TLR
Os receptores Toll-like (TLRs) são uma classe de proteínas que desempenham um papel crítico no sistema imunológico inato ao reconhecer padrões moleculares associados a patógenos (PAMPs) e iniciar respostas imunes. Os TLRs estão envolvidos na detecção de uma ampla gama de patógenos, incluindo bactérias, vírus e fungos, e são essenciais para a ativação de vias de sinalização inflamatória. A desregulação da sinalização dos TLRs está associada a doenças inflamatórias crônicas, distúrbios autoimunes e câncer. Na CymitQuimica, oferecemos uma variedade de moduladores de TLR de alta qualidade para apoiar sua pesquisa em imunidade inata, inflamação e doenças infecciosas.
Foram encontrados 93 produtos para "TLR".
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TLR7/8 agonist 1 dihydrochloride
CAS:TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities.Fórmula:C22H27Cl2N5Pureza:98.33%Cor e Forma:SolidPeso molecular:432.389Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Fórmula:C33H40O19Pureza:98.78% - 99.96%Cor e Forma:White SolidPeso molecular:740.6593ODN 2216
CAS:ODN 2216: TLR9 agonist that boosts IFN-α/β, stimulates NK and T cells, and aids IFN-γ production via PBMCs.Cor e Forma:LiquidParidiprubart
CAS:Paridiprubart (NI-0101) is a humanised monoclonal antibody targeting TLR4, ameliorative effects in COVID-19 patients with ARDS and rheumatoid arthritis.Pureza:96.9% (SDS-PAGE); 98.5% (SEC-HPLC) - 96.9% (SDS-PAGE); 98.5% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:145.16 kDa (Predicted)IPH33
IPH33 is a human monoclonal antibody (mAb) targeting TLR3/CD283. It is useful for research in cancer and inflammation.Cor e Forma:Odour LiquidCNTO-3157
CNTO-3157 is a human IgG4 monoclonal antibody (mAb) targeting TLR3/CD283. It is applicable for research in asthma and ulcerative colitis.TLR7/8 agonist 6
CAS:TLR7/8 agonist 6 is a dual TLR7 and TLR8 activator used for antiviral and tumor immunotherapy research by triggering innate immune responses.Fórmula:C24H27N5O2Pureza:99.99%Cor e Forma:White SolidPeso molecular:417.5AXC-715 trihydrochloride
CAS:AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.Fórmula:C18H28Cl3N5Pureza:99.87% - 99.98%Cor e Forma:SolidPeso molecular:420.807TLR7 agonist 20
CAS:TLR7 agonist20 (compound 23) is an imidazoquinoline analogue. It acts as a potent and specific TLR7 agonist with an EC50 value of 0.23 μM for hTLR7. This compound exhibits strong adjuvant activity on spike antibody levels and induces a robust T helper cell 1 (Th1) response, increasing IgG2b and IgG2c alongside IgG1.Fórmula:C22H24N4OPeso molecular:360.45Anti-Human TLR3/CD283 Antibody (CNTO5429)
Anti-TLR3/CD283 Antibody (CNTO5429) is a functional neutralizing antibody against TLR3, inhibiting innate immune overactivation and significantly reducing tissue damage potential by blocking the pattern recognition receptor signaling axis.TLR7 agonist 1
CAS:TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).Fórmula:C21H25N5OPureza:98%Cor e Forma:SolidPeso molecular:363.4561Anti-Human Dectin-1 Antibody (2M24)
Anti-Dectin-1 Antibody (2M24) is a humanized IgG1 monoclonal antibody targeting Dectin-1.CL264
CAS:CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.Fórmula:C19H23N7O4Pureza:98.01% - 99.87%Cor e Forma:White SolidPeso molecular:413.4304AZD8848
CAS:AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.Fórmula:C29H43N7O5Cor e Forma:SolidPeso molecular:569.6956DSR-6434
CAS:DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.Fórmula:C19H28N8O2Pureza:99.78%Cor e Forma:SolidPeso molecular:400.48Rabeximod
CAS:Rabeximod, an immunomodulator, eases autoimmune diseases, inhibits arthritis, and aids brain recovery post-injury by blocking inflammation.Fórmula:C22H24ClN5OPureza:99.99%Cor e Forma:Yellow SolidPeso molecular:409.912TLR7/8-IN-1
CAS:TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.Fórmula:C29H40N8O2Pureza:99.99%Cor e Forma:White SolidPeso molecular:532.6803M62812
CAS:TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.Fórmula:C13H13Cl2N3OSPureza:99.07%Cor e Forma:SolidPeso molecular:330.233BBIQ
CAS:BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of 59.1Fórmula:C21H22N4Pureza:99.71%Cor e Forma:SolidPeso molecular:330.4262SM360320
CAS:SM360320 (CL-087) is a selective TLR7 agonist that blocks HCV replication in hepatocytes and aids immunology research.Fórmula:C15H17N5O3Pureza:99.13%Cor e Forma:SolidPeso molecular:315.3272
