HMG-CoA Reductase
A HMG-CoA Redutase é uma enzima chave na via do mevalonato, responsável pela síntese de colesterol e outros isoprenoides. Inibidores da HMG-CoA redutase, comumente conhecidos como estatinas, são amplamente utilizados para reduzir os níveis de colesterol e o risco de doenças cardiovasculares. Estes inibidores também têm potenciais benefícios na pesquisa sobre câncer e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma variedade de inibidores da HMG-CoA redutase para apoiar sua pesquisa em metabolismo lipídico, saúde cardiovascular e desenvolvimento terapêutico.
Foram encontrados 36 produtos de "HMG-CoA Reductase"
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Atorvastatin lactone
CAS:Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.Fórmula:C33H33FN2O4Pureza:98.05% - 98.16%Cor e Forma:SolidPeso molecular:540.62Lipid Metabolism Compound Library
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
Cor e Forma:Odour SolidDim16 HCl
CAS:Dim16 HCl is a dual PCSK9 and HMG-CoA reductase inhibitor that enhances LDL uptake, supporting lipid metabolism and cardiovascular research.Fórmula:C29H39ClIN5Pureza:99.07% - 99.14%Cor e Forma:SoildPeso molecular:620.0124,25-Epoxycholesterol
CAS:24,25-Epoxycholesterol is an oxysterol agonist of the liver X receptor, known to inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) in hepatic cells. Additionally, 24,25-Epoxycholesterol plays a role in regulating cholesterol metabolism within the liver.Fórmula:C27H44O2Cor e Forma:SolidPeso molecular:400.64L 645164
CAS:L 645164 is an inhibitor of hydroxymethylglutaryl-CoA reductase.Fórmula:C22H23FO3Cor e Forma:SolidPeso molecular:354.41HMG-CoA Reductase-IN-1
HMG-CoA Reductase-IN-1 is an inhibitor of HMG-CoA reductase, demonstrating strong inhibitory activity on HMGR and affinity for OATP1B1, with pIC50 and pKmFórmula:C27H29N3O7Cor e Forma:SolidPeso molecular:507.54Ganoderenic acid K
CAS:Ganoderenic acid K, from Ganoderma lucidum, inhibits HMG-CoA reductase with an IC50 of 16.5 μM.Fórmula:C32H44O9Cor e Forma:SolidPeso molecular:572.69Rawsonol
CAS:Rawsonol is a HMG-CoA reductase inhibitor from the tropical green alga Avrainvillea rawsoni.Fórmula:C29H24Br4O7Cor e Forma:SolidPeso molecular:804.11(3S,5R)-Fluvastatin D6 sodium
CAS:(3S,5R)-Fluvastatin D6 sodium: deuterium-labeled synthetic HMG-CoA reductase inhibitor with 8 nM IC50.Fórmula:C24H25FNNaO4Pureza:98%Cor e Forma:SolidPeso molecular:439.49(Rac)-5-Keto Fluvastatin
CAS:(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) is an impurity of Fluvastatin which is an inhibitor of HMG-CoA reductase.Fórmula:C24H24FNO4Pureza:95.04%Cor e Forma:SolidPeso molecular:409.45Rosuvastatin Sodium
CAS:Rosuvastatin Sodium (ZD4522 Sodium) is a competitive HMG-CoA reductase (HMGCR) inhibitor (IC50=11 nM) with lipid-lowering and anti-atherosclerotic effects.Fórmula:C22H27FN3NaO6SCor e Forma:SolidPeso molecular:503.52Pravastatin lactone
CAS:Pravastatin lactone, a non-enzymatic stomach derivative of pravastatin, inhibits HMG-CoA reductase and stems from mevastatin.
Fórmula:C23H34O6Cor e Forma:SolidPeso molecular:406.519PPD 10558
CAS:PPD 10558, a HMG-CoA reductase inhibitor, is used potentially for treatment of primary hypercholesterolemia.Fórmula:C34H37FN2O6Cor e Forma:SolidPeso molecular:588.67Lovastatin hydroxy acid sodium (Standard)
CAS:Lovastatin hydroxy acid sodium (Standard) is the standard substance of Lovastatin hydroxy acid sodium, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Lovastatin Sodium is an HMG-CoA reductase inhibitor.Fórmula:C24H37NaO6Cor e Forma:SolidPeso molecular:444.54Atorvastatin calcium trihydrate
CAS:Atorvastatin is used to inhibits HMG-CoA reductase for lowering blood cholesterol and for prevention of events associated with cardiovascular disease.Fórmula:C66H74CaF2N4O13Cor e Forma:SolidPeso molecular:1209.39Fluvastatin potassium
CAS:Fluvastatin, a synthetic statin, lowers cholesterol and prevents heart disease.Fórmula:C24H25FKNO4Cor e Forma:SolidPeso molecular:449.567-Ketocholesterol
CAS:7-Ketocholesterol is a metabolite of CholesterolFórmula:C27H44O2Pureza:97.59% - 98.84%Cor e Forma:SolidPeso molecular:400.65Simvastatin acid ammonium
CAS:Simvastatin acid ammonium (Tenivastatin ammonium) is an HMG-CoA reductase (HMGCR) inhibitor.Fórmula:C25H43NO6Pureza:98.3%Cor e Forma:SolidPeso molecular:453.61Tenivastatin
CAS:Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor used in the study of primary hyperlipidemia.Fórmula:C25H40O6Pureza:99.56%Cor e Forma:SolidPeso molecular:436.58Pravastatin
CAS:Pravastatin (CS-514) is a competitive HMG-CoA reductase inhibitor with an IC50 of 5.6 μM for sterol synthesis, capable of lowering serum cholesterol.Fórmula:C23H36O7Pureza:99.99%Cor e Forma:White PowderPeso molecular:424.53
