Lipoxigenase
As lipoxigenases são uma família de enzimas que catalisam a oxigenação de ácidos graxos poli-insaturados, levando à produção de mediadores lipídicos bioativos, como os leucotrienos e as lipoxinas. Esses mediadores desempenham papéis críticos na inflamação, nas respostas imunes e no câncer. Inibidores de lipoxigenase são utilizados para estudar seu papel em doenças inflamatórias, asma e câncer. Na CymitQuimica, oferecemos uma variedade de inibidores de lipoxigenase para apoiar sua pesquisa em inflamação, oncologia e metabolismo lipídico.
Foram encontrados 134 produtos para "Lipoxigenase".
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Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Fórmula:C16H11N3O2Pureza:99.55%Cor e Forma:Red SolidPeso molecular:277.28Tepoxalin
CAS:Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.Fórmula:C20H20ClN3O3Pureza:99.94%Cor e Forma:SolidPeso molecular:385.84Ref: TM-T7724
1mg52,00€5mg113,00€1mL*10mM (DMSO)126,00€10mg166,00€25mg371,00€50mg557,00€100mg792,00€200mg1.071,00€BI-0115
CAS:BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.Fórmula:C15H14ClN3OPureza:99.34%Cor e Forma:Yellow SolidPeso molecular:287.74Malotilate
CAS:Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.Fórmula:C12H16O4S2Pureza:99.79% - 99.80%Cor e Forma:White SolidPeso molecular:288.383-Hydroxycoumarin
CAS:3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitorsFórmula:C9H6O3Pureza:99.5% - 99.77%Cor e Forma:SolidPeso molecular:162.14Psoralidin
CAS:Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.Fórmula:C20H16O5Pureza:98% - 99.61%Cor e Forma:SolidPeso molecular:336.34Ref: TM-T3399
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg81,00€25mg152,00€50mg230,00€100mg340,00€200mg497,00€Caffeic Acid
CAS:Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!Fórmula:C9H8O4Pureza:98.96% - 99.35%Cor e Forma:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Peso molecular:180.16PGS-IN-1
CAS:PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).Fórmula:C19H26O3Pureza:99.39%Cor e Forma:SolidPeso molecular:302.414',5-Dihydroxyflavone
CAS:4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).Fórmula:C15H10O4Pureza:99.81%Cor e Forma:SolidPeso molecular:254.24S-(+)-Marmesin
CAS:S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Fórmula:C14H14O4Pureza:98.00% - ≥98%Cor e Forma:SolidPeso molecular:246.26LOX-IN-3 dihydrochloride
CAS:LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).Fórmula:C13H15Cl2FN2O2SPureza:99.95% - 99.96%Cor e Forma:White SolidPeso molecular:353.24Ref: TM-T39986
1mg54,00€5mg114,00€1mL*10mM (DMSO)120,00€10mg178,00€25mg334,00€50mg557,00€100mg888,00€200mg1.251,00€2,5-Di-tert-butylhydroquinone
CAS:2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Fórmula:C14H22O2Pureza:97.11%Cor e Forma:White SolidPeso molecular:222.32ML355
CAS:ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.Fórmula:C21H19N3O4S2Pureza:97.17% - 98.02%Cor e Forma:SolidPeso molecular:441.52Ref: TM-T4347
1mg43,00€5mg92,00€1mL*10mM (DMSO)96,00€10mg152,00€25mg281,00€50mg462,00€100mg708,00€200mg964,00€Phenethyl ferulate
CAS:Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).Fórmula:C18H18O4Pureza:99.88% - 99.91%Cor e Forma:White SolidPeso molecular:298.33Ref: TM-TN2330
1mg56,00€1mL*10mM (DMSO)114,00€5mg119,00€10mg192,00€25mg323,00€50mg475,00€100mg687,00€3-O-Acetyl-11-hydroxy-β-boswellic acid
CAS:3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).Fórmula:C32H50O5Pureza:98.24%Cor e Forma:SolidPeso molecular:514.74SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Fórmula:C16H12FN3SPureza:98% - 99.85%Cor e Forma:SolidPeso molecular:297.35Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Fórmula:C15H18O3Pureza:98.48% - 99.96%Cor e Forma:White SolidPeso molecular:246.3Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Fórmula:C18H22O4Pureza:97.82% - 99.91%Cor e Forma:Brown SolidPeso molecular:302.36Phenidone
CAS:Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Fórmula:C9H10N2OPureza:97.24%Cor e Forma:White Solid Solid CrystallinePeso molecular:162.19Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Fórmula:C23H22ClNO2Pureza:99.25%Cor e Forma:White SolidPeso molecular:379.88Ref: TM-T6568
5mg44,00€1mL*10mM (DMSO)48,00€10mg66,00€25mg119,00€50mg177,00€100mg264,00€200mg394,00€500mg623,00€
