Canal de Sódio
Os canais de sódio são proteínas de membrana essenciais que permitem a passagem de íons de sódio (Na+) através da membrana celular, gerando e propagando sinais elétricos em neurônios, células musculares e outros tecidos excitáveis. Esses canais são vitais para a iniciação e condução de potenciais de ação, sendo cruciais em processos como a transmissão de impulsos nervosos, contração muscular e função cardíaca. A desregulação dos canais de sódio pode levar a distúrbios neurológicos, arritmias e condições de dor crônica. Na CymitQuimica, oferecemos uma variedade de moduladores de canais de sódio para apoiar sua pesquisa em neurobiologia, cardiologia e manejo da dor.
Foram encontrados 273 produtos para "Canal de Sódio".
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Sodium Channel inhibitor 2
CAS:Sodium Channel inhibitor 2 is a blocker of sodium channel.Fórmula:C26H25Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:466.4Halofuginone hydrobromide
CAS:Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.Fórmula:C16H17BrClN3O3·HBrPureza:97.01% - 99.73%Cor e Forma:SolidPeso molecular:495.59Ref: TM-T3524
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)84,00€10mg106,00€25mg207,00€50mg310,00€100mg469,00€500mg897,00€Carisbamate
CAS:CarisbAMate (JNJ-10234094, RWJ 333369, YKP-509) is an antiepileptic drug candidate.Fórmula:C9H10ClNO3Pureza:99.94%Cor e Forma:White SolidPeso molecular:215.63NAV26
CAS:NAV26 is a selective blocker of the Nav1.7 channel.Fórmula:C22H21F3N2O4Pureza:99.93%Cor e Forma:White SolidPeso molecular:434.41GX-585
CAS:GX-585 is a novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2.Fórmula:C24H25Cl2FN4O3SPureza:98.96% - 99.02%Cor e Forma:SolidPeso molecular:539.45GDC-0276
CAS:GDC-0276 is an orally active, selective, and potent NaV1.7 inhibitor that can be used for the study of pain-related diseases.Fórmula:C24H31FN2O4SPureza:98.94% - 99.77%Cor e Forma:White SolidPeso molecular:462.58Relutrigine
CAS:Relutrigine, Oral sodium current inhibitor, suppresses sustained INa (SCN8A mutations), reduces neuronal excitability, for anticonvulsant therapy.Fórmula:C15H11F6N5O2Pureza:99.68%Cor e Forma:Orange SolidPeso molecular:407.27Ref: TM-T69652
1mg260,00€1mL*10mM (DMSO)583,00€5mg650,00€10mg1.009,00€25mg1.504,00€50mg1.963,00€100mg2.520,00€Nav1.1 activator 1
CAS:Nav1.1 activator 1, Selective Nav1.1 agonist, BBB permeable, increases current decay time, for central nervous system disorder research.Fórmula:C24H23F3N4OPureza:99.99%Cor e Forma:White SolidPeso molecular:440.46Ref: TM-T12179
1mg92,00€5mg230,00€1mL*10mM (DMSO)251,00€10mg356,00€25mg712,00€50mg1.108,00€100mg1.791,00€GX-936
CAS:GX-936, Selective Nav1.7 inhibitor, binds activated VSD4 to oppose inactivation, for pain perception research.Fórmula:C24H20F3N7O3S2Pureza:98.04%Cor e Forma:SolidPeso molecular:575.59Nav1.7 inhibitor
CAS:Nav1.7 inhibitor is a Nav1.7 inhibitor for research in the field of pain and anesthesia.Fórmula:C15H11Cl3FNO4SPureza:97.52%Cor e Forma:SolidPeso molecular:426.68Ref: TM-T12184
1mg42,00€2mg55,00€1mL*10mM (DMSO)87,00€5mg89,00€10mg135,00€25mg264,00€50mg423,00€100mg677,00€PF 05089771 tosylate
CAS:PF-05089771 inhibits Nav1.7 channels (IC50: 11-33 nM), selective over Nav1.1-1.6/1.8, Ca+, K+ channels, TRPV1; 1000x affinity for half-inactivated state.Fórmula:C18H12Cl2FN5O3S2·C7H8O3SPureza:98.55%Cor e Forma:SolidPeso molecular:672.56(5R)-BW-4030W92
CAS:(5R)-BW-4030W92 is the R-type of BW-4030W92, the active enantiomer.Fórmula:C11H9Cl2FN4Pureza:98.27%Cor e Forma:White SolidPeso molecular:287.12DPI 201-106
CAS:DPI 201-106: cardioselective h1 Na channel inhibitor, enhances heart contraction, blocks potassium and calcium currents.Fórmula:C29H30N4O2Pureza:99.94%Cor e Forma:SolidPeso molecular:466.57ASG-5ME
ASG-5ME is a drug-antibody coupling targeting SLC44A4 that shows anti-tumor activity in xenograft models and may be used to study pancreatic and gastric cancer.Pureza:98.1% (SDS-PAGE); 98.5% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.5% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.5 kDaE 0747
CAS:E 0747 is an antiarrhythmic agent of class 1C type. E-0747 suppresses arrhythmia by inhibiting the Na channels of cardiac cells.Fórmula:C21H28ClN3O4Pureza:95.17%Cor e Forma:SolidPeso molecular:421.92ATX-II TFA
ATX-II TFA, a specific Na+ channel modulator toxin, is derived from the venom of the sea anemone (Anemonia sulcata).Pureza:98%Cor e Forma:Odour SolidKR-32568
CAS:KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM).Fórmula:C13H12FN3O2Pureza:99.91%Cor e Forma:SolidPeso molecular:261.25Nisoxetine hydrochloride
CAS:Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitorFórmula:C17H21NO2·HClPureza:99.21%Cor e Forma:White SolidPeso molecular:307.82Ralitoline
CAS:Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity.Fórmula:C13H13ClN2O2SPureza:98.45%Cor e Forma:SolidPeso molecular:296.77NHE3-IN-1
CAS:NHE3-IN-1 是钠/质子交换剂 3 (NHE-3) 的抑制剂。Fórmula:C12H10ClN3SPureza:99.93%Cor e Forma:White SolidPeso molecular:263.75
