CFTR
CFTR é uma proteína de canal de cloreto que regula o transporte de íons cloreto e bicarbonato através das membranas das células epiteliais, desempenhando um papel crucial na manutenção do equilíbrio de fluidos nos tecidos. As mutações no gene CFTR levam à fibrose cística, uma desordem genética caracterizada pela produção de muco espesso que pode obstruir as vias aéreas e levar a graves problemas respiratórios e digestivos. Na CymitQuimica, oferecemos uma seleção de moduladores de CFTR para apoiar sua pesquisa em fibrose cística, transporte de íons e distúrbios genéticos.
Foram encontrados 64 produtos de "CFTR"
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AF-2785
CAS:<p>In epididymal epithelial cells, AF-2785 inhibits cystic fibrosis transmembrane conductance regulator Cl(-) channels.</p>Fórmula:C17H12Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:347.2SRI-37240
CAS:<p>SRI-37240 suppresses CFTR nonsense mutations, aids in fixing premature termination codons, works with G418.</p>Fórmula:C24H23N3O2Pureza:98.73%Cor e Forma:SolidPeso molecular:385.46VRT-532
CAS:<p>VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects.</p>Fórmula:C16H14N2OPureza:99.88% - 99.93%Cor e Forma:SolidPeso molecular:250.3Bamocaftor
CAS:<p>Bamocaftor corrects CFTR in CF, restoring F508del-CFTR function, used with tezacaftor and VX-561 for F508del/MF patients.</p>Fórmula:C28H32F3N5O4SPureza:99.71%Cor e Forma:SolidPeso molecular:591.65Crinecerfont
CAS:<p>Crinecerfont (SSR-125543) is a CRF1 antagonist, useful in congenital adrenal hyperplasia research.</p>Fórmula:C27H28ClFN2OSPureza:98.01% - 98.55%Cor e Forma:SolidPeso molecular:483.04UCCF-853
CAS:<p>UCCF-853 是一种小分子 CFTR 调节剂，可用于研究囊性纤维化。</p>Fórmula:C14H8ClF3N2OPureza:99.82%Cor e Forma:SolidPeso molecular:312.67PG01
CAS:<p>PG01 is a potent CFTR Cl-channel potentiator, effective against ΔF508 (Ka 0.3 μM), and also against E193K, G970R and G551D (CFTR mutants), with Kd values of 0.</p>Fórmula:C28H29N3O2Pureza:99.87%Cor e Forma:SolidPeso molecular:439.55CFTR corrector 8
CAS:<p>CFTR corrector 8: potent for cystic fibrosis research, modulates CFTR protein.</p>Fórmula:C29H27F2NO7Pureza:99.57%Cor e Forma:SolidPeso molecular:539.52CFTR corrector 12
CAS:<p>CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3 and can be used to study cystic fibrosis.</p>Fórmula:C19H21ClN4O2S2Pureza:99.47%Cor e Forma:SolidPeso molecular:436.98CP 154526
CAS:<p>CRF1 receptor antagonist</p>Fórmula:C23H33ClN4Pureza:98%Cor e Forma:SolidPeso molecular:400.99DNDS
CAS:<p>DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).</p>Fórmula:C14H8N2Na2O10S2Pureza:99.92%Cor e Forma:Physical Description White Powder (Ntp 1992)Peso molecular:474.33(R)-Vanzacaftor
CAS:<p>(R)-Vanzacaftor ((R)-VX-121) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator [1].</p>Fórmula:C32H39N7O4SCor e Forma:SolidPeso molecular:617.76Chromanol 293B
CAS:slow delayed rectifier K+ current (IKs) blockerFórmula:C15H20N2O4SPureza:98%Cor e Forma:SolidPeso molecular:324.4BPO-27 racemate
CAS:<p>BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.</p>Fórmula:C26H18BrN3O6Pureza:97.67% - 98.86%Cor e Forma:SolidPeso molecular:548.34CRF1 receptor antagonist-1
CAS:<p>CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to congenital adrenal hyperplasia (CAH) [1].</p>Fórmula:C27H28ClFN2O2SPureza:98%Cor e Forma:SolidPeso molecular:499.04(R)-Elexacaftor
CAS:<p>(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.</p>Fórmula:C26H34F3N7O4SPureza:98.991%Cor e Forma:SolidPeso molecular:597.65CFTR corrector 6
CAS:<p>CFTR corrector 6, a potent CFTR potentiator, aids cystic fibrosis research and related disorders.</p>Fórmula:C22H13F4N9Cor e Forma:SolidPeso molecular:479.39CFTR corrector 4
CAS:<p>Potent, oral CFTR corrector 4 targets cystic fibrosis, increasing cell surface CFTR levels.</p>Fórmula:C29H27F2NO7Pureza:99.32%Cor e Forma:SolidPeso molecular:539.52CFTR corrector 15
CAS:<p>CFTR Corrector 15 (Compound 4172) serves as a corrector for cystic fibrosis transmembrane conductance regulator (CFTR). When used in combination with VX-809, it addresses the folding defects of F508del-CFTR. CFTR Corrector 15 is also applicable in the research of cystic fibrosis.</p>Fórmula:C24H22ClN5O2SCor e Forma:SolidPeso molecular:479.98CFTR corrector 17
CAS:<p>CFTRcorrector 17 (example 17) is a regulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It is utilized in the study of diseases mediated by CFTR.</p>Fórmula:C18H15FN2O2Cor e Forma:SolidPeso molecular:310.32
