Lipoxigenase
As lipoxigenases são uma família de enzimas que catalisam a oxigenação de ácidos graxos poli-insaturados, levando à produção de mediadores lipídicos bioativos, como os leucotrienos e as lipoxinas. Esses mediadores desempenham papéis críticos na inflamação, nas respostas imunes e no câncer. Inibidores de lipoxigenase são utilizados para estudar seu papel em doenças inflamatórias, asma e câncer. Na CymitQuimica, oferecemos uma variedade de inibidores de lipoxigenase para apoiar sua pesquisa em inflamação, oncologia e metabolismo lipídico.
Foram encontrados 133 produtos de "Lipoxigenase"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Phenidone
CAS:Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Fórmula:C9H10N2OPureza:97.24%Cor e Forma:White Solid Solid CrystallinePeso molecular:162.19ML351
CAS:ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).Fórmula:C15H11N3OPureza:97.67%Cor e Forma:SolidPeso molecular:249.27Ref: TM-T21902
1mg50,00€5mg105,00€10mg167,00€25mg334,00€50mg505,00€100mg713,00€1mL*10mM (DMSO)117,00€SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Fórmula:C16H12FN3SPureza:98% - 99.85%Cor e Forma:SolidPeso molecular:297.354',5-Dihydroxyflavone
CAS:4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).Fórmula:C15H10O4Pureza:99.81%Cor e Forma:SolidPeso molecular:254.24Phenethyl ferulate
CAS:Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).Fórmula:C18H18O4Pureza:99.88% - 99.91%Cor e Forma:SolidPeso molecular:298.33Ref: TM-TN2330
1mg56,00€5mg119,00€10mg192,00€25mg323,00€50mg475,00€100mg687,00€1mL*10mM (DMSO)114,00€Malotilate
CAS:Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.Fórmula:C12H16O4S2Pureza:99.79% - 99.79%Cor e Forma:SolidPeso molecular:288.382,5-Di-tert-butylhydroquinone
CAS:2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Fórmula:C14H22O2Pureza:97.11%Cor e Forma:PelletslargecrystalsPeso molecular:222.32Linoleyl alcohol
CAS:Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].Fórmula:C18H34OPureza:98.12%Cor e Forma:SolidPeso molecular:266.46Psoralidin
CAS:Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.Fórmula:C20H16O5Pureza:98% - 99.61%Cor e Forma:SolidPeso molecular:336.34Ref: TM-T3399
2mg34,00€5mg50,00€10mg81,00€25mg152,00€50mg230,00€100mg340,00€200mg497,00€1mL*10mM (DMSO)55,00€Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Fórmula:C16H11N3O2Pureza:99.55%Cor e Forma:Dark Red SolidPeso molecular:277.28β-Boswellic acid
CAS:β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemicFórmula:C30H48O3Pureza:99.2% - 99.91%Cor e Forma:Off-White SolidPeso molecular:456.70Ref: TM-TN1097
1mg58,00€5mg137,00€10mg212,00€25mg363,00€50mg527,00€100mg747,00€1mL*10mM (DMSO)161,00€PGS-IN-1
CAS:PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).Fórmula:C19H26O3Pureza:99.39%Cor e Forma:SolidPeso molecular:302.41Ref: TM-T10098
1mg49,00€5mg92,00€10mg167,00€25mg349,00€50mg512,00€100mg730,00€200mg982,00€1mL*10mM (DMSO)104,00€S-(+)-Marmesin
CAS:S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Fórmula:C14H14O4Pureza:98.00% - ≥98%Cor e Forma:SolidPeso molecular:246.26Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Fórmula:C15H18O3Pureza:98.48% - 99.96%Cor e Forma:SolidPeso molecular:246.3BI-0115
CAS:BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.Fórmula:C15H14ClN3OPureza:99.34%Cor e Forma:SolidPeso molecular:287.74Pectolinarigenin
CAS:Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.
Fórmula:C17H14O6Pureza:98.67% - 99.88%Cor e Forma:SolidPeso molecular:314.29Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Fórmula:C23H22ClNO2Pureza:99.25%Cor e Forma:Yellowish SolidPeso molecular:379.88Ref: TM-T6568
5mg44,00€10mg66,00€25mg119,00€50mg177,00€100mg264,00€200mg394,00€500mg623,00€1mL*10mM (DMSO)48,00€4-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Fórmula:C16H19N5SPureza:97.18%Cor e Forma:SolidPeso molecular:313.42Ref: TM-T8794
2mg34,00€5mg52,00€10mg86,00€25mg156,00€50mg245,00€100mg403,00€200mg568,00€1mL*10mM (DMSO)58,00€ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.Fórmula:C12H13NO3Pureza:98.9%Cor e Forma:Off-White To Light Tan Crystalline PowderPeso molecular:219.24LOX-IN-3 dihydrochloride
CAS:LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).Fórmula:C13H15Cl2FN2O2SPureza:99.96%Cor e Forma:SolidPeso molecular:353.24Ref: TM-T39986
1mg57,00€5mg120,00€10mg188,00€25mg354,00€50mg588,00€100mg938,00€200mg1.320,00€1mL*10mM (DMSO)127,00€
