Sintase de Ácidos graxos
A sintase de ácidos graxos (FAS) é um complexo multi-enzimático responsável pela síntese de ácidos graxos de cadeia longa. A superexpressão de FAS está associada a vários distúrbios metabólicos, incluindo obesidade, diabetes e câncer. Inibir a FAS pode reduzir a biossíntese de lipídios e induzir apoptose em células cancerígenas, tornando-a um alvo promissor para a terapia contra o câncer e a pesquisa em doenças metabólicas. Na CymitQuimica, oferecemos uma variedade de inibidores de FAS para apoiar sua pesquisa em oncologia, metabolismo e desenvolvimento terapêutico.
Foram encontrados 40 produtos para "Sintase de Ácidos graxos".
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PF429242 dihydrochloride
CAS:PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).Fórmula:C25H37Cl2N3O2Pureza:99.68%Cor e Forma:White ViscousPeso molecular:482.49FASN-IN-3
CAS:FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).Fórmula:C24H24N4OPureza:97.41%Cor e Forma:SolidPeso molecular:384.4736Denifanstat
CAS:Denifanstat (FASN-IN-2) is a FASN inhibitor with selective and oral activity. Denifanstat has been used in studies of steatohepatitis. Cost effective and quality assured.Fórmula:C27H29N5OPureza:98.33% - 99.35%Cor e Forma:SolidPeso molecular:439.5521trans-C75
CAS:trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).Fórmula:C14H22O4Pureza:98.88% - 99.57%Cor e Forma:White To Off-White SolidPeso molecular:254.3221IPI-9119
CAS:IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).Fórmula:C24H19F2N5O5Pureza:99.81%Cor e Forma:SolidPeso molecular:495.435Lipid Metabolism Compound Library
A unique collection of xnum compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).Cor e Forma:Odour SolidFASN-IN-4 tosylate
CAS:FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.Fórmula:C33H35N3O7S2Cor e Forma:SolidPeso molecular:649.777CTL-12
CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 μM), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase.Fórmula:C22H21ClN4O4Cor e Forma:SolidPeso molecular:440.88Fasnall HCl
Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites.Fórmula:C19H23ClN4SPureza:99.97%Cor e Forma:SolidPeso molecular:374.93C75
CAS:C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).Fórmula:C14H22O4Pureza:98.84% - >99.99%Cor e Forma:White SolidPeso molecular:254.32FASN/SCD-IN-1
FASN/SCD-IN-1 is a Silybin derivative and an orally active inhibitor of fatty acid synthase (FASN) and stearoyl-CoA desaturase (SCD). In vitro, FASN/SCD-IN-1 demonstrates the ability to inhibit lipid deposition, reduce the transcription levels of FASN and SCD, and exhibits antioxidant, anti-inflammatory, and antifibrotic activities. It shows significant hepatoprotective effects in rat models of acute liver injury and improves pathological features such as steatosis, inflammation, and fibrosis in a mouse model of myeloproliferative-associated steatohepatitis (MASH). FASN/SCD-IN-1 can be used for MASH research.Cor e Forma:Odour SolidHpFabZ Inhibitor 1
CAS:HpFabZ Inhibitor 1 (compound 1) is a selective inhibitor of HpFabZ (H. pyloriFórmula:C13H9Br2N3O3Pureza:99.30%Peso molecular:415.037ACSS2-IN-2
CAS:MTB-9655 inhibits ACSS2 with 3.8 nM IC50, useful in research of viral, metabolic, neuropsychiatric diseases, inflammation, and cancer.Fórmula:C21H19F2N3O4Pureza:99.5%Cor e Forma:SoildPeso molecular:415.3901FASN Protein, Human, Recombinant (His)
FASN Protein, Human, Recombinant (His) is expressed in E.Cor e Forma:Lyophilized PowderPeso molecular:35.26 kDa (predicted)Anti-FASN Antibody (6U56)
Anti-FASN Antibody (6U56) is an antibody targeting FASN. Anti-FASN Antibody (6U56) can be used in ELISA, IF, FCM.Cor e Forma:Odour LiquidGSK2194069
CAS:GSK2194069: Fatty acid synthase inhibitor, β-keto reductase-specific, IC50 7.7 nM, hampers cancer cell proliferation.Fórmula:C25H24N4O3Pureza:98.75% - 99.84%Cor e Forma:Yellow SolidPeso molecular:428.48BI 99179
CAS:BI 99179 is a selective and potent inhibitor of type I fatty acid synthase (FAS), a tool compound for targeting FAS for cancer research.Fórmula:C23H25N3O3Pureza:98.73%Cor e Forma:SolidPeso molecular:391.4629FASN Protein, Mouse, Recombinant (His)
FASN Protein, Mouse, Recombinant (His) is expressed in E.Pureza:≥ 95 % as determined by SDS-PAGE. - ≥ 95 % as determined by SDS-PAGE.Cor e Forma:White Lyophilized PowderPeso molecular:34.23 kDa (predicted)FT113
CAS:FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activityFórmula:C22H20FN3O4Pureza:97.05%Cor e Forma:SolidPeso molecular:409.4103PF 429242
CAS:PF-429242 inhibits SREBP site 1 protease selectively (IC50: 0.175 μM); reduces cholesterol synthesis in CHO cells (IC50: 0.53 μM).Fórmula:C25H35N3O2Pureza:99.27%Cor e Forma:SolidPeso molecular:409.56
