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Sintase de Ácidos graxos

Sintase de Ácidos graxos

A sintase de ácidos graxos (FAS) é um complexo multi-enzimático responsável pela síntese de ácidos graxos de cadeia longa. A superexpressão de FAS está associada a vários distúrbios metabólicos, incluindo obesidade, diabetes e câncer. Inibir a FAS pode reduzir a biossíntese de lipídios e induzir apoptose em células cancerígenas, tornando-a um alvo promissor para a terapia contra o câncer e a pesquisa em doenças metabólicas. Na CymitQuimica, oferecemos uma variedade de inibidores de FAS para apoiar sua pesquisa em oncologia, metabolismo e desenvolvimento terapêutico.

Foram encontrados 38 produtos de "Sintase de Ácidos graxos"

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  • Denifanstat

    CAS:
    Denifanstat (FASN-IN-2) is a FASN inhibitor with selective and oral activity. Denifanstat has been used in studies of steatohepatitis. Cost effective and quality assured.
    Fórmula:C27H29N5O
    Pureza:98.33% - 99.35%
    Cor e Forma:Solid
    Peso molecular:439.55
  • PF429242 dihydrochloride

    CAS:
    <p>PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).</p>
    Fórmula:C25H37Cl2N3O2
    Pureza:99.68%
    Cor e Forma:Solid
    Peso molecular:482.49
  • trans-C75

    CAS:
    <p>trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).</p>
    Fórmula:C14H22O4
    Pureza:98.88% - 99.57%
    Cor e Forma:White To Off-White Solid
    Peso molecular:254.32
  • FASN-IN-3

    CAS:
    <p>FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).</p>
    Fórmula:C24H24N4O
    Pureza:97.41%
    Cor e Forma:Solid
    Peso molecular:384.47
  • CTL-12


    <p>CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 μM), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase.</p>
    Fórmula:C22H21ClN4O4
    Cor e Forma:Solid
    Peso molecular:440.88
  • Fasnall HCl


    Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites.
    Fórmula:C19H23ClN4S
    Pureza:99.97%
    Cor e Forma:Soild
    Peso molecular:374.93
  • IPI-9119

    CAS:
    IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).
    Fórmula:C24H19F2N5O5
    Pureza:99.81%
    Cor e Forma:Solid
    Peso molecular:495.43
  • FASN-IN-4 tosylate

    CAS:
    FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.
    Fórmula:C33H35N3O7S2
    Cor e Forma:Solid
    Peso molecular:649.78
  • Betulin ditosylate

    CAS:
    <p>Betulinditosylate is a derivative of Betulin, which functions as an SREBP inhibitor.</p>
    Fórmula:C44H62O6S2
    Cor e Forma:Solid
    Peso molecular:751.09
  • FASN/SCD-IN-1


    FASN/SCD-IN-1 is a Silybin derivative and an orally active inhibitor of fatty acid synthase (FASN) and stearoyl-CoA desaturase (SCD). In vitro, FASN/SCD-IN-1 demonstrates the ability to inhibit lipid deposition, reduce the transcription levels of FASN and SCD, and exhibits antioxidant, anti-inflammatory, and antifibrotic activities. It shows significant hepatoprotective effects in rat models of acute liver injury and improves pathological features such as steatosis, inflammation, and fibrosis in a mouse model of myeloproliferative-associated steatohepatitis (MASH). FASN/SCD-IN-1 can be used for MASH research.
    Cor e Forma:Odour Solid
  • CTL-06


    CTL-06, a Fatty Acid Synthase (FASN) inhibitor with an IC50 of 3 μM, induces apoptosis, while CTL-12 impedes cell cycle progression in the Sub-G1/S phase and
    Fórmula:C21H21ClN4O4
    Cor e Forma:Solid
    Peso molecular:428.87
  • ACSS2-IN-2

    CAS:
    MTB-9655 inhibits ACSS2 with 3.8 nM IC50, useful in research of viral, metabolic, neuropsychiatric diseases, inflammation, and cancer.
    Fórmula:C21H19F2N3O4
    Pureza:99.5%
    Cor e Forma:Soild
    Peso molecular:415.39
  • Lipid Metabolism Compound Library


    <p>A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).</p>
    Cor e Forma:Odour Solid
  • FASN Protein, Human, Recombinant (His)


    FASN Protein, Human, Recombinant (His) is expressed in E.
    Cor e Forma:Lyophilized Powder
    Peso molecular:35.26 kDa (predicted)
  • Anti-FASN Antibody (6U56)


    Anti-FASN Antibody (6U56) is an antibody targeting FASN. Anti-FASN Antibody (6U56) can be used in ELISA, IF, FCM.
    Cor e Forma:Odour Liquid
  • GSK2194069

    CAS:
    GSK2194069: Fatty acid synthase inhibitor, β-keto reductase-specific, IC50 7.7 nM, hampers cancer cell proliferation.
    Fórmula:C25H24N4O3
    Pureza:98.759% - 99.84%
    Cor e Forma:Solid
    Peso molecular:428.48
  • BI 99179

    CAS:
    <p>BI 99179 is a selective and potent inhibitor of type I fatty acid synthase (FAS), a tool compound for targeting FAS for cancer research.</p>
    Fórmula:C23H25N3O3
    Pureza:98.73%
    Cor e Forma:Solid
    Peso molecular:391.46
  • FASN Protein, Mouse, Recombinant (His)


    <p>FASN Protein, Mouse, Recombinant (His) is expressed in E.</p>
    Pureza:≥ 95 % as determined by SDS-PAGE. - ≥ 95 % as determined by SDS-PAGE.
    Cor e Forma:Lyophilized Powder
    Peso molecular:34.23 kDa (predicted)
  • Fas C-Terminal Tripeptide Acetate


    Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.
    Fórmula:C18H33N3O8
    Pureza:99.12%
    Cor e Forma:Solid
    Peso molecular:419.47
  • Ac-CoA Synthase Inhibitor1

    CAS:
    Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2).
    Fórmula:C20H18N4O2S2
    Pureza:99.26% - 99.84%
    Cor e Forma:Solid
    Peso molecular:410.51