Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 372 produtos de "Receptor GABA"
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Broflanilide
CAS:Broflanilide metabolite desmethyl-broflanilide blocks GABA receptor in dieldrin-resistant insects, inhibiting S. litura at IC50 1.3 nM.Fórmula:C25H14BrF11N2O2Pureza:99.82%Cor e Forma:SolidPeso molecular:663.29Ref: TM-T10618
1mg52,00€2mg74,00€5mg111,00€1mL*10mM (DMSO)131,00€10mg180,00€25mg358,00€50mg588,00€100mg835,00€Afoxolaner
CAS:Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs.Fórmula:C26H17ClF9N3O3Pureza:99.1% - 99.38%Cor e Forma:SolidPeso molecular:625.87GABAA receptor agent 1
CAS:GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.Fórmula:C13H8ClN3O2Pureza:99.31%Cor e Forma:SolidPeso molecular:273.67Ref: TM-T11349
1mg35,00€5mg79,00€1mL*10mM (DMSO)86,00€10mg111,00€25mg215,00€50mg323,00€100mg469,00€200mg647,00€Bemegride
CAS:Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.Fórmula:C8H13NO2Pureza:99.89%Cor e Forma:Physical Description White Crystalline Solid Sublimes At 212°F And 200 Mm Pressure (Ntp 1992)Peso molecular:155.19Phenelzine sulfate
CAS:Phenelzine sulfate is a non-selective and irreversible inhibitor of monoamine oxidase (MAOI), and with antidepressant and anxiolytic.Fórmula:C8H14N2O4SPureza:98.38% - 99.83%Cor e Forma:SolidPeso molecular:234.27Fluxametamide
CAS:Fluxametamide, an isoxazoline insecticide, targets insect chloride channels with IC50s of 1.95 nM (GABA) and 225 nM (glutamate).Fórmula:C20H16Cl2F3N3O3Pureza:99.49%Cor e Forma:SolidPeso molecular:474.26Lotilaner
CAS:Lotilaner is a parasiticide.Fórmula:C20H14Cl3F6N3O3SPureza:99.56%Cor e Forma:SolidPeso molecular:596.76Ref: TM-T15775
1mg44,00€2mg58,00€5mg94,00€1mL*10mM (DMSO)111,00€10mg144,00€25mg335,00€50mg550,00€100mg882,00€200mg1.188,00€Isoguvacine hydrochloride
CAS:Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist.Fórmula:C6H10ClNO2Pureza:99.59%Cor e Forma:SolidPeso molecular:163.6Pentetrazol
CAS:Pentylenetetrazol is a GABA(A) receptor antagonist, that displays activity as a central nervous system and respiratory stimulant.Fórmula:C6H10N4Pureza:99.67% - 99.90%Cor e Forma:Bitter Taste Aqueous Solutions Neutral To Litmus (Ntp 1992)Peso molecular:138.17Flumazenil
CAS:Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervousFórmula:C15H14FN3O3Pureza:99.72% - 99.98%Cor e Forma:Less Crystals Colourless CrystalsPeso molecular:303.29γ-Aminobutyric acid
CAS:γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.Fórmula:C4H9NO2Pureza:99.95%Cor e Forma:White Or Almost White(According To Quality Test Specification It Can Be White Or Almost White ) Solid PowderPeso molecular:103.12Phenibut
CAS:Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).Fórmula:C10H13NO2Pureza:99.55%Cor e Forma:SolidPeso molecular:179.22Domperidone EP Impurity A
CAS:Domperidone EP Impurity A is used as pharmaceutical intermediates.Fórmula:C12H14ClN3OPureza:99.97%Cor e Forma:SolidPeso molecular:251.71Baclofen
CAS:Baclofen (Lioresal), a chlorophenyl-butanoic acid derivative, treats spasms from spinal cord injury and MS by mimicking GABA at GABA-B receptors.Fórmula:C10H12ClNO2Pureza:98% - >99.99%Cor e Forma:1992)Peso molecular:213.66GET73
CAS:GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5.Fórmula:C13H16F3NO2Pureza:99.54%Cor e Forma:SolidPeso molecular:275.27Ref: TM-T11393
5mg39,00€1mL*10mM (DMSO)44,00€10mg56,00€25mg104,00€50mg158,00€100mg230,00€200mg340,00€UK-124114
CAS:Selamectin, a derivative of ivermectin, is a macrocyclic lactone that enhances chloride channels in nematodes, inhibiting H. contortus larval growth.Fórmula:C43H63NO11Pureza:99.31%Cor e Forma:SolidPeso molecular:769.96Etifoxine hydrochloride
CAS:Etifoxine hydrochloride (HOE 36-801 hydrochloride) is an anxiolytic and anticonvulsant drug.Fórmula:C17H18Cl2N2OPureza:99.36%Cor e Forma:SolidPeso molecular:337.24FG 7142
CAS:FG 7142 (LSU-65), a benzodiazepine inverse agonist, targets α1 subunit GABAA receptors (EC50=137 nM, Ki=91 nM) and upregulates β-adrenoceptors.Fórmula:C13H11N3OPureza:98.75%Cor e Forma:SolidPeso molecular:225.25Ref: TM-T11277
2mg33,00€1mL*10mM (DMSO)39,00€5mg60,00€10mg92,00€25mg149,00€50mg213,00€100mg318,00€200mg442,00€Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Fórmula:C12H21NO8SPureza:99.79% - 99.92%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:339.36Nikethamide
CAS:Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of endFórmula:C10H14N2OPureza:99.42%Cor e Forma:Followed By A Faint Sensation Of The Warmth (Ntp 1992)Peso molecular:178.23Nefiracetam
CAS:Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.Fórmula:C14H18N2O2Pureza:97.37%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:246.3Clomethiazole
CAS:Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It has potential for treating convulsive status epilepticus.Fórmula:C6H8ClNSPureza:99.06%Cor e Forma:SolidPeso molecular:161.65L-Cycloserine
CAS:L-Cycloserine irreversibly inhibits E. coli GABA aminotransferase, raising GABA levels, an inhibitory neurotransmitter.Fórmula:C3H6N2O2Pureza:99.75% - 99.99%Cor e Forma:Crystals White PowderPeso molecular:102.09Chlormezanone
CAS:Chlormezanone (Trancopal) is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.Fórmula:C11H12ClNO3SPureza:99.86% - >99.99%Cor e Forma:Crystals SolidPeso molecular:273.743,4,5-Trimethoxycinnamic acid
CAS:3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at theFórmula:C12H14O5Pureza:98.91%Cor e Forma:SolidPeso molecular:238.24Pivagabine
CAS:Pivagabine (CXB-722), a 4-aminobutyric acid derivative, modulates GABA, CRF, and crosses the rat blood-brain barrier.Fórmula:C9H17NO3Pureza:99.87%Cor e Forma:SolidPeso molecular:187.24LAU159
CAS:LAU159 is a functionally selective positive α1β3 GABA(A) receptor modulator(EC50 : 2.2 μM).Fórmula:C17H12ClN3O2Pureza:98.7% - 99.38%Cor e Forma:SolidPeso molecular:325.75Ref: TM-T11822
1mg110,00€2mg160,00€5mg219,00€10mg395,00€25mg653,00€50mg888,00€100mg1.243,00€500mg2.493,00€NEO 376
CAS:NEO 376 (SPI-376) is a selective 5-HT1 receptor, GABA receptor and dopamine receptor modulator, showing anti-psychotic actively.Fórmula:C20H24ClN3OPureza:99.56%Cor e Forma:SolidPeso molecular:357.88Ref: TM-T12207
1mg71,00€5mg133,00€1mL*10mM (DMSO)147,00€10mg205,00€25mg353,00€50mg495,00€100mg665,00€200mg893,00€Emamectin Benzoate
CAS:Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropodsFórmula:C56H81NO15Pureza:98.68%Cor e Forma:SolidPeso molecular:1008.256Oxiracetam
CAS:Oxiracetam (ISF2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.
Fórmula:C6H10N2O3Pureza:99.67%Cor e Forma:White Crystalline PowderPeso molecular:158.16α5-GABAA receptor modulator 1
α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.Fórmula:C21H20FN3O4Cor e Forma:SolidPeso molecular:397.4α-Casozepine
CAS:α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.Fórmula:C60H94N14O16Cor e Forma:SolidPeso molecular:1267.47RuBi-GABA
CAS:Ruthenium-bipyridine-triphenylphosphine caged GABAFórmula:C42H39F6N5O2P2RuPureza:98%Cor e Forma:SolidPeso molecular:922.8DAA-1106
CAS:DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.Fórmula:C23H22FNO4Pureza:99.54%Cor e Forma:SolidPeso molecular:395.42Anticonvulsant agent 8
Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.Fórmula:C15H11N5OCor e Forma:SolidPeso molecular:277.28Nipecotic acid
CAS:Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
Fórmula:C6H11NO2Cor e Forma:Off-White To Pale Yellow-Beige PowderPeso molecular:129.16Fipronil sulfone
CAS:Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.Fórmula:C12H4Cl2F6N4O2SPureza:98%Cor e Forma:SolidPeso molecular:453.14Chrodrimanin B
CAS:Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Fórmula:C27H32O8Cor e Forma:SolidPeso molecular:484.545Imagabalin
CAS:Imagabalin is an active compound used in the study of neurological diseases.Fórmula:C9H19NO2Cor e Forma:SolidPeso molecular:173.25Lesogaberan napadisylate
CAS:Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.Fórmula:C13H17FNO5PSCor e Forma:SolidPeso molecular:349.31Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Fórmula:C12H10ClN2NaO5SPureza:99.52% - >99.99%Cor e Forma:SolidPeso molecular:352.73Azocarnil
Azocarnil is a GABAergic agonist-enhancer used in neurological system research.Cor e Forma:Odour Solid6,7-dimethylisatin
CAS:6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.Fórmula:C10H9NO2Pureza:98.98%Cor e Forma:SolidPeso molecular:175.18Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.Fórmula:C19H38ClN5O2SCor e Forma:SolidPeso molecular:436.06Nitrazolam
CAS:Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.Fórmula:C17H13N5O2Cor e Forma:SolidPeso molecular:319.32epi-Aszonalenin A
CAS:epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48CGP 35348
CAS:CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。Fórmula:C8H20NO4PPureza:≥98%Cor e Forma:SolidPeso molecular:225.22Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Cor e Forma:Odour SolidAHN-683
CAS:AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.Fórmula:C42H32FN3O7Pureza:98%Cor e Forma:SolidPeso molecular:709.72Ion Channel Targeted Library
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
Cor e Forma:Odour Solid
