma:SolidPeso molecular:3173.59TPNA10168
CAS:Compound Fr13590, with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13590 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C9H9ClO2S2Cor e Forma:SolidPeso molecular:248.75S217879
CAS:S217879 is a potent and selective activator of NRF2 that disrupts the KEAP1-NRF2 interaction, resulting in significant activation of the NRF2 pathway.Fórmula:C30H32N4O7SCor e Forma:SolidPeso molecular:592.67Keap1-Nrf2-IN-9
CAS:Keap1-Nrf2-IN-9 inhibits Keap1-Nrf2 PPI with 0.575 µM IC50, boosts Nrf2 genes, non-toxic in ARPE19 cells.Fórmula:C31H30N2O11S2Cor e Forma:SolidPeso molecular:670.71Ac-LDEETGEFL-NH2
CAS:Ac-LDEETGEFL-NH2 is a fluorescent molecule designed to target the interaction between the Kelch-like ECH-associated protein 1 (Keap1) and nuclear factorFórmula:C48H72N10O19Cor e Forma:SolidPeso molecular:1093.14CBR-470-2
CAS:CBR-470-2 activates NRF2 signaling, aiding in glycolysis research.Fórmula:C12H13Cl2NO6S2Cor e Forma:SolidPeso molecular:402.26Dimethyl fumarate-d6
CAS:Dimethyl fumarate D6 is a deuterium labeled Dimethyl fumarate. can induces upregulation of antioxidant gene expression.Fórmula:C6H8O4Pureza:98%Cor e Forma:SolidPeso molecular:150.16Anti-NFE2L2 Antibody (6K859)
Anti-NFE2L2 Antibody (6K859) is an antibody targeting NFE2L2. Anti-NFE2L2 Antibody (6K859) can be used in ELISA, IF.Cor e Forma:Odour LiquidAnti-Phospho-NFE2L2 (Ser40) Antibody (6V851)
Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) is an antibody targeting Phospho-NFE2L2 (Ser40). Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) can be used in ELISA, WB, IHC, IF.Cor e Forma:Odour LiquidAnti-NFE2L2 Antibody (9K94)
Anti-NFE2L2 Antibody (9K94) is a Mouse antibody targeting NFE2L2. Anti-NFE2L2 Antibody (9K94) can be used in ELISA, WB, IHC, IF, FCM.Pureza:>95%Cor e Forma:Odour LiquidI-152
CAS:Bepranemab (UCB 0107) is a humanized IgG monoclonal antibody against tau for the study of Alzheimer's disease (AD) and tau proteinopathies.Fórmula:C9H16N2O3S2Pureza:98.36%Cor e Forma:SolidPeso molecular:264.37ML334
CAS:ML334 (LH601A) is an NRF2 activator that inhibits cardiac fibroblast activation and proliferation ameliorating myocardial infarction-induced cardiac fibrosis.
Fórmula:C26H26N2O5Pureza:98.06% - 98.06%Cor e Forma:SolidPeso molecular:446.49KI696 isomer
CAS:KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.Fórmula:C28H30N4O6SPureza:99.8%Cor e Forma:SolidPeso molecular:550.63Ref: TM-T11758
1mg87,00€5mg264,00€1mL*10mM (DMSO)289,00€10mg442,00€25mg892,00€50mg1.198,00€100mg1.575,00€ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Fórmula:C23H22Cl2N2O3SPureza:98.42% - 99.55%Cor e Forma:SolidPeso molecular:477.4Ref: TM-T8970
1mg43,00€5mg85,00€1mL*10mM (DMSO)92,00€10mg110,00€25mg215,00€50mg334,00€100mg467,00€200mg672,00€Diroximel fumarate
CAS:Diroximel fumarate (Diroximel Fumarete), a prodrug of monomethyl fumarate in a controlled-release formulation, rapidly and potently converts to MMF in the body.Fórmula:C11H13NO6Pureza:99.8% - 99.88%Cor e Forma:SolidPeso molecular:255.22Ref: TM-T4271
2mg35,00€5mg55,00€1mL*10mM (DMSO)55,00€10mg80,00€25mg126,00€50mg187,00€100mg301,00€200mg425,00€
