Caseína quinase
As caseína quinases são uma família de proteínas quinases serina/treonina que regulam vários processos celulares, incluindo a reparação do DNA, os ritmos circadianos e a transdução de sinais. Essas quinases estão envolvidas na fosforilação de numerosas proteínas e estão implicadas em doenças como o câncer, distúrbios neurodegenerativos e síndromes metabólicas. Na CymitQuimica, oferecemos uma seleção de inibidores de caseína quinase para apoiar sua pesquisa em transdução de sinais, regulação do ciclo celular e desenvolvimento terapêutico.
Foram encontrados 143 produtos para "Caseína quinase".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
PF-4800567
CAS:PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.Fórmula:C17H18ClN5O2Pureza:99.74% - 99.76%Cor e Forma:White SolidPeso molecular:359.81LH846
CAS:LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); exhibits no inhibitory activity at CK2.Fórmula:C16H13ClN2OSPureza:90% - 98.26%Cor e Forma:SolidPeso molecular:316.81TBB
CAS:TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).Fórmula:C6HBr4N3Pureza:98.51% - 99.45%Cor e Forma:SolidPeso molecular:434.71NCC007
CAS:NCC007 is a novel CKIα and CKIδ dual inhibitors by structural modification of N9 and C2 position of longdaysin.Fórmula:C22H28F3N7Pureza:98.88%Cor e Forma:SolidPeso molecular:447.5Umbralisib hydrochloride
CAS:Umbralisib hydrochloride: PI3Kδ inhibitor; IC50=22.2 nM, EC50=24.3 nM; active vs CK1ε, EC50=6.0 μM.Fórmula:C31H25ClF3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:608.01SR-3029
CAS:SR-3029 is a potent and highly specific CK1δ/CK1ε inhibitor.Fórmula:C23H19F3N8OPureza:99.64%Cor e Forma:SolidPeso molecular:480.45(E/Z)-GO289
CAS:(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2.Fórmula:C17H15BrN4O2SPureza:98.1%Cor e Forma:SolidPeso molecular:419.3Ref: TM-T9356
2mg34,00€5mg52,00€1mL*10mM (DMSO)54,00€10mg86,00€25mg170,00€50mg250,00€100mg354,00€200mg482,00€AS-252424
CAS:AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.Fórmula:C14H8FNO4SPureza:99.06% - 99.09%Cor e Forma:Orange SolidPeso molecular:305.28Ref: TM-T6208
1mg37,00€2mg52,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg128,00€25mg205,00€50mg309,00€100mg447,00€500mg973,00€IWP-2
CAS:IWP-2 is a Wnt pathway inhibitor and an ATP-competitive CK1δ inhibitor. IWP-2 inhibits self-renewal of embryonic stem cells. Cost effective and quality assured.Fórmula:C22H18N4O2S3Pureza:96.1% - 99.49%Cor e Forma:White SolidPeso molecular:466.6Umbralisib
CAS:Umbralisib (TGR 1202) is a PI3Kδ inhibitor.Fórmula:C31H24F3N5O3Pureza:99.56% - 99.56%Cor e Forma:White SolidPeso molecular:571.55Ref: TM-T4976
1mg46,00€2mg62,00€5mg90,00€1mL*10mM (DMSO)114,00€10mg166,00€25mg324,00€50mg425,00€100mg623,00€DMAT
CAS:DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).Fórmula:C9H7Br4N3Pureza:99.48%Cor e Forma:White SolidPeso molecular:476.79Epiblastin A
CAS:Epiblastin A inhibits CK1, targets its isoenzymes, and converts EpiSCs to cESCs.Fórmula:C12H10ClN7Pureza:99.45%Cor e Forma:SolidPeso molecular:287.71TTP 22
CAS:TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.Fórmula:C16H14N2O2S2Pureza:97.08% - 97.78%Cor e Forma:SolidPeso molecular:330.42LY-364947
CAS:LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.Fórmula:C17H12N4Pureza:99.65% - 99.96%Cor e Forma:Yellow SolidPeso molecular:272.3Ref: TM-T2048
5mg62,00€1mL*10mM (DMSO)69,00€10mg78,00€25mg136,00€50mg241,00€100mg354,00€200mg530,00€500mg830,00€LY294002
CAS:LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Fórmula:C19H17NO3Pureza:98% - 99.96%Cor e Forma:White SolidPeso molecular:307.34CK1-IN-1
CAS:CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.Fórmula:C24H15F2N3Pureza:98.79%Cor e Forma:White SolidPeso molecular:383.39Ref: TM-T5393
1mg47,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg152,00€25mg289,00€50mg447,00€100mg670,00€D4476
CAS:D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).Fórmula:C23H18N4O3Pureza:99.7% - 99.96%Cor e Forma:SolidPeso molecular:398.41TA-01
CAS:TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.Fórmula:C20H12F3N3Pureza:99.55% - 99.94%Cor e Forma:SolidPeso molecular:351.32Ref: TM-T4645
2mg34,00€5mg50,00€1mL*10mM (DMSO)67,00€10mg80,00€25mg147,00€50mg224,00€100mg313,00€200mg439,00€Silmitasertib
CAS:Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).Fórmula:C19H12ClN3O2Pureza:98% - 99.90%Cor e Forma:SolidPeso molecular:349.77Ref: TM-T2259
1mg38,00€2mg49,00€5mg80,00€1mL*10mM (DMSO)88,00€10mg118,00€25mg197,00€50mg313,00€100mg492,00€500mg1.054,00€
