
Sintase de Ácidos graxos
A sintase de ácidos graxos (FAS) é um complexo multi-enzimático responsável pela síntese de ácidos graxos de cadeia longa. A superexpressão de FAS está associada a vários distúrbios metabólicos, incluindo obesidade, diabetes e câncer. Inibir a FAS pode reduzir a biossíntese de lipídios e induzir apoptose em células cancerígenas, tornando-a um alvo promissor para a terapia contra o câncer e a pesquisa em doenças metabólicas. Na CymitQuimica, oferecemos uma variedade de inibidores de FAS para apoiar sua pesquisa em oncologia, metabolismo e desenvolvimento terapêutico.
Foram encontrados 37 produtos de "Sintase de Ácidos graxos"
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Denifanstat
CAS:Denifanstat (FASN-IN-2) is a FASN inhibitor with selective and oral activity. Denifanstat has been used in studies of steatohepatitis. Cost effective and quality assured.Fórmula:C27H29N5OPureza:98.33% - 99.35%Cor e Forma:SolidPeso molecular:439.55Ref: TM-T15271
1mg86,00€5mg177,00€10mg299,00€25mg502,00€50mg710,00€100mg1.009,00€500mg2.008,00€1mL*10mM (DMSO)205,00€PF429242 dihydrochloride
CAS:PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).
Fórmula:C25H37Cl2N3O2Pureza:99.68%Cor e Forma:SolidPeso molecular:482.49trans-C75
CAS:trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).Fórmula:C14H22O4Pureza:98.88% - 99.57%Cor e Forma:White To Off-White SolidPeso molecular:254.32Ref: TM-T10656
1mg52,00€2mg69,00€5mg96,00€10mg160,00€25mg335,00€50mg537,00€100mg753,00€1mL*10mM (DMSO)108,00€FASN-IN-3
CAS:FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).Fórmula:C24H24N4OPureza:97.41%Cor e Forma:SolidPeso molecular:384.47Ref: TM-T11557
1mg46,00€5mg94,00€10mg149,00€25mg245,00€50mg338,00€100mg480,00€200mg622,00€1mL*10mM (DMSO)103,00€CTL-12
CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 μM), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase.Fórmula:C22H21ClN4O4Cor e Forma:SolidPeso molecular:440.88Fasnall HCl
Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites.Fórmula:C19H23ClN4SPureza:99.97%Cor e Forma:SoildPeso molecular:374.93Ref: TM-T27307L
1mg90,00€5mg187,00€10mg301,00€25mg477,00€50mg665,00€100mg897,00€200mg1.198,00€1mL*10mM (DMSO)210,00€IPI-9119
CAS:IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).Fórmula:C24H19F2N5O5Pureza:99.81%Cor e Forma:SolidPeso molecular:495.43Ref: TM-T36841
1mg97,00€5mg235,00€10mg340,00€25mg543,00€50mg752,00€100mg1.017,00€200mg1.359,00€1mL*10mM (DMSO)255,00€FASN-IN-4 tosylate
CAS:FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.Fórmula:C33H35N3O7S2Cor e Forma:SolidPeso molecular:649.78Betulin ditosylate
CAS:Betulinditosylate is a derivative of Betulin, which functions as an SREBP inhibitor.
Fórmula:C44H62O6S2Cor e Forma:SolidPeso molecular:751.09FASN/SCD-IN-1
FASN/SCD-IN-1 is a Silybin derivative and an orally active inhibitor of fatty acid synthase (FASN) and stearoyl-CoA desaturase (SCD). In vitro, FASN/SCD-IN-1 demonstrates the ability to inhibit lipid deposition, reduce the transcription levels of FASN and SCD, and exhibits antioxidant, anti-inflammatory, and antifibrotic activities. It shows significant hepatoprotective effects in rat models of acute liver injury and improves pathological features such as steatosis, inflammation, and fibrosis in a mouse model of myeloproliferative-associated steatohepatitis (MASH). FASN/SCD-IN-1 can be used for MASH research.Cor e Forma:Odour SolidCTL-06
CTL-06, a Fatty Acid Synthase (FASN) inhibitor with an IC50 of 3 μM, induces apoptosis, while CTL-12 impedes cell cycle progression in the Sub-G1/S phase andFórmula:C21H21ClN4O4Cor e Forma:SolidPeso molecular:428.87ACSS2-IN-2
CAS:MTB-9655 inhibits ACSS2 with 3.8 nM IC50, useful in research of viral, metabolic, neuropsychiatric diseases, inflammation, and cancer.Fórmula:C21H19F2N3O4Pureza:99.5%Cor e Forma:SoildPeso molecular:415.39Ref: TM-T60060
1mg52,00€2mg77,00€5mg113,00€10mg177,00€25mg334,00€50mg520,00€100mg750,00€1mL*10mM (DMSO)124,00€Lipid Metabolism Compound Library
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
Cor e Forma:Odour SolidFASN Protein, Human, Recombinant (His)
FASN Protein, Human, Recombinant (His) is expressed in E.Cor e Forma:Lyophilized PowderPeso molecular:35.26 kDa (predicted)Ref: TM-TMPY-06683
5µg109,00€10µg174,00€20µg289,00€50µg576,00€100µg1.017,00€200µg1.718,00€500µg4.207,00€Anti-FASN Antibody (6U56)
Anti-FASN Antibody (6U56) is an antibody targeting FASN. Anti-FASN Antibody (6U56) can be used in ELISA, IF, FCM.Cor e Forma:Odour LiquidGSK2194069
CAS:GSK2194069: Fatty acid synthase inhibitor, β-keto reductase-specific, IC50 7.7 nM, hampers cancer cell proliferation.Fórmula:C25H24N4O3Pureza:98.759% - 99.84%Cor e Forma:SolidPeso molecular:428.48Ref: TM-T15429
2mg73,00€5mg110,00€10mg178,00€25mg339,00€50mg527,00€100mg875,00€200mg1.161,00€1mL*10mM (DMSO)120,00€BI 99179
CAS:BI 99179 is a selective and potent inhibitor of type I fatty acid synthase (FAS), a tool compound for targeting FAS for cancer research.
Fórmula:C23H25N3O3Pureza:98.73%Cor e Forma:SolidPeso molecular:391.46FASN Protein, Mouse, Recombinant (His)
FASN Protein, Mouse, Recombinant (His) is expressed in E.Pureza:≥ 95 % as determined by SDS-PAGE. - ≥ 95 % as determined by SDS-PAGE.Cor e Forma:Lyophilized PowderPeso molecular:34.23 kDa (predicted)Ref: TM-TMPY-06686
5µg109,00€10µg174,00€20µg289,00€50µg576,00€100µg1.017,00€200µg1.718,00€500µg4.207,00€FT113
CAS:FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activityFórmula:C22H20FN3O4Pureza:97.05%Cor e Forma:SolidPeso molecular:409.41Fas C-Terminal Tripeptide Acetate
Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.Fórmula:C18H33N3O8Pureza:99.12%Cor e Forma:SolidPeso molecular:419.47Ref: TM-T21724L
2mg46,00€5mg69,00€10mg96,00€25mg170,00€50mg239,00€100mg339,00€200mg465,00€1mL*10mM (DMSO)82,00€

