Lipoxigenase
As lipoxigenases são uma família de enzimas que catalisam a oxigenação de ácidos graxos poli-insaturados, levando à produção de mediadores lipídicos bioativos, como os leucotrienos e as lipoxinas. Esses mediadores desempenham papéis críticos na inflamação, nas respostas imunes e no câncer. Inibidores de lipoxigenase são utilizados para estudar seu papel em doenças inflamatórias, asma e câncer. Na CymitQuimica, oferecemos uma variedade de inibidores de lipoxigenase para apoiar sua pesquisa em inflamação, oncologia e metabolismo lipídico.
Foram encontrados 124 produtos de "Lipoxigenase"
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Indirubin-3'-monoxime
CAS:<p>Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/</p>Fórmula:C16H11N3O2Pureza:99.55%Cor e Forma:Dark Red SolidPeso molecular:277.28Phenethyl ferulate
CAS:<p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>Fórmula:C18H18O4Pureza:99.88% - 99.91%Cor e Forma:SolidPeso molecular:298.33Tepoxalin
CAS:<p>Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.</p>Fórmula:C20H20ClN3O3Pureza:99.94%Cor e Forma:SolidPeso molecular:385.843-Hydroxycoumarin
CAS:<p>3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitors</p>Fórmula:C9H6O3Pureza:99.5% - 99.77%Cor e Forma:SolidPeso molecular:162.14ML355
CAS:<p>ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.</p>Fórmula:C21H19N3O4S2Pureza:98.02% - 98.2%Cor e Forma:SolidPeso molecular:441.52Psoralidin
CAS:<p>Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.</p>Fórmula:C20H16O5Pureza:98% - 99.61%Cor e Forma:SolidPeso molecular:336.34Caffeic Acid
CAS:<p>Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!</p>Fórmula:C9H8O4Pureza:98.89% - 99.3%Cor e Forma:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Peso molecular:180.16PGS-IN-1
CAS:<p>PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).</p>Fórmula:C19H26O3Pureza:99.39%Cor e Forma:SolidPeso molecular:302.414',5-Dihydroxyflavone
CAS:<p>4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).</p>Fórmula:C15H10O4Pureza:99.81%Cor e Forma:SolidPeso molecular:254.24S-(+)-Marmesin
CAS:<p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>Fórmula:C14H14O4Pureza:98.00% - ≥98%Cor e Forma:SolidPeso molecular:246.26LOX-IN-3 dihydrochloride
CAS:<p>LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).</p>Fórmula:C13H15Cl2FN2O2SPureza:99.96%Cor e Forma:SolidPeso molecular:353.242,5-Di-tert-butylhydroquinone
CAS:<p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>Fórmula:C14H22O2Pureza:97.11%Cor e Forma:PelletslargecrystalsPeso molecular:222.32ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:<p>ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.</p>Fórmula:C12H13NO3Pureza:98.9%Cor e Forma:Off-White To Light Tan Crystalline PowderPeso molecular:219.24Xanthatin
CAS:<p>Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.</p>Fórmula:C15H18O3Pureza:98.48% - 99.96%Cor e Forma:SolidPeso molecular:246.3BI-0115
CAS:<p>BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.</p>Fórmula:C15H14ClN3OPureza:99.34%Cor e Forma:SolidPeso molecular:287.74Malotilate
CAS:<p>Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.</p>Fórmula:C12H16O4S2Pureza:99.79% - 99.79%Cor e Forma:SolidPeso molecular:288.383-O-Acetyl-11-hydroxy-β-boswellic acid
CAS:<p>3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).</p>Fórmula:C32H50O5Pureza:98.24%Cor e Forma:SolidPeso molecular:514.74Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Fórmula:C23H22ClNO2Pureza:99.25%Cor e Forma:Yellowish SolidPeso molecular:379.88Phenidone
CAS:<p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>Fórmula:C9H10N2OPureza:97.24%Cor e Forma:White Solid Solid CrystallinePeso molecular:162.19Chebulagic acid
CAS:<p>Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.</p>Fórmula:C41H30O27Pureza:97.82% - 99.8%Cor e Forma:SolidPeso molecular:954.66
