Lipoxigenase
As lipoxigenases são uma família de enzimas que catalisam a oxigenação de ácidos graxos poli-insaturados, levando à produção de mediadores lipídicos bioativos, como os leucotrienos e as lipoxinas. Esses mediadores desempenham papéis críticos na inflamação, nas respostas imunes e no câncer. Inibidores de lipoxigenase são utilizados para estudar seu papel em doenças inflamatórias, asma e câncer. Na CymitQuimica, oferecemos uma variedade de inibidores de lipoxigenase para apoiar sua pesquisa em inflamação, oncologia e metabolismo lipídico.
Foram encontrados 133 produtos de "Lipoxigenase"
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FPL 62064
CAS:FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandinFórmula:C16H15N3OPureza:98.79%Cor e Forma:SolidPeso molecular:265.31Ref: TM-T8356
2mg35,00€5mg52,00€10mg86,00€25mg136,00€50mg198,00€100mg298,00€200mg414,00€1mL*10mM (DMSO)73,00€ML351
CAS:ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).Fórmula:C15H11N3OPureza:97.67%Cor e Forma:SolidPeso molecular:249.27Ref: TM-T21902
1mg50,00€5mg105,00€10mg167,00€25mg334,00€50mg505,00€100mg713,00€1mL*10mM (DMSO)117,00€Linoleyl alcohol
CAS:Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].Fórmula:C18H34OPureza:98.12%Cor e Forma:SolidPeso molecular:266.463-Hydroxycoumarin
CAS:3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitorsFórmula:C9H6O3Pureza:99.5% - 99.77%Cor e Forma:SolidPeso molecular:162.1411-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Fórmula:C30H46O4Pureza:99.68%Cor e Forma:SolidPeso molecular:470.68Ref: TM-TN1182
1mg57,00€5mg130,00€10mg200,00€25mg338,00€50mg497,00€100mg710,00€1mL*10mM (DMSO)133,00€Terameprocol
CAS:Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.Fórmula:C22H30O4Pureza:99.38%Cor e Forma:SolidPeso molecular:358.47Wedelolactone
CAS:Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Fórmula:C16H10O7Pureza:98.07% - 99.87%Cor e Forma:SolidPeso molecular:314.25Ref: TM-T3384
1mg34,00€5mg71,00€10mg109,00€25mg175,00€50mg314,00€100mg414,00€500mg954,00€1mL*10mM (DMSO)50,00€CAY10698
CAS:CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).Fórmula:C17H17N3O4S2Pureza:98.97%Cor e Forma:SolidPeso molecular:391.46Ref: TM-T8950
2mg38,00€5mg52,00€10mg88,00€25mg161,00€50mg243,00€100mg355,00€200mg502,00€1mL*10mM (DMSO)62,00€U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Fórmula:C29H40N2O3Pureza:97.50%Cor e Forma:Solid Off-WhitePeso molecular:464.64a-Boswellic Acid
CAS:Produto ControladoApplications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.
References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);Fórmula:C30H48O3Cor e Forma:NeatPeso molecular:456.74-(2-Methylpropyl)benzenemethanol
CAS:Produto ControladoFórmula:C11H16OCor e Forma:NeatPeso molecular:164.24MLS000536924
CAS:MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.Fórmula:C16H15N3SCor e Forma:SolidPeso molecular:281.38tHGA
CAS:tHGA is a potent inhibitor of lipoxygenase.Fórmula:C18H24O4Pureza:98%Cor e Forma:SolidPeso molecular:304.38L 652343
CAS:L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.Fórmula:C22H14F3NO2S2Cor e Forma:SolidPeso molecular:445.48AHR-5333
CAS:AHR-5333 an antiallergy agent.Fórmula:C30H33F2NO4Pureza:98%Cor e Forma:SolidPeso molecular:509.58PF-4191834
CAS:PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.Fórmula:C22H23N3O2SPureza:99.83% - 99.98%Cor e Forma:SolidPeso molecular:393.5Ref: TM-T16503
5mg52,00€10mg84,00€25mg155,00€50mg259,00€100mg375,00€500mg815,00€1mL*10mM (DMSO)58,00€Texasin
CAS:Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase.Fórmula:C16H12O5Pureza:98%Cor e Forma:SolidPeso molecular:284.26L-651392
CAS:L-651392 is an inhibitor of leukotriene.Fórmula:C14H10BrNO3SCor e Forma:SolidPeso molecular:352.2SB 210661
CAS:SB 210661 is a potent and selective 5-lipoxygenase inhibitor.Fórmula:C16H14F2N2O4Pureza:98%Cor e Forma:SolidPeso molecular:336.29Enazadrem
CAS:Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.
Fórmula:C18H25N3OPureza:98%Cor e Forma:SolidPeso molecular:299.41
