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CFTR

CFTR

CFTR é uma proteína de canal de cloreto que regula o transporte de íons cloreto e bicarbonato através das membranas das células epiteliais, desempenhando um papel crucial na manutenção do equilíbrio de fluidos nos tecidos. As mutações no gene CFTR levam à fibrose cística, uma desordem genética caracterizada pela produção de muco espesso que pode obstruir as vias aéreas e levar a graves problemas respiratórios e digestivos. Na CymitQuimica, oferecemos uma seleção de moduladores de CFTR para apoiar sua pesquisa em fibrose cística, transporte de íons e distúrbios genéticos.

Foram encontrados 66 produtos de "CFTR"

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produtos por página.
  • Glibenclamide potassium

    CAS:
    Glibenclamide potassium, a more soluble form of Glibenclamide, exists as anhydrous and hydrate salts.
    Fórmula:C23H27ClKN3O5S
    Cor e Forma:Solid
    Peso molecular:532.09

    Ref: TM-T72272

    5g
    330,00€
    10g
    595,00€
  • Lumacaftor

    CAS:
    Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.
    Fórmula:C24H18F2N2O5
    Pureza:99.48% - 99.68%
    Cor e Forma:Solid
    Peso molecular:452.41

    Ref: TM-T2595

    5mg
    48,00€
    10mg
    63,00€
    25mg
    78,00€
    50mg
    92,00€
    100mg
    116,00€
    500mg
    281,00€
    1mL*10mM (DMSO)
    50,00€
  • IOWH-032

    CAS:
    IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.
    Fórmula:C22H15Br2N3O4
    Pureza:98.92% - ≥95%
    Cor e Forma:Solid
    Peso molecular:545.18

    Ref: TM-T2486

    10mg
    59,00€
    25mg
    93,00€
    50mg
    143,00€
    100mg
    216,00€
    1mL*10mM (DMSO)
    48,00€
  • KM11060

    CAS:
    KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma
    Fórmula:C19H17Cl2N3O2S
    Pureza:98.86%
    Cor e Forma:Solid
    Peso molecular:422.33

    Ref: TM-T3135

    5mg
    34,00€
    10mg
    52,00€
    25mg
    87,00€
    50mg
    127,00€
    100mg
    188,00€
    1mL*10mM (DMSO)
    35,00€
  • Icenticaftor

    CAS:
    Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.
    Fórmula:C12H13F6N3O3
    Pureza:99.76%
    Cor e Forma:Solid
    Peso molecular:361.24

    Ref: TM-T9499

    1mg
    152,00€
    5mg
    313,00€
    10mg
    469,00€
    25mg
    750,00€
    50mg
    1.054,00€
    100mg
    1.494,00€
    200mg
    2.025,00€
    1mL*10mM (DMSO)
    248,00€
  • Ataluren

    CAS:
    Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.
    Fórmula:C15H9FN2O3
    Pureza:99.16% - 99.84%
    Cor e Forma:Solid
    Peso molecular:284.24

    Ref: TM-T1805

    5mg
    35,00€
    10mg
    54,00€
    25mg
    88,00€
    50mg
    117,00€
    100mg
    178,00€
    200mg
    213,00€
    500mg
    359,00€
    1mL*10mM (DMSO)
    46,00€
  • PPQ-102

    CAS:
    PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).
    Fórmula:C26H22N4O3
    Pureza:98.80% - ≥95%
    Cor e Forma:Solid
    Peso molecular:438.48

    Ref: TM-T1874

    1mg
    38,00€
    5mg
    80,00€
    10mg
    128,00€
    25mg
    255,00€
    50mg
    442,00€
    100mg
    707,00€
    1mL*10mM (DMSO)
    88,00€
  • CFTR corrector 2

    CAS:
    CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.
    Fórmula:C27H23FN4O4
    Pureza:99.66%
    Cor e Forma:Solid
    Peso molecular:486.49

    Ref: TM-T5312

    2mg
    39,00€
    5mg
    58,00€
    10mg
    85,00€
    25mg
    156,00€
    50mg
    226,00€
    100mg
    335,00€
    200mg
    469,00€
    1mL*10mM (DMSO)
    63,00€
  • CFTR(inh)-172

    CAS:
    CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.
    Fórmula:C18H10F3NO3S2
    Pureza:98% - 99.72%
    Cor e Forma:Solid
    Peso molecular:409.4

    Ref: TM-T2355

    1mg
    35,00€
    2mg
    46,00€
    5mg
    66,00€
    10mg
    97,00€
    25mg
    188,00€
    50mg
    359,00€
    100mg
    530,00€
    1mL*10mM (DMSO)
    69,00€
  • Tezacaftor

    CAS:
    Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.
    Fórmula:C26H27F3N2O6
    Pureza:98.84% - >99.99%
    Cor e Forma:Solid
    Peso molecular:520.5

    Ref: TM-T2263

    1mg
    40,00€
    2mg
    52,00€
    5mg
    82,00€
    10mg
    123,00€
    25mg
    212,00€
    50mg
    343,00€
    100mg
    505,00€
    1mL*10mM (DMSO)
    88,00€
  • SRI-41315

    CAS:
    SRI-41315 is an eRF1 degrader that acts as a molecular glue at the ribosomal decoding center.SRI-41315 induces extended pauses at the termination codon.
    Fórmula:C22H19N3O2
    Pureza:99.87%
    Cor e Forma:Solid
    Peso molecular:357.41

    Ref: TM-T61306

    1mg
    49,00€
    5mg
    94,00€
    10mg
    152,00€
    25mg
    296,00€
    50mg
    478,00€
    100mg
    769,00€
    200mg
    1.063,00€
  • Steviol

    CAS:
    1.
    Fórmula:C20H30O3
    Pureza:98% - 99.92%
    Cor e Forma:Solid
    Peso molecular:318.45

    Ref: TM-T2S1837

    1mg
    49,00€
    5mg
    89,00€
    10mg
    154,00€
    25mg
    250,00€
    50mg
    371,00€
    100mg
    552,00€
    200mg
    785,00€
    1mL*10mM (DMSO)
    73,00€
  • SRI-37240

    CAS:
    SRI-37240 suppresses CFTR nonsense mutations, aids in fixing premature termination codons, works with G418.
    Fórmula:C24H23N3O2
    Pureza:98.73%
    Cor e Forma:Solid
    Peso molecular:385.46

    Ref: TM-T61702

    1mg
    42,00€
    5mg
    88,00€
    10mg
    127,00€
    25mg
    207,00€
    50mg
    309,00€
    1mL*10mM (DMSO)
    87,00€
  • CFTR corrector 9

    CAS:
    CFTR corrector 9 is a CF modulator used to research cystic fibrosis and related disorders.
    Fórmula:C16H14N2O4
    Pureza:99.75%
    Cor e Forma:Solid
    Peso molecular:298.29

    Ref: TM-T60653

    2mg
    39,00€
    5mg
    60,00€
    10mg
    96,00€
    25mg
    170,00€
    50mg
    253,00€
    100mg
    363,00€
    200mg
    510,00€
    1mL*10mM (DMSO)
    58,00€
  • Posenacaftor

    CAS:
    Posenacaftor (PTI-801) regulates CFTR protein for cystic fibrosis research.
    Fórmula:C27H27NO5
    Cor e Forma:Solid
    Peso molecular:445.51

    Ref: TM-T62630

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • Posenacaftor sodium

    CAS:
    Posenacaftor (PTI-801) sodium, a CFTR modulator for CF research, corrects CFTR protein folding and trafficking.
    Fórmula:C27H27NNaO5
    Cor e Forma:Solid
    Peso molecular:468.505

    Ref: TM-T36519

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Corrector C4

    CAS:
    Corrector C4, a corrector commonly used to study cystic fibrosis mutants, works by alleviating the interaction between CFTR transmembrane domain mutants and
    Fórmula:C21H17ClN4O2S2
    Pureza:99.98%
    Cor e Forma:Solid
    Peso molecular:456.97

    Ref: TM-T31014

    1mg
    185,00€
    5mg
    459,00€
    10mg
    657,00€
    25mg
    1.026,00€
    50mg
    1.415,00€
    100mg
    1.872,00€
    500mg
    3.734,00€
  • Galicaftor

    CAS:
    ABBV-2222 is a CFTR corrector which is studied for the treatment of cystic fibrosis (CF).
    Fórmula:C28H21F4NO7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:559.46

    Ref: TM-T22252

    25mg
    1.586,00€
    50mg
    2.072,00€
    100mg
    2.660,00€
  • (R)-Posenacaftor sodium

    CAS:
    (R)-Posenacaftor sodium is a modulator for correcting cystic fibrosis protein folding.
    Fórmula:C27H27NNaO5
    Cor e Forma:Solid
    Peso molecular:468.505

    Ref: TM-T35925

    25mg
    1.159,00€
    50mg
    1.510,00€
    100mg
    2.375,00€
  • GLPG-3221

    CAS:
    GLPG-3221, a potent oral CFTR corrector for cystic fibrosis treatment, has an EC50 of 105 nM.
    Fórmula:C30H37F3N2O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:578.62

    Ref: TM-T13704

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€