Canal TRP/TRPV
Os canais TRP (Potencial do Receptor Transitório), incluindo a subfamília TRPV, são um grupo de canais iônicos envolvidos em vários processos sensoriais, como sensação de temperatura, percepção da dor e osmorregulação. Os canais TRP são amplamente expressos em diferentes tecidos e desempenham um papel nas respostas fisiológicas aos estímulos ambientais. Os canais TRPV, em particular, estão envolvidos na detecção de mudanças de temperatura e estão implicados em condições como dor crônica, inflamação e câncer. Na CymitQuimica, oferecemos uma gama abrangente de moduladores de canais TRP/TRPV para apoiar sua pesquisa em biologia sensorial, manejo da dor e transdução de sinais.
Foram encontrados 97 produtos de "Canal TRP/TRPV"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
AC1903
CAS:AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.Fórmula:C19H17N3OPureza:98.45%Cor e Forma:SolidPeso molecular:303.36JNJ-28583113
CAS:JNJ-28583113 is a TRPM2 antagonist, inducing phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death.Fórmula:C19H21F3N2O2Pureza:98.57%Cor e Forma:SolidPeso molecular:366.38Ref: TM-T74779
1mg94,00€5mg193,00€1mL*10mM (DMSO)213,00€10mg241,00€25mg387,00€50mg591,00€100mg754,00€200mg1.046,00€SAR7334
CAS:SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).Fórmula:C21H22ClN3OPureza:99.62% - 99.71%Cor e Forma:SolidPeso molecular:367.87Ref: TM-T12849
1mg67,00€2mg88,00€5mg152,00€1mL*10mM (DMSO)166,00€10mg236,00€25mg295,00€50mg349,00€100mg439,00€200mg628,00€N-Oleoyl Valine
CAS:N-Oleoyl valine, an N-acyl amine, antagonizes TRPV3 for thermoregulation; rises post-cold exposure; elevates in mouse lung injury.Fórmula:C23H43NO3Cor e Forma:SolidPeso molecular:381.59TRPV4 agonist-1
CAS:TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).Fórmula:C25H23ClF2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:484.93AM12
CAS:AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).Fórmula:C15H9BrO5Pureza:98%Cor e Forma:SolidPeso molecular:349.13RN9893
CAS:RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.Fórmula:C21H23F3N4O5SPureza:99.99%Cor e Forma:SolidPeso molecular:500.49Asivatrep
CAS:Asivatrep (PAC14028) is a selective and potent antagonist of transient receptor potential vanilloid subtype 1 (TRPV1) for the study of atopic dermatitis.Fórmula:C21H22F5N3O3SPureza:95.13%Cor e Forma:SolidPeso molecular:491.48TRPC6-PAM-C20
CAS:TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, EC50: 2.37μM.Fórmula:C22H21NO4Pureza:98.16%Cor e Forma:SolidPeso molecular:363.41D-3263 hydrochloride
CAS:D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.
Fórmula:C21H32ClN3O3Pureza:99.93%Cor e Forma:SolidPeso molecular:409.95JYL 1421
CAS:JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).Fórmula:C20H26FN3O2S2Pureza:98.83%Cor e Forma:SolidPeso molecular:423.57Ref: TM-T15634
1mg66,00€1mL*10mM (DMSO)170,00€5mg177,00€10mg289,00€25mg580,00€50mg888,00€100mg1.414,00€200mg1.882,00€TRPV3 antagonist 74a
CAS:TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.Fórmula:C17H17F3N2O2Pureza:≥98.0%Cor e Forma:SolidPeso molecular:338.32TRPM4-IN-2
CAS:NBA, or TRPM4-IN-2, is a potent TRPM4 inhibitor with IC50 of 0.16 μM, used in prostate and colorectal cancer research.Fórmula:C19H14ClNO4Pureza:99.21%Cor e Forma:SolidPeso molecular:355.77GSK1702934A
CAS:GSK1702934A is a TRPC3 agonist with pro-arrhythmic and positive inotropic effects and is used in the study of diabetes mellitus.Fórmula:C22H25N3O2SPureza:98.15%Cor e Forma:SolidPeso molecular:395.52Pyr3
CAS:Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.Fórmula:C16H11Cl3F3N3O3Pureza:98.04%Cor e Forma:SolidPeso molecular:456.63Ref: TM-T16687
1mg34,00€2mg49,00€5mg73,00€1mL*10mM (DMSO)81,00€10mg92,00€25mg203,00€50mg344,00€100mg485,00€200mg700,00€500mg1.063,00€ABT 102
CAS:ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.Fórmula:C21H24N4OPureza:98.38% - 99.86%Cor e Forma:SolidPeso molecular:348.44Ref: TM-T29522
1mg109,00€5mg235,00€1mL*10mM (DMSO)245,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€200mg1.333,00€HC-070
CAS:HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).Fórmula:C22H20Cl2N4O4Pureza:98.48%Cor e Forma:SolidPeso molecular:475.32Ref: TM-T15465
1mg84,00€5mg160,00€1mL*10mM (DMSO)165,00€10mg236,00€25mg406,00€50mg572,00€100mg772,00€200mg1.035,00€Elismetrep
CAS:Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.Fórmula:C27H21F3N2O5SPureza:99.37% - 99.93%Cor e Forma:SolidPeso molecular:542.53Olvanil
CAS:Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.Fórmula:C26H43NO3Pureza:99.58%Cor e Forma:SolidPeso molecular:417.62Ref: TM-T23106
2mg34,00€5mg49,00€1mL*10mM (DMSO)50,00€10mg75,00€25mg145,00€50mg236,00€100mg385,00€200mg560,00€Mavatrep
CAS:Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.Fórmula:C25H21F3N2OPureza:98.51% - 99.31%Cor e Forma:SolidPeso molecular:422.44Ref: TM-T16014
1mg63,00€2mg90,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg385,00€50mg618,00€100mg888,00€200mg1.243,00€
