Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 363 produtos para "Receptor GABA".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Nikethamide
CAS:Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of endFórmula:C10H14N2OPureza:99.42%Cor e Forma:SolidPeso molecular:178.23Baclofen
CAS:Baclofen (Lioresal), a chlorophenyl-butanoic acid derivative, treats spasms from spinal cord injury and MS by mimicking GABA at GABA-B receptors.Fórmula:C10H12ClNO2Pureza:98% - 99.94%Cor e Forma:White SolidPeso molecular:213.66Isoguvacine hydrochloride
CAS:Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist.Fórmula:C6H10ClNO2Pureza:99.59%Cor e Forma:SolidPeso molecular:163.6Bemegride
CAS:Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.Fórmula:C8H13NO2Pureza:99.89%Cor e Forma:SolidPeso molecular:155.19Etifoxine hydrochloride
CAS:Etifoxine hydrochloride (HOE 36-801 hydrochloride) is an anxiolytic and anticonvulsant drug.Fórmula:C17H18Cl2N2OPureza:99.36%Cor e Forma:SolidPeso molecular:337.24Fluxametamide
CAS:Fluxametamide, an isoxazoline insecticide, targets insect chloride channels with IC50s of 1.95 nM (GABA) and 225 nM (glutamate).Fórmula:C20H16Cl2F3N3O3Pureza:99.49%Cor e Forma:SolidPeso molecular:474.26Lotilaner
CAS:Lotilaner is a parasiticide.Fórmula:C20H14Cl3F6N3O3SPureza:99.56%Cor e Forma:SolidPeso molecular:596.76Ref: TM-T15775
1mg42,00€2mg55,00€5mg89,00€1mL*10mM (DMSO)105,00€10mg137,00€25mg318,00€50mg522,00€100mg835,00€200mg1.125,00€FG 7142
CAS:FG 7142 (LSU-65), a benzodiazepine inverse agonist, targets α1 subunit GABAA receptors (EC50=137 nM, Ki=91 nM) and upregulates β-adrenoceptors.Fórmula:C13H11N3OPureza:98.75%Cor e Forma:White SolidPeso molecular:225.25Ref: TM-T11277
2mg33,00€1mL*10mM (DMSO)39,00€5mg60,00€10mg92,00€25mg149,00€50mg213,00€100mg318,00€200mg442,00€3,4,5-Trimethoxycinnamic acid
CAS:3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at theFórmula:C12H14O5Pureza:98.91%Cor e Forma:SolidPeso molecular:238.24Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Fórmula:C12H10ClN2NaO5SPureza:99.52% - >99.99%Cor e Forma:SolidPeso molecular:352.73GET73
CAS:GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5.Fórmula:C13H16F3NO2Pureza:99.54%Cor e Forma:SolidPeso molecular:275.27Ref: TM-T11393
5mg39,00€1mL*10mM (DMSO)44,00€10mg56,00€25mg104,00€50mg158,00€100mg230,00€200mg340,00€γ-Aminobutyric acid
CAS:γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.Fórmula:C4H9NO2Pureza:99.95%Cor e Forma:White SolidPeso molecular:103.12Nefiracetam
CAS:Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.Fórmula:C14H18N2O2Pureza:97.37%Cor e Forma:SolidPeso molecular:246.3Oxiracetam
CAS:Oxiracetam (ISF2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.Fórmula:C6H10N2O3Pureza:99.67%Cor e Forma:White Crystalline PowderPeso molecular:158.16L-Cycloserine
CAS:L-Cycloserine irreversibly inhibits E. coli GABA aminotransferase, raising GABA levels, an inhibitory neurotransmitter.Fórmula:C3H6N2O2Pureza:99.92% - 99.99%Cor e Forma:White SolidPeso molecular:102.09UK-124114
CAS:Selamectin, a derivative of ivermectin, is a macrocyclic lactone that enhances chloride channels in nematodes, inhibiting H. contortus larval growth.Fórmula:C43H63NO11Pureza:99.64%Cor e Forma:White SolidPeso molecular:769.96Phenibut
CAS:Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).Fórmula:C10H13NO2Pureza:99.55%Cor e Forma:White SolidPeso molecular:179.22Chlormezanone
CAS:Chlormezanone (Trancopal) is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.Fórmula:C11H12ClNO3SPureza:99.86% - >99.99%Cor e Forma:White SolidPeso molecular:273.74Broflanilide
CAS:Broflanilide metabolite desmethyl-broflanilide blocks GABA receptor in dieldrin-resistant insects, inhibiting S. litura at IC50 1.3 nM.Fórmula:C25H14BrF11N2O2Pureza:99.82%Cor e Forma:SolidPeso molecular:663.29Ref: TM-T10618
1mg50,00€2mg71,00€5mg105,00€1mL*10mM (DMSO)124,00€10mg170,00€25mg339,00€50mg557,00€100mg792,00€Pentetrazol
CAS:Pentylenetetrazol is a GABA(A) receptor antagonist, that displays activity as a central nervous system and respiratory stimulant.Fórmula:C6H10N4Pureza:99.67% - 99.90%Cor e Forma:SolidPeso molecular:138.17NEO 376
CAS:NEO 376 (SPI-376) is a selective 5-HT1 receptor, GABA receptor and dopamine receptor modulator, showing anti-psychotic actively.Fórmula:C20H24ClN3OPureza:99.56%Cor e Forma:SolidPeso molecular:357.88Ref: TM-T12207
1mg71,00€5mg133,00€1mL*10mM (DMSO)147,00€10mg205,00€25mg353,00€50mg495,00€100mg665,00€200mg893,00€Pivagabine
CAS:Pivagabine (CXB-722), a 4-aminobutyric acid derivative, modulates GABA, CRF, and crosses the rat blood-brain barrier.Fórmula:C9H17NO3Pureza:99.87%Cor e Forma:White SolidPeso molecular:187.24Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Fórmula:C12H21NO8SPureza:99.79% - 99.92%Cor e Forma:SolidPeso molecular:339.36GABAA receptor agent 1
CAS:GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.Fórmula:C13H8ClN3O2Pureza:99.31%Cor e Forma:SolidPeso molecular:273.67Ref: TM-T11349
1mg35,00€5mg79,00€1mL*10mM (DMSO)86,00€10mg111,00€25mg215,00€50mg323,00€100mg469,00€200mg647,00€Emamectin Benzoate
CAS:Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropodsFórmula:C56H81NO15Pureza:98.68%Cor e Forma:SolidPeso molecular:1008.256Clomethiazole
CAS:Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It has potential for treating convulsive status epilepticus.Fórmula:C6H8ClNSPureza:99.06%Cor e Forma:SolidPeso molecular:161.65LAU159
CAS:LAU159 is a functionally selective positive α1β3 GABA(A) receptor modulator(EC50 : 2.2 μM).Fórmula:C17H12ClN3O2Pureza:98.7% - 99.38%Cor e Forma:Yellow SolidPeso molecular:325.75Ref: TM-T11822
1mg110,00€2mg160,00€5mg219,00€10mg395,00€25mg653,00€50mg888,00€100mg1.243,00€500mg2.493,00€Phenelzine sulfate
CAS:Phenelzine sulfate is a non-selective and irreversible inhibitor of monoamine oxidase (MAOI), and with antidepressant and anxiolytic.Fórmula:C8H14N2O4SPureza:98.38% - 99.83%Cor e Forma:SolidPeso molecular:234.27Domperidone EP Impurity A
CAS:Domperidone EP Impurity A is used as pharmaceutical intermediates.Fórmula:C12H14ClN3OPureza:99.97%Cor e Forma:White SolidPeso molecular:251.71Flumazenil
CAS:Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervousFórmula:C15H14FN3O3Pureza:99.72% - 99.98%Cor e Forma:White SolidPeso molecular:303.29Afoxolaner
CAS:Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs.Fórmula:C26H17ClF9N3O3Pureza:99.1% - 99.38%Cor e Forma:SolidPeso molecular:625.87α5-GABAA receptor modulator 1
α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.Fórmula:C21H20FN3O4Cor e Forma:SolidPeso molecular:397.4α-Casozepine
CAS:α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.Fórmula:C60H94N14O16Pureza:99.81%Cor e Forma:SolidPeso molecular:1267.47RuBi-GABA
CAS:Ruthenium-bipyridine-triphenylphosphine caged GABAFórmula:C42H39F6N5O2P2RuPureza:98%Cor e Forma:SolidPeso molecular:922.8Emamectin B1a
CAS:Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.Fórmula:C49H75NO13Cor e Forma:SolidPeso molecular:886.133DAA-1106
CAS:DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.Fórmula:C23H22FNO4Pureza:99.54%Cor e Forma:SolidPeso molecular:395.42Nipecotic acid
CAS:Nipecotic acid ,with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Nipecotic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C6H11NO2Cor e Forma:Off-White To Pale Yellow-Beige PowderPeso molecular:129.16AHN-683
CAS:AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.Fórmula:C42H32FN3O7Pureza:98%Cor e Forma:SolidPeso molecular:709.72Chrodrimanin B
CAS:Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Fórmula:C27H32O8Cor e Forma:SolidPeso molecular:484.545Anticonvulsant agent 8
Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.Fórmula:C15H11N5OCor e Forma:SolidPeso molecular:277.28(Iso)-Atagabalin HCl
CAS:(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.Fórmula:C10H20ClNO2Pureza:99.88% - >99.99%Cor e Forma:SolidPeso molecular:221.72Azocarnil
Azocarnil is a GABAergic agonist-enhancer used in neurological system research.Cor e Forma:Odour SolidLesogaberan napadisylate
CAS:Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.Fórmula:C13H17FNO5PSCor e Forma:SolidPeso molecular:349.3112,14-Dichlorodehydroabietic acid
CAS:12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.Fórmula:C20H26Cl2O2Cor e Forma:SolidPeso molecular:369.33Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.Fórmula:C19H38ClN5O2SCor e Forma:SolidPeso molecular:436.06epi-Aszonalenin A
CAS:epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Cor e Forma:Odour SolidIon Channel Targeted Library
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;Cor e Forma:Odour SolidRef: TM-L2300
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarCGP 35348
CAS:CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。Fórmula:C8H20NO4PPureza:99.92%Cor e Forma:Yellow SolidPeso molecular:225.22Fipronil sulfone
CAS:Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.Fórmula:C12H4Cl2F6N4O2SPureza:98%Cor e Forma:SolidPeso molecular:453.14
