Nrf2
Nrf2 é um fator de transcrição que regula a expressão de proteínas antioxidantes e enzimas de desintoxicação, desempenhando um papel fundamental na defesa celular contra o estresse oxidativo e a inflamação. A ativação da sinalização Nrf2 oferece proteção contra várias doenças, incluindo câncer, neurodegeneração e distúrbios cardiovasculares. Os moduladores de Nrf2 estão sendo explorados por suas potenciais aplicações terapêuticas na redução de danos oxidativos e inflamação. Na CymitQuimica, oferecemos uma gama de moduladores da via Nrf2 de alta qualidade para apoiar sua pesquisa em estresse oxidativo, inflamação e prevenção de doenças.
Foram encontrados 80 produtos para "Nrf2".
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TBE-31
CAS:TBE-31 is a highly potent activator of Nrf2, a liver carcinogenesis blocker and a potent phase 2 cytoprotective pathway inducer.Fórmula:C21H18N2O2Cor e Forma:SolidPeso molecular:330.38TPNA10168
CAS:TPNA10168 ,with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. TPNA10168 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C9H9ClO2S2Cor e Forma:SolidPeso molecular:248.75Nrf2 degrader 30
CAS:Nrf2 degrader 30 PROTAC inhibits Nrf2 ubiquitination and proteasomal degradation, enhancing activity for antioxidant and protective mechanisms。Fórmula:C42H41FN8O7SPureza:97.73% - 98.81%Cor e Forma:SolidPeso molecular:820.89Nrf2/HO-1 activator 3
Nrf2/HO-1 Activator 3 (Compound C3a) is an activator of the Nrf2 signaling pathway that facilitates the translocation of Nrf2 into the nucleus and enhances the expression of heme oxygenase-1 (HO-1). In H9c2 cardiomyocytes subjected to H2O2 or high glucose stimulation, Nrf2/HO-1 Activator 3 inhibits the excessive expression of ROS and MDA, suppressing cell viability and colony formation, thereby exhibiting antioxidant activity.Fórmula:C27H26N2O6Cor e Forma:SolidPeso molecular:474.51Butan-1-amine hydrochloride
CAS:1-Butylamine hydrochloride,butylamine, a potential agonist of Nrf2/ARE (Nuclear Factor Erythroid 2 Associated Factor 2/Antioxidant Response Element).Fórmula:C4H12ClNCor e Forma:SolidPeso molecular:109.6His-Pro
CAS:His-Pro is a dipeptide consisting of histidyl and proline.Fórmula:C11H16N4O3Pureza:98%Cor e Forma:SolidPeso molecular:252.2717-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
CAS:Aspirin-enhanced COX-2 metabolite of DHA, activates Nrf2 and PPARγ, inhibits inflammation, with EC50 ~200 nM, effective at 5-25 μM.Fórmula:C22H30O3Cor e Forma:SolidPeso molecular:342.479TAT 14
CAS:TAT 14: a 14-mer peptide Nrf2 activator, anti-inflammatory, boosts Nrf2 protein, targets Keap1, no effect on mRNA.Fórmula:C137H230N48O39Pureza:98%Cor e Forma:SolidPeso molecular:3173.59Nrf2 activator 18
Nrf2 activator 18 (Compound 11a) is an orally active activator of the Keap1/Nrf2/HO-1 signaling pathway, promoting Nrf2 nuclear translocation and enhancing antioxidant effects. It inhibits IL-6 release with an IC50 of 4.816 μM. In a mouse model of PM2.5-induced lung injury, Nrf2 activator 18 demonstrates anti-inflammatory activity.Fórmula:C23H24FN3OCor e Forma:SolidPeso molecular:377.45S217879
CAS:S217879 is a potent and selective activator of NRF2 that disrupts the KEAP1-NRF2 interaction, resulting in significant activation of the NRF2 pathway.Fórmula:C30H32N4O7SCor e Forma:SolidPeso molecular:592.67ML334
CAS:ML334 (LH601A) is an NRF2 activator that inhibits cardiac fibroblast activation and proliferation ameliorating myocardial infarction-induced cardiac fibrosis.Fórmula:C26H26N2O5Pureza:98.06% - 98.06%Cor e Forma:SolidPeso molecular:446.49KI696 isomer
CAS:KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.Fórmula:C28H30N4O6SPureza:99.98%Cor e Forma:White SolidPeso molecular:550.63Ref: TM-T11758
1mg87,00€5mg264,00€1mL*10mM (DMSO)289,00€10mg442,00€25mg892,00€50mg1.198,00€100mg1.575,00€I-152
CAS:Bepranemab (UCB 0107) is a humanized IgG monoclonal antibody against tau for the study of Alzheimer's disease (AD) and tau proteinopathies.Fórmula:C9H16N2O3S2Pureza:98.36%Cor e Forma:SolidPeso molecular:264.37Anti-NFE2L2 Antibody (9K94)
Anti-NFE2L2 Antibody (9K94) is a Mouse antibody targeting NFE2L2. Anti-NFE2L2 Antibody (9K94) can be used in ELISA, WB, IHC, IF, FCM.Pureza:>95%Cor e Forma:Odour LiquidAnti-Phospho-NFE2L2 (Ser40) Antibody (6V851)
Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) is an antibody targeting Phospho-NFE2L2 (Ser40). Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) can be used in ELISA, WB, IHC, IF.Cor e Forma:Odour LiquidAnti-NFE2L2 Antibody (6K859)
Anti-NFE2L2 Antibody (6K859) is an antibody targeting NFE2L2. Anti-NFE2L2 Antibody (6K859) can be used in ELISA, IF.Cor e Forma:Odour LiquidDimethyl fumarate-D6
CAS:Dimethyl fumarate-D6 is a deuterium labeled Dimethyl fumarate (T0492). can induces upregulation of antioxidant gene expression.Fórmula:C6H8O4Pureza:98%Cor e Forma:SolidPeso molecular:150.16CBR-470-2
CAS:CBR-470-2 activates NRF2 signaling, aiding in glycolysis research.Fórmula:C12H13Cl2NO6S2Cor e Forma:SolidPeso molecular:402.26Artemisitene
CAS:Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.Fórmula:C15H20O5Pureza:99.58%Cor e Forma:SolidPeso molecular:280.32Ref: TM-T21065
1mg89,00€5mg177,00€1mL*10mM (DMSO)203,00€10mg313,00€25mg530,00€50mg757,00€100mg1.044,00€Kinsenoside
CAS:Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.Fórmula:C10H16O8Pureza:99.2% - 99.92%Cor e Forma:SolidPeso molecular:264.23
