Canal de Sódio
Os canais de sódio são proteínas de membrana essenciais que permitem a passagem de íons de sódio (Na+) através da membrana celular, gerando e propagando sinais elétricos em neurônios, células musculares e outros tecidos excitáveis. Esses canais são vitais para a iniciação e condução de potenciais de ação, sendo cruciais em processos como a transmissão de impulsos nervosos, contração muscular e função cardíaca. A desregulação dos canais de sódio pode levar a distúrbios neurológicos, arritmias e condições de dor crônica. Na CymitQuimica, oferecemos uma variedade de moduladores de canais de sódio para apoiar sua pesquisa em neurobiologia, cardiologia e manejo da dor.
Foram encontrados 259 produtos de "Canal de Sódio"
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Halofuginone hydrobromide
CAS:Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.Fórmula:C16H17BrClN3O3·HBrPureza:97.01% - 99.73%Cor e Forma:SolidPeso molecular:495.59Ref: TM-T3524
1mg34,00€2mg49,00€5mg74,00€10mg106,00€25mg207,00€50mg310,00€100mg469,00€500mg897,00€1mL*10mM (DMSO)84,00€Nav1.7 inhibitor
CAS:Nav1.7 inhibitor is a Nav1.7 inhibitor for research in the field of pain and anesthesia.Fórmula:C15H11Cl3FNO4SPureza:97.52%Cor e Forma:SolidPeso molecular:426.68Ref: TM-T12184
1mg42,00€2mg55,00€5mg89,00€10mg135,00€25mg264,00€50mg423,00€100mg677,00€1mL*10mM (DMSO)87,00€Relutrigine
CAS:Relutrigine, Oral sodium current inhibitor, suppresses sustained INa (SCN8A mutations), reduces neuronal excitability, for anticonvulsant therapy.Fórmula:C15H11F6N5O2Pureza:99.68%Cor e Forma:SolidPeso molecular:407.27Ref: TM-T69652
1mg260,00€5mg650,00€10mg1.009,00€25mg1.504,00€50mg1.963,00€100mg2.520,00€1mL*10mM (DMSO)583,00€Nav1.1 activator 1
CAS:Nav1.1 activator 1, Selective Nav1.1 agonist, BBB permeable, increases current decay time, for central nervous system disorder research.Fórmula:C24H23F3N4OPureza:98%Cor e Forma:SolidPeso molecular:440.46Ref: TM-T12179
1mg92,00€5mg230,00€10mg356,00€25mg712,00€50mg1.108,00€100mg1.791,00€1mL*10mM (DMSO)272,00€GX-585
CAS:GX-585 is a novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2.Fórmula:C24H25Cl2FN4O3SPureza:99.02% - 99.03%Cor e Forma:SolidPeso molecular:539.45Phenamil
CAS:Phenamil is an inhibitor of epithelial sodium channels, activates the osteomorphin protein pathway to promote bone repair and induces significant fat formation.Fórmula:C12H12ClN7OPureza:99.07%Cor e Forma:SolidPeso molecular:305.72Silperisone HCl
CAS:Silperisone HCl is a muscle relaxant and vasodilator, treating myoclonus, hypertonia, dystonia, and myospasm by blocking Na+ and Ca2+ channels.Fórmula:C15H25ClFNSiPureza:99.97%Cor e Forma:SolidPeso molecular:301.9Elpetrigine
CAS:Elpetrigine (GW273293) is a potential sodium channel blocker with antiepileptic activity that can be used to study epilepsy.Fórmula:C10H7Cl3N4Pureza:99.04% - 99.43%Cor e Forma:SolidPeso molecular:289.55NaV1.2/1.6 channel blocker-1
CAS:NaV1.2/1.6 channel blocker-1 is a NaV1.2/1.6 channel blocker that inhibits rNaV1.6 and can be used to study generalised epilepsy and movement disorders.Fórmula:C14H14N2OSPureza:99.54%Cor e Forma:SolidPeso molecular:258.34NHE3-IN-1
CAS:NHE3-IN-1 是钠/质子交换剂 3 (NHE-3) 的抑制剂。Fórmula:C12H10ClN3SPureza:99.93%Cor e Forma:SolidPeso molecular:263.75TC-N 1752
CAS:TC-N 1752 is an orally active inhibitor of Nav1.7 channel with IC50 of 0.17 μM. TC-N 1752 shows analgesic activities.Fórmula:C25H27F3N6O3Pureza:99.71%Cor e Forma:SolidPeso molecular:516.52Ref: TM-T23439
1mg34,00€5mg75,00€10mg111,00€25mg245,00€50mg363,00€100mg515,00€200mg702,00€1mL*10mM (DMSO)84,00€KR-32568
CAS:KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM).Fórmula:C13H12FN3O2Pureza:99.91%Cor e Forma:SolidPeso molecular:261.25Ralitoline
CAS:Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity.Fórmula:C13H13ClN2O2SPureza:98.45%Cor e Forma:SolidPeso molecular:296.77Nisoxetine hydrochloride
CAS:Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitorFórmula:C17H21NO2·HClPureza:99.21%Cor e Forma:White SolidPeso molecular:307.826-Iodoamiloride
CAS:6-Iodoamiloride is a potent inhibitor of acid-sensing ion channel 1 (ASIC1), exhibiting an IC50 value of 88 nM.Fórmula:C6H8IN7OPureza:98%Cor e Forma:SolidPeso molecular:321.08SLC13A5-IN-1
CAS:SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).Fórmula:C19H19Cl3N2O3SPureza:99.67%Cor e Forma:SolidPeso molecular:461.79Ref: TM-T12931
1mg48,00€5mg92,00€10mg152,00€25mg268,00€50mg447,00€100mg623,00€200mg883,00€500mg1.305,00€1mL*10mM (DMSO)114,00€Aneratrigine
CAS:Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].Fórmula:C19H20ClF2N5O2S2Pureza:98%Cor e Forma:SolidPeso molecular:487.97PF 04531083
CAS:PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.Fórmula:C17H16ClN5O2Pureza:99.85%Cor e Forma:SolidPeso molecular:357.79(Rac)-AMG8379
CAS:(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.Fórmula:C25H16ClF2N3O5SPureza:99.6%Cor e Forma:SolidPeso molecular:543.93Ref: TM-T12655
1mg175,00€2mg264,00€5mg404,00€10mg592,00€25mg888,00€50mg1.243,00€100mg1.701,00€500mg3.402,00€1mL*10mM (DMSO)512,00€Co 102862
CAS:Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.Fórmula:C14H12FN3O2Pureza:99.82%Cor e Forma:SolidPeso molecular:273.26
