Canais de Cálcio
Os canais de cálcio são proteínas de membrana que regulam o fluxo de íons de cálcio para dentro e fora das células, o que é essencial para várias funções celulares, incluindo a contração muscular, a liberação de neurotransmissores e a expressão gênica. A desregulação da atividade dos canais de cálcio está associada a condições como hipertensão, arritmias cardíacas e distúrbios neurológicos. Na CymitQuimica, oferecemos uma ampla seleção de moduladores de canais de cálcio para apoiar sua pesquisa em saúde cardiovascular, neurobiologia e transdução de sinais.
Foram encontrados 541 produtos de "Canais de Cálcio"
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Oxodipine
CAS:Oxodipine blocks rabbit aortic contraction and weakens rat cardiac force; reduces Ca currents in myocytes; side effects: mouse constipation, dog gum swelling.Fórmula:C19H21NO6Pureza:99.64%Cor e Forma:SolidPeso molecular:359.37O-Desmethylcarvedilol
CAS:O-Desmethylcarvedilol (Desmethylcarvedilol) is an active metabolite of Carvedilol, a non-selective β-adrenergic receptor (β-AR) antagonist. This compound inhibits store overload-induced calcium release in HEK293 cells expressing the RyR2 R4496C mutation (IC50= 7.62 µM). Additionally, O-Desmethylcarvedilol slows the increase in heart rate and prevents diastolic pressure reduction induced by Isoproterenol in conscious rabbits (ED50s = 32 and 5 µg/kg).Fórmula:C23H24N2O4Cor e Forma:SolidPeso molecular:392.45D-myo-Inositol-1,4,5-triphosphate trisodium
CAS:D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by phospholipase C-mediatedFórmula:C6H15Na3O15P3Pureza:98%Cor e Forma:SolidPeso molecular:489.06SB-237376
CAS:SB-237376 is a calcium and potassium channel antagonist used to treat cardiac arrhythmias.Fórmula:C20H25N3O5Pureza:98.88% - 99.81%Cor e Forma:SoildPeso molecular:387.43D-myo-Inositol-1,4,5-triphosphate tripotassium
CAS:D-myo-Inositol-1,4,5-triphosphate tripotassium is a second messenger in the intracellular signaling system that induces Ca2+ mobilization.Fórmula:C6H12K3O15P3Cor e Forma:SolidPeso molecular:534.37(R)-IDHP
CAS:(R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.Fórmula:C12H16O5Cor e Forma:SolidPeso molecular:240.25CALP3
CAS:Cell-permeable CaM agonist, binds EF-hand, activates phosphodiesterase without Ca2+, inhibits Ca2+ toxicity, IC50=33μM.Fórmula:C44H68N10O9Pureza:98%Cor e Forma:SolidPeso molecular:881.08GTx1-15
GTx1-15, an inhibitor cystine knot (ICK) peptide, antagonizes the voltage-dependent calcium channel Cav3.1, as well as voltage-dependent sodium channels Nav1.3Fórmula:C176H271N53O45S7Pureza:98%Cor e Forma:SolidPeso molecular:4073.82Calcium Channel antagonist 5
CAS:Calcium Channel antagonist5 (compound 32) is a calcium channel antagonist with a pIC50 of 5.50.Fórmula:C17H18N2O6Cor e Forma:SolidPeso molecular:346.34ω-Conotoxin MVIIC TFA
ω-Conotoxin MVIIC TFA is a peptide and neurotoxin blocks P-type and q-type voltage-sensitive neuronal Ca ++ channels (VGCCs) radiolabel immunoprecipitation.Fórmula:C106H178N40O32S7·C2HF3O2Cor e Forma:SolidPeso molecular:2863.27Cholecystokinin-J
CAS:Cholecystokinin-J can be used in cholecystography, radiomanometry and biliary cinematography.Fórmula:C49H66N6O16SCor e Forma:SolidPeso molecular:1027.142,4,6-Tri-tert-butylphenol
CAS:2,4,6-Tri-tert-butylphenol inhibits the Ca2+ ATPase activity of human red blood cell membranes and can be used in related research in the field of life sciences.Fórmula:C18H30OPureza:99.55%Cor e Forma:SolidPeso molecular:262.44Amlodipine aspartic acid impurity
CAS:Amlodipine aspartic acid: a calcium blocker with antihypertensive effects; contains specific impurities.Fórmula:C24H29ClN2O9Pureza:98%Cor e Forma:SolidPeso molecular:524.95Myomodulin
CAS:Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A theFórmula:C36H67N11O8S2Pureza:98%Cor e Forma:SolidPeso molecular:846.12ω-Conotoxin GVIA
CAS:Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.Fórmula:C120H182N38O43S6Pureza:98%Cor e Forma:SolidPeso molecular:3037O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine
CAS:O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine is a major metabolite of the calcium channel inhibitor amlodipine .1Fórmula:C20H20ClNO7Cor e Forma:SolidPeso molecular:421.83Linoleic Acid Amide
CAS:<p>Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.</p>Fórmula:C18H33NOPureza:98%Cor e Forma:SolidPeso molecular:279.46ILS-920
CAS:ILS-920, a Rapamycin analog, has reduced immunosuppression, enhanced neuroprotection, and preferentially binds FKBP52 and L-type VGCC β1.Fórmula:C57H86N2O14Pureza:98%Cor e Forma:SolidPeso molecular:1023.3Atagabalin HCl
CAS:Atagabalin HCl is a novel voltage-dependent calcium channel (VDCC) α2δ subunit (1 and 2) ligand that affects slow-wave sleep and can be used to treat insomnia.Fórmula:C10H20ClNO2Pureza:99.91% - ≥98%Cor e Forma:SoildPeso molecular:221.72PACAP-38 (31-38), human, mouse, rat
CAS:PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine productionFórmula:C47H83N17O11Pureza:98%Cor e Forma:SolidPeso molecular:1062.27Lyso-Globotriaosylceramide (d18:1)
CAS:Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.Fórmula:C36H67NO17Cor e Forma:SolidPeso molecular:785.922D-myo-Inositol-1,2-diphosphate (sodium salt)
CAS:Ins(1,2)P2, a less potent InsP isomer than Ins(1,4,5)P3, acts as a secondary messenger in cellular signal transmission.Fórmula:C6H12Na2O12P2Cor e Forma:SolidPeso molecular:384.08Cyclic ADP-ribose ammonium
cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.Cor e Forma:Liquid1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride
CAS:<p>1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride inhibits L amino acid transporter proteins and the α2δ subunit of voltage-gated calcium channels.1-(</p>Fórmula:C5H10ClNO2Pureza:>99.99%Cor e Forma:SolidPeso molecular:151.59Elgodipine
CAS:Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.Fórmula:C29H33FN2O6Pureza:99.84% - 99.98%Cor e Forma:SolidPeso molecular:524.58ProTx-I
CAS:<p>Selective blocker for CaV3.1 (IC50 = 0.2 μM), CaV3.2 (31.8 μM), also inhibits NaV1.8 and blocks KV2.1 channels.</p>Fórmula:C171H245N53O47S6Pureza:98%Cor e Forma:SolidPeso molecular:3987.51Cavα2δ-IN-1
CAS:Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a KiFórmula:C18H27N5OCor e Forma:SolidPeso molecular:329.448PD 0299685
CAS:PD 0299685 is a potent α2δ ligand of the Ca2+ channel for the treatment of interstitial cystitis.Fórmula:C10H21NO2Pureza:97.20%Cor e Forma:SoildPeso molecular:187.28BTT-266
CAS:<p>BTT-266 is a blocker of voltage-gated calcium channel for pain management.</p>Fórmula:C34H28N4O4Pureza:98.34%Cor e Forma:SolidPeso molecular:556.61Calcium Channel Compound Library
A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;Cor e Forma:Odour SolidRef: TM-L7200
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarNAADP sodium
NAADP sodium is a Ca2+ motor second messenger that targets Ca(2+) channels and can be used to study cancer and immune dysfunction.Fórmula:C21H27N6O18P3Cor e Forma:SolidPeso molecular:744.39PACAP-38 (31-38), human, mouse, rat TFA
PACAP-38 (31-38), human, mouse, rat (TFA) demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal.Fórmula:C49H84F3N17O13Pureza:98%Cor e Forma:SolidPeso molecular:1176.29Mipsagargin
CAS:Mipsagargin (G-202) is a new antibiotic that inhibits DNA biosynthesis.Fórmula:C66H100N6O27Pureza:98%Cor e Forma:SolidPeso molecular:1409.52Triphenylethylene
CAS:Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C20H16Cor e Forma:White PowderPeso molecular:256.34Calcium Channel antagonist 4
CAS:Calcium Channel antagonist 4 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).Fórmula:C23H26N2O4SPureza:98.53%Cor e Forma:SolidPeso molecular:426.53Ethacrynic acid D5
CAS:Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.Fórmula:C13H12Cl2O4Pureza:98%Cor e Forma:SolidPeso molecular:308.17Flosatidil
CAS:Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases,Fórmula:C26H34F3N3O3SPureza:99.87% - 99.99%Cor e Forma:SolidPeso molecular:525.631,4-Dihydropyridine
1,4-Dihydropyridine acts as an antagonist for calcium channels (calcium channel), specifically blocking the L-type calcium channels. This action reduces the influx of calcium ions into cardiac and vascular smooth muscle cells, consequently decreasing cardiac contractility and heart rate, dilating blood vessels, and lowering blood pressure.Fórmula:C12H17NO4Cor e Forma:SolidPeso molecular:239.27Flunarizine
CAS:Flunarizine is an orally administered peripheral vasodilator, a dual blocker of voltage-gated Na+/Ca2+ channels and a D2 dopamine receptor antagonist.Fórmula:C26H26F2N2Pureza:99.9%Cor e Forma:SolidPeso molecular:404.50Ziconotide
CAS:Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.Fórmula:C102H172N36O32S7Pureza:98%Cor e Forma:White PowderPeso molecular:2639.13ω-Agatoxin TK
CAS:<p>Selective blocker of CaV2.1 P/Q-type calcium channels.</p>Fórmula:C215H337N65O70S10Pureza:98%Cor e Forma:SolidPeso molecular:5273.02(±)5(6)-DiHETE
CAS:Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.472Budiodarone tartrate
CAS:Budiodarone tartrate (ATI-2042 tartrate) is an antiarrhythmic agent that inhibits calcium channels, and can be used in atrial fibrillation research.Fórmula:C31H37I2NO11Pureza:97.44%Cor e Forma:SolidPeso molecular:853.44Ref: TM-T74678
1mg170,00€5mg425,00€10mg688,00€25mg1.306,00€50mg2.039,00€100mg2.872,00€1mL*10mM (DMSO)661,00€Chlorocresol
CAS:Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.Fórmula:C7H7ClOCor e Forma:SolidPeso molecular:142.58Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS:ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate inhibits NAD(P)H: quinone oxidoreductase 1.Fórmula:C12H10ClNO3Pureza:99.17%Cor e Forma:SolidPeso molecular:251.67ω-Conotoxin MVIIC
CAS:Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.Fórmula:C106H178N40O32S7Pureza:98%Cor e Forma:White Lyophilised SolidPeso molecular:2749Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Fórmula:C20H25ClN2O5·C6H6O3SH2OCor e Forma:SolidPeso molecular:1224.18MCU-i11
CAS:MCU-i11 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.Fórmula:C28H28N4O5SPureza:98.3%Cor e Forma:SolidPeso molecular:532.61Ref: TM-T9960
1mg160,00€5mg359,00€10mg512,00€25mg847,00€50mg1.159,00€100mg1.568,00€1mL*10mM (DMSO)437,00€KT-362 free base
CAS:KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.Fórmula:C22H28N2O3SPureza:99.91%Cor e Forma:SoildPeso molecular:400.53MMK 1
CAS:Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.Fórmula:C75H123N19O18SPureza:98%Cor e Forma:SolidPeso molecular:1610.97Glutarimide
CAS:Compound PDK0025, with CAS No. 1121-89-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0025 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C5H7NO2Peso molecular:113.11Candidalysin
CAS:<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Fórmula:C153H266N38O38S2Cor e Forma:SolidPeso molecular:3310.11Fasudil
CAS:Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Fórmula:C14H17N3O2SPureza:99.79% - 99.84%Cor e Forma:SolidPeso molecular:291.37Lnd 796
CAS:Lnd 796 is an aminosteroid related to LND 623.Fórmula:C27H45NO7Cor e Forma:SolidPeso molecular:495.65Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Cor e Forma:Odour SolidN-Palmitoyl Glycine
CAS:Acyl amides like AEA modulate pain/inflammation. PalGly, similar to N-acyl ethanolamines, inhibits nociception and induces calcium influx in cells.Fórmula:C18H35NO3Cor e Forma:SolidPeso molecular:313.48Catharanthine
CAS:Catharanthine ((+)-3,4-Didehydrocoronaridine) suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM).Fórmula:C21H24N2O2Pureza:99.11%Cor e Forma:White PowderPeso molecular:336.43CCT129957
CAS:CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity andFórmula:C17H15N3O3Pureza:99.69%Cor e Forma:SolidPeso molecular:309.32Ref: TM-T14903
1mg47,00€5mg87,00€10mg133,00€25mg233,00€50mg349,00€100mg525,00€500mg1.111,00€1mL*10mM (DMSO)97,00€(R)-(+)-Bay-K-8644
CAS:<p>(R)-(+)-Bay-K-8644, a Ca2+ channel agonist, is a dihydropyridine agonist that induces central respiratory depression and inhibits platelet activation in cats.</p>Fórmula:C16H15F3N2O4Pureza:96.51% - 96.51%Cor e Forma:SolidPeso molecular:356.3TPC2-A1-N
CAS:TPC2-A1-N is a TPC2 small molecule agonist that can be used to detect different functions of TPC2 channels in intact cells.Fórmula:C17H9Cl2F3N2O2Pureza:99.86%Cor e Forma:SolidPeso molecular:401.17Norverapamil-d7 HCl
CAS:Norverapamil-d7 HCl (D591-d7 HCl) is a 2H-labeled Norverapamil HCl, a calcium channel blocker and P-gp inhibitor, also a coronary vasodilator.Fórmula:C26H37ClN2O4Cor e Forma:SolidPeso molecular:484.08(S)-Lercanidipine D3 hydrochloride
CAS:(S)-Lercanidipine D3 hydrochloride is a deuterium labeled Lercanidipine D3 hydrochloride. (S)-Lercanidipine hydrochloride is an agent of antihypertensive.Fórmula:C36H42ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:651.21(R)-Nicardipine
CAS:(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).Fórmula:C26H29N3O6Cor e Forma:SolidPeso molecular:479.53Almorexant hydrochloride
CAS:Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.Fórmula:C29H32ClF3N2O3Pureza:99.85%Cor e Forma:SolidPeso molecular:549.02YM-244769
CAS:YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3)Fórmula:C26H22FN3O3Pureza:95.62%Cor e Forma:SolidPeso molecular:443.47β-Cyfluthrin
CAS:β-Cyfluthrin is a type II synthetic pyrethroid compound commonly utilized as an active ingredient in agricultural insecticide products.Fórmula:C22H18Cl2FNO3Cor e Forma:SolidPeso molecular:434.29YM-244769 dihydrochloride
CAS:YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM.Fórmula:C26H24Cl2FN3O3Pureza:98%Cor e Forma:SolidPeso molecular:516.39(R)-Lercanidipine-d3 hydrochloride
CAS:(R)-lercanidipine D3 hydrochloride is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine D3 (hydrochloride) is a calcium channel blocker.Fórmula:C36H42ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:651.21MRS1845
CAS:MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).Fórmula:C21H22N2O6Pureza:99.69%Cor e Forma:SolidPeso molecular:398.41Nicardipine-d3 hydrochloride
CAS:Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.Fórmula:C26H30ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:519HSK16149
CAS:<p>HSK16149 is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit with analgesic activity.</p>Fórmula:C12H19NO2Cor e Forma:SolidPeso molecular:209.28(S)-Nicardipine
CAS:(S)-Nicardipine is the less active S enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).Fórmula:C26H29N3O6Cor e Forma:SolidPeso molecular:479.53Norverapamil-d7
CAS:Norverapamil D7 is a deuterium labeled Norverapamil . Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .Fórmula:C26H36N2O4Pureza:98%Cor e Forma:SolidPeso molecular:447.62Hexadecylphosphoserine TFA
Hexadecylphosphoserine is a type of phospholipid molecule that incorporates a long-chain alkyl group (hexadecyl) and a phosphatidylserine group, granting it high affinity for cell membranes. This compound exhibits antitumor activity by modulating [Ca++]i and related signaling pathways, making it useful for breast cancer research.Fórmula:C21H41F3NO8PCor e Forma:SolidPeso molecular:523.52Magnesium sulfate
CAS:Magnesium sulfate: anticonvulsant for eclampsia, tocolytic agent.Fórmula:MgSO4Pureza:98%Cor e Forma:SolidPeso molecular:120.37Etripamil
CAS:Etripamil is a fast-acting intranasal L-type calcium-channel blocker for Paroxysmal Supraventricular Tachycardia.Fórmula:C27H36N2O4Pureza:99.47% - 99.83%Cor e Forma:SolidPeso molecular:452.59Ref: TM-T15257
1mg55,00€2mg79,00€5mg116,00€10mg172,00€25mg311,00€50mg472,00€100mg707,00€200mg1.111,00€Dronedarone
CAS:Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.Fórmula:C31H44N2O5SPureza:98.85% - 99.99%Cor e Forma:SolidPeso molecular:556.76HA-1004 HCl
CAS:HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein.Fórmula:C12H17Cl2N5O2SCor e Forma:SolidPeso molecular:366.27JNJ-26990990
CAS:"JNJ-26990990: broad-spectrum anticonvulsant, less side effects than topiramate, potential for pain and depression treatment; Phase II in 2007."Fórmula:C9H10N2O2S2Pureza:97.37%Cor e Forma:SolidPeso molecular:242.32Ref: TM-T27673
1mg131,00€5mg286,00€10mg424,00€25mg702,00€50mg938,00€100mg1.311,00€1mL*10mM (DMSO)261,00€Efonidipine
CAS:Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.Fórmula:C34H38N3O7PPureza:98.35% - 99.47%Cor e Forma:SolidPeso molecular:631.66Bepridil hydrochloride
CAS:Bepridil hydrochloride (CERM 1978) is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channelsFórmula:C24H35ClN2OPureza:99.45% - 99.68%Cor e Forma:SolidPeso molecular:4032,5-Di-tert-butylhydroquinone
CAS:2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Fórmula:C14H22O2Pureza:97.11%Cor e Forma:PelletslargecrystalsPeso molecular:222.32DHBP dibromide
CAS:DHBP dibromide (1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBRO) is calcium release and a muscle relaxant inhibitor.Fórmula:C24H38Br2N2Pureza:99.73%Cor e Forma:Yellow To Yellow-Green Powder Or FlakesPeso molecular:514.38Propiverine hydrochloride
CAS:Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).Fórmula:C23H30ClNO3Pureza:99.93%Cor e Forma:White Crystalling PowerPeso molecular:403.94Levamlodipine hydrobromide
CAS:Levamlodipine hydrobromide is a medication used to lower blood pressure and prevent chest pain.Fórmula:C20H26BrClN2O5Cor e Forma:SolidPeso molecular:489.79GSK1016790A
CAS:GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelialFórmula:C28H32Cl2N4O6S2Pureza:97.37% - 99.38%Cor e Forma:SolidPeso molecular:655.61Ref: TM-T6848
1mg37,00€2mg48,00€5mg72,00€10mg113,00€25mg240,00€50mg364,00€100mg540,00€1mL*10mM (DMSO)97,00€(+)-Kavain
CAS:(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.Fórmula:C14H14O3Pureza:97% - ≥95%Cor e Forma:White Fine PowderPeso molecular:230.26(±)-Praeruptorin A
CAS:(±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation.Fórmula:C21H22O7Pureza:98.9% - 99.73%Cor e Forma:SolidPeso molecular:386.40NS-638
CAS:NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).Fórmula:C15H11ClF3N3Pureza:98.44%Cor e Forma:SolidPeso molecular:325.72Suvecaltamide
CAS:Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.Fórmula:C20H23F3N2O2Pureza:99.29% - 99.70%Cor e Forma:SolidPeso molecular:380.4Azumolene sodium anhydrous
CAS:Azumolene sodium, a muscle relaxant, blocks calcium release from muscles and halts SOCE linked to RyR1 except when induced by thapsigargin.Fórmula:C13H8BrN4NaO3Cor e Forma:SolidPeso molecular:371.13SR33805
CAS:<p>SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)</p>Fórmula:C32H40N2O5SPureza:99.15%Cor e Forma:SolidPeso molecular:564.74Mirogabalin besylate
CAS:Mirogabalin besylate is an oral α2δ ligand for voltage-gated calcium channels, with Kd values of 13.5-47.6 nM across species.Fórmula:C18H25NO5SCor e Forma:SolidPeso molecular:367.46Efonidipine hydrochloride monoethanolate
CAS:Efonidipine HCl monoethanolate is a calcium blocker, boosts dehydroepiandrosterone sulfate in NCI-H295R cells.Fórmula:C36H45ClN3O8PPureza:>99.99%Cor e Forma:SolidPeso molecular:714.18Ref: TM-T8401
2mgA consultar5mg52,00€10mg86,00€25mg154,00€50mg224,00€100mg313,00€1mL*10mM (DMSO)94,00€Praeruptorin E
CAS:Praeruptorin C/E relaxes arteries, reduces heart contractility, acting like calcium blockers. D/E protect mice from acid lung injury by halting PMNs and IL-6.Fórmula:C24H28O7Pureza:98.04% - 99.95%Cor e Forma:SolidPeso molecular:428.47TGR5 Receptor Agonist
CAS:TGR5 is a potent TGR5(GPCR19) agonist.Fórmula:C18H14Cl2N2O2Pureza:99.77% - ≥95%Cor e Forma:SolidPeso molecular:361.22Ibutilide Fumarate
CAS:Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.Fórmula:(C20H36N2O3S)2·C4H4O4Pureza:99.68% - 99.74%Cor e Forma:SolidPeso molecular:885.23Ginsenoside Rd
CAS:<p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>Fórmula:C48H82O18Pureza:99.13% - 99.92%Cor e Forma:SolidPeso molecular:947.15HC-056456
CAS:HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) is a CatSper channel modulator.Fórmula:C12H6N2O4S2Pureza:99.62% - 99.65%Cor e Forma:SolidPeso molecular:306.32Ref: TM-T4604
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg170,00€50mg274,00€100mg454,00€1mL*10mM (DMSO)77,00€Quadrol
CAS:Quadrol (EDTP) is an immunostimulant, accelerated wound healing.Fórmula:C14H32N2O4Pureza:99.91% - 99.92%Cor e Forma:Viscous Liquid Liquid ViscousPeso molecular:292.41
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