Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(2.949 produtos)
- Antibiótico(918 produtos)
- Antifecção(23 produtos)
- DHFR(32 produtos)
- Síntese de DNA/RNA(706 produtos)
- HBV(176 produtos)
- HIV Protease(447 produtos)
- HSV(91 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
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Foram encontrados 5832 produtos de "Microbiologia/Virologia"
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Furametpyr
CAS:<p>Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.</p>Fórmula:C17H20ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:333.81Benzohydroxamic acid
CAS:<p>Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.</p>Fórmula:C7H7NO2Cor e Forma:SolidPeso molecular:137.136SARS-CoV-2 nsp14-IN-2
<p>SARS-CoV-2 nsp14-IN-2: Strong Nsp14 methyltransferase inhibitor (IC50: 0.09 μM), potential for COVID-19 research.</p>Fórmula:C21H21N5O5SCor e Forma:SolidPeso molecular:455.49Glutamate-5-kinase-IN-2
<p>Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.</p>Fórmula:C17H10ClFN2Cor e Forma:SolidPeso molecular:296.73NSC 641396
CAS:<p>NSC 641396 is a ribonucleotide reductase (RNR) inhibitor with an IC50 value of 1.2 μM. Additionally, it acts as an inhibitor of protein arginine N-methyltransferase 9 (PRMT9) and exhibits antitumor properties.</p>Fórmula:C18H13NO3Cor e Forma:SolidPeso molecular:291.301Enzyme-IN-3 disodium
CAS:<p>Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.</p>Fórmula:C20H13N3Na2O8S2Cor e Forma:SolidPeso molecular:533.442MraY-IN-3
<p>MraY-IN-3 (12a) is a potent inhibitor of the bacterial translocase MraY (IC50: 140 μM). 46 μg/ml).</p>Fórmula:C35H45N3O5Cor e Forma:SolidPeso molecular:587.75HBV-IN-19 TFA
CAS:<p>HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.</p>Fórmula:C26H31F3N2O8Cor e Forma:SolidPeso molecular:556.53Imidocarb dihydrochloride monohydrate
<p>Imidocarb dihydrochloride monohydrate is an effective antiprotozoal agent against the parasite B. bovis (IC50: 87 μg/ml).</p>Fórmula:C19H24Cl2N6O2Cor e Forma:SolidPeso molecular:439.34Antibacterial agent 188
CAS:<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Fórmula:C12H10N4SCor e Forma:SolidPeso molecular:242.3RdRP-IN-4
<p>RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.</p>Fórmula:C17H17Br2N3O2Cor e Forma:SolidPeso molecular:455.142-CEES
CAS:<p>2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.</p>Fórmula:C4H9ClSCor e Forma:SolidPeso molecular:124.632MBX-1162
CAS:<p>MBX-1162, a bis-indole compound, has demonstrated unique substrate specificity related to MepA and MepR in studies investigating its resistance mechanisms in Staphylococcus aureus. It has not shown cross-resistance with related compounds.</p>Fórmula:C30H28N6Cor e Forma:SolidPeso molecular:472.58Antimicrobial agent-29
CAS:<p>Antimicrobial Agent-29 (Compound C35) influences the interaction between human hemoglobin and the Staphylococcus aureus IsdB hemophore. This compound facilitates the identification of IsdB:Hb PPI inhibitors [1].</p>Fórmula:C19H14N4O4SCor e Forma:SolidPeso molecular:394.4BAR-072
CAS:<p>BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.</p>Fórmula:C18H13N3O6Cor e Forma:SolidPeso molecular:367.312Artefenomel
CAS:<p>Artefenomel (OZ439) is an orally active anti-malarial ozone analog with antiviral activity for the study of SARS-CoV-2 infections and malaria infections.</p>Fórmula:C28H39NO5Cor e Forma:SolidPeso molecular:469.61RAD51-IN-6
CAS:<p>RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)</p>Fórmula:C27H40N3O5PSCor e Forma:SolidPeso molecular:549.66Antibacterial agent 118
<p>Antibacterial agent 118, potent against various mycobacteria, has MIC values ranging from 10.2 to 163.0 μM. Useful in TB research.</p>Fórmula:C19H21N5O2SCor e Forma:SolidPeso molecular:383.47Neuraminidase-IN-18
CAS:<p>Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].</p>Fórmula:C22H18FN3O3SCor e Forma:SolidPeso molecular:423.46MPro N3
CAS:<p>Mpro inhibitor blocks MHV-A29, HCoV-229E, FOPV (IC50: 2.7–8.8 μM), and SARS-CoV-2 (IC50: 16.8 μM) in plaque assays.</p>Fórmula:C35H48N6O8Cor e Forma:SolidPeso molecular:680.79Emtricitabine triphosphate
CAS:<p>Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.</p>Fórmula:C8H13FN3O12P3SCor e Forma:SolidPeso molecular:487.19LpxA-IN-1
CAS:<p>LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosa</p>Fórmula:C21H11D7F3N5O3Cor e Forma:SolidPeso molecular:452.44TLR8 agonist 4
<p>TLR8 agonist 4 inhibits wild-type and lamivudine/entecavir-resistant HBV; IC50: 0.15 μM and 0.10 μM.</p>Fórmula:C28H27N5O5SCor e Forma:SolidPeso molecular:545.61N-Cbz-L-Cysteine
CAS:<p>N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].</p>Fórmula:C11H13NO4SCor e Forma:SolidPeso molecular:255.29PRRSV-IN-1
CAS:<p>PRRSV-IN-1 (Compound 4s) acts as an inhibitor of the nsp4 protease of PRRSV. It has an EC50 value of 0.45 μM against PRRSV, binds to the nsp4 protease with a Kd of 29.24 pM, and exhibits an IC50 value of 80.36 pM for nsp4 protease inhibition. PRRSV-IN-1 is applicable in antiviral infection research.</p>Fórmula:C19H18BrNO3Cor e Forma:SolidPeso molecular:388.255Antitubercular agent-16
<p>Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.</p>Fórmula:C21H27N3SCor e Forma:SolidPeso molecular:353.525-Methylcytosine hydrochloride
CAS:<p>5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.</p>Fórmula:C5H8ClN3OCor e Forma:SolidPeso molecular:161.59WRN inhibitor 7
CAS:<p>WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].</p>Fórmula:C27H23N3O6Cor e Forma:SolidPeso molecular:485.49FGI-106
CAS:<p>FGI-106 combats Ebola, Rift Valley, Dengue Fever, HCV, and HIV-1; EC50s range from 100-900 nM.</p>Fórmula:C28H38N6Pureza:98%Cor e Forma:SolidPeso molecular:458.64PptT-IN-1
<p>PptT-IN-1, a potent PptT inhibitor (IC50: 2.8 μM), shows promise for tuberculosis research.</p>Fórmula:C18H29N5O2Cor e Forma:SolidPeso molecular:347.46PAV-104
CAS:<p>PAV-104 inhibits the replication of SARS-CoV-2 at a MOI of 0.01. It interacts with the SARS-CoV-2 nucleocapsid (N) and disrupts its oligomerization, thereby preventing particle assembly.</p>Fórmula:C29H35N5O6SCor e Forma:SolidPeso molecular:581.68Antibacterial agent 169
CAS:<p>Antibacterial agent 169 (Compound 28), a pyrrolamide-type GyrB/ParE inhibitor, exhibits antibacterial properties by inhibiting Gyrase and Topo IV in Staphylococcus aureus. It has IC 50 values of 49 nmol/L and 1.513 μmol/L, respectively [1].</p>Fórmula:C19H25Cl2N5O3Cor e Forma:SolidPeso molecular:442.34Fenbenicillin potassium
CAS:<p>Fenbenicillin (Phenbenicillin) potassium is a semi-synthetic penicillin with antibacterial spectrum activity.</p>Fórmula:C22H22KN2O5SCor e Forma:SolidPeso molecular:465.584Antibacterial agent 204
CAS:<p>Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].</p>Fórmula:C14H18N2Cor e Forma:SolidPeso molecular:214.31Menoctone
CAS:<p>Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.</p>Fórmula:C24H32O3Cor e Forma:SolidPeso molecular:368.51Metallo-β-lactamase-IN-13
CAS:<p>Metallo-β-lactamase-IN-13 (Compound 13i) serves as a pan Metallo-β-Lactamase inhibitor with extended activity against Gram-negative (GN) bacteria expressing metallo-β-lactamases. It exhibits antibacterial properties effective against P. aeruginosa [1].</p>Fórmula:C15H10F3N7O2S2Cor e Forma:SolidPeso molecular:441.41MA220607
CAS:<p>MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].</p>Fórmula:C34H38INCor e Forma:SolidPeso molecular:587.58WRN inhibitor 13
CAS:<p>WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.</p>Fórmula:C16H20N2O5SCor e Forma:SolidPeso molecular:352.405Benzisothiazolone
CAS:<p>Benzisothiazolone is an isothiazolinone fungicide that demonstrates growth inhibitory activity against Escherichia coli ATCC 8739 and yeast NCYC 1354. It is utilized in studies investigating growth inhibition models.</p>Fórmula:C7H5NOSCor e Forma:SolidPeso molecular:151.19HT1171
CAS:<p>HT1171 is a potent and selective inhibitor of the Mycobacterium tuberculosis proteasome. It exhibits strong antitubercular activity against Mycobacterium tuberculosis H37Rv, with a MIC90 of 2 μg/mL and MIC of 4 μg/mL. At a concentration of 100 μM, HT1171 shows an inhibition rate of 53.8% against normal human liver cells (L02). HT1171 is applicable in antituberculosis drug research.</p>Fórmula:C7H4N2O4S2Cor e Forma:SolidPeso molecular:244.248BM635 hydrochloride
<p>BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.</p>Fórmula:C25H30ClFN2OCor e Forma:SolidPeso molecular:428.97FtsZ-IN-13
CAS:<p>FtsZ-IN-13 (Compound C11) functions as an inhibitor of the temperature-sensitive mutant Z (FtsZ), exhibiting IC50 values of 47.97 μM for FtsZSa and 34 μM for FtsZPa. It demonstrates notable antibacterial activity against Staphylococcus aureus (with a minimum inhibitory concentration of 2 μg/mL), cystic fibrosis Staphylococcus aureus clinical isolates, and methicillin-resistant Staphylococcus aureus (MRSA). FtsZ-IN-13 is applicable in research on antibiotic resistance.</p>Fórmula:C18H14N2O4S2Cor e Forma:SolidPeso molecular:386.445SARS-CoV-2-IN-24
<p>SARS-CoV-2-IN-24 blocks PLpro, altering its shape and stopping virus replication—useful for SARS-CoV-2 research.</p>Fórmula:C27H30N4O5Cor e Forma:SolidPeso molecular:490.552'-Amino-2'-deoxyadenosine
CAS:<p>2'-Amino-2'-deoxyadenosine (9-(2-Amino-2-deoxypentofuranosyl)-9H-purin-6-amine) is a nucleoside antibiotic that effectively inhibits various Mycoplasma strains.</p>Fórmula:C10H14N6O3Peso molecular:266.26DNA polymerase-IN-6
CAS:<p>DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, with EC50 values of 0.33 µM for HCMV, 1.9 µM for HSV-1, 0.76 µM for HSV-2, and 0.066 µM for EBV.</p>Fórmula:C26H28ClFN8O4Cor e Forma:SolidPeso molecular:571.003SMCypI C31
<p>SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).</p>Fórmula:C27H30N4O2SCor e Forma:SolidPeso molecular:474.62CTSL/CAPN1-IN-2
CAS:<p>CTSL/CAPN1-IN-2 (Compound 14b) serves as an orally active inhibitor targeting both CTSL and CAPN1, manifesting IC50 values of 6.88 nM for CTSL and 347.6 nM for CAPN1 respectively. This compound not only displays anti-inflammatory attributes but also features favorable pharmacokinetic properties. Moreover, CTSL/CAPN1-IN-2 shows extensive antiviral effects against coronaviruses by inhibiting viral entry [1].</p>Fórmula:C34H40N4O6Cor e Forma:SolidPeso molecular:600.7Isazofos
CAS:<p>Isazofos is a broad-spectrum organophosphate insecticide and nematicide effective in controlling a variety of lawn pests, such as nematodes (Radopholus similis). It also demonstrates efficacy in managing rice gall midge.</p>Fórmula:C9H17ClN3O3PSCor e Forma:SolidPeso molecular:313.74Anti-MRSA agent 19
CAS:<p>Anti-MRSA agent 19 (Compound 1) is an antibiotic that exhibits activity against Staphylococcus aureus. It is active against 40 clinical isolates from the CDC, representing diverse bacterial species with various resistance factors, including resistance to vancomycin, aminoglycoside/tetracycline, and oxazolidinone (median MIC=4 μg/mL).</p>Fórmula:C15H10Cl3NO4Cor e Forma:SolidPeso molecular:374.6RdRP-IN-5
CAS:<p>RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1].</p>Fórmula:C23H21N3O5Pureza:98%Cor e Forma:SolidPeso molecular:419.43AV-5080
CAS:<p>AV-5080 is an orally active neuraminidase (neuraminidase) inhibitor that is utilized in the research of both Type A and Type B influenza viruses.</p>Fórmula:C15H25FN4O4Cor e Forma:SolidPeso molecular:344.38BioA-IN-1
CAS:<p>BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.</p>Fórmula:C18H17NO3SCor e Forma:SolidPeso molecular:327.397LpxC-IN-10
CAS:<p>LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.</p>Fórmula:C30H31N5O3Cor e Forma:SolidPeso molecular:509.6ONO-5334
CAS:<p>ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).</p>Fórmula:C21H34N4O4SPureza:98.22% - 99.60%Cor e Forma:SolidPeso molecular:438.58SARS-CoV-2-IN-102
CAS:<p>SARS-CoV-2-IN-102 (example 58) is an inhibitor of the SARS-CoV papain-like protease (SARS-CoVPLpro), demonstrating an IC50 of less than 100 nM.</p>Fórmula:C29H34F2N6O2Cor e Forma:SolidPeso molecular:536.62Antifungal agent 113
CAS:<p>Antifungalagent 113 (compound 9a) serves as an effective antifungal and antibacterial agent. It exhibits strong inhibitory activity against both S. aureus and methicillin-resistant S. aureus.</p>Fórmula:C23H20O5Cor e Forma:SolidPeso molecular:376.40N-Nitrosonornicotine
CAS:<p>N-Nitrosonornicotine, a tobacco-specific nitrosamine, exhibits carcinogenic and mutagenic properties, and is capable of inducing micronuclei in C3A cells. Additionally, N-Nitrosonornicotine can form DNA adducts.</p>Fórmula:C9H11N3OCor e Forma:SolidPeso molecular:177.2GR 122222X
CAS:<p>GR 122222X is an inhibitor of topoisomerase II.</p>Fórmula:C26H35N5O11SPureza:98%Cor e Forma:SolidPeso molecular:625.65SARS-CoV-2-IN-106
CAS:<p>SARS-CoV-2-IN-106 (compound 19) is a SARS-CoV-2 papain-like protease inhibitor, displaying IC50 values of 0.44 μM for papain-like proteases and 0.18 μM for viral replication.</p>Fórmula:C31H38FN5O2Cor e Forma:SolidPeso molecular:531.66iPAF1C
CAS:<p>iPAF1C is a powerful inhibitor of the polymerase-associated factor 1 complex (PAF1C) and exhibits anti-HIV activity [1].</p>Fórmula:C27H26BrFN4OCor e Forma:SolidPeso molecular:521.42Antibacterial agent 112
<p>Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.</p>Fórmula:C35H23N5O5Cor e Forma:SolidPeso molecular:593.59BRN3OMe
CAS:<p>BRN3OMe is an effective inhibitor of HIV-1 reverse transcriptase (HIV-1 reverse transcriptase), showing potential for antiviral drug research.</p>Fórmula:C7H13N3O4Cor e Forma:SolidPeso molecular:203.196Altersolanol A
CAS:<p>Altersolanol A (Stemphylin; NSC 173943) demonstrates effective antimicrobial properties, inhibiting the growth of Bacillus subtilis and Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) ranging from 25-100 μg/mL. Additionally, it shows no phytotoxic effects on Taxus at a concentration of 4 μg/μL.</p>Fórmula:C16H16O8Cor e Forma:SolidPeso molecular:336.29HRSV/HMPV-IN-1
CAS:<p>HRSV/HMPV-IN-1 (compound 3) is an inhibitor targeting HRSV/HMPV, exhibiting EC50 values of < 0.2 μM against human RSV-A and < 0.5 μM for human MPV A2 TN/94-49. This compound is utilized in the study of bronchiolitis and pneumonia.</p>Fórmula:C34H31ClF2N4O5SCor e Forma:SolidPeso molecular:681.15L 702007
CAS:<p>L 702007 is an inhibitor of HIV-1 reverse transcriptase.</p>Fórmula:C18H25N3O2Pureza:98%Cor e Forma:SolidPeso molecular:315.41D-G23
CAS:<p>D-G23 is a selective RAD52 inhibitor. It disrupts RAD52-mediated DNA repair pathways and suppresses the growth of cancer cells deficient in BRCA1 and BRCA2. D-G23 shows promise for research into homologous recombination-related cancers caused by BRCA1/2 mutations, such as hereditary breast and ovarian cancers.</p>Fórmula:C19H22N4O3Cor e Forma:SolidPeso molecular:354.403MED6-189
CAS:<p>MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.</p>Fórmula:C17H26N2OCor e Forma:SolidPeso molecular:274.40Carbonic anhydrase inhibitor 28
<p>Carbonic anhydrase inhibitor28 (Compound 11) serves as an inhibitor for the Pseudomonas aeruginosa carbonic anhydrase. It exhibits antibacterial activity, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 0.5 and 1 μg/mL, respectively, against P. aeruginosa. Carbonic anhydrase inhibitor28 is utilized in research focused on anti-infection applications.</p>Fórmula:C24H24FN5O7SCor e Forma:SolidPeso molecular:545.54NNRT-IN-5
CAS:<p>NNRT-IN-5 (compound 10d) is an orally available non-nucleoside reverse transcriptase (Reverse Transcriptase) inhibitor.</p>Fórmula:C27H22N8Cor e Forma:SolidPeso molecular:458.52CB 30900
CAS:<p>CB30900 is a novel and effective thymidylate synthase inhibitor.</p>Fórmula:C31H32FN5O9Cor e Forma:SolidPeso molecular:637.61Antibacterial agent 261
CAS:<p>Antibacterialagent 261 (compound 43) is a potent inhibitor of the peptide deformylase (PDF) enzyme, demonstrating IC50 values of 2.5 nM against Staphylococcus aureus (S. aureus) and 10.6 nM against Escherichia coli (E. coli).</p>Fórmula:C18H24N4O3S2Cor e Forma:SolidPeso molecular:408.538Antitubercular agent-11
<p>Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].</p>Fórmula:C16H15N3O4Cor e Forma:SolidPeso molecular:313.31Antifungal agent 13
CAS:<p>Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.</p>Fórmula:C21H16ClF3N4OCor e Forma:SolidPeso molecular:432.83HIV-IN-3
<p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>Fórmula:C21H32ClN7O3Cor e Forma:SolidPeso molecular:465.98Glasmacinal
CAS:<p>Glasmacinal is a non-antibacterial macrolide compound with anti-inflammatory activities.</p>Fórmula:C37H62N2O10Cor e Forma:SolidPeso molecular:694.90Mt KARI-IN-1
<p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>Fórmula:C14H11N5O4S2Cor e Forma:SolidPeso molecular:377.4BDM91288
CAS:<p>BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].</p>Fórmula:C17H22ClN5Cor e Forma:SolidPeso molecular:331.84Gallinamide A
CAS:<p>Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.</p>Fórmula:C31H52N4O7Cor e Forma:SolidPeso molecular:592.77Ganaplacide hydrochloride
CAS:<p>Ganaplacide hydrochloride (KAF156 HCl) is an orally administered imidazopyrimidine antimalarial agent that inhibits Plasmodium PI4K activity.</p>Fórmula:C22H24ClF2N5OPureza:93.97%Cor e Forma:SoildPeso molecular:447.91GT-055
<p>GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.</p>Fórmula:C13H20F3N5O8SCor e Forma:SolidPeso molecular:463.39DENV-IN-6
CAS:<p>DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.</p>Fórmula:C23H26ClFN4OSCor e Forma:SolidPeso molecular:461MraY-IN-2
<p>MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.</p>Fórmula:C16H23N3O9Cor e Forma:SolidPeso molecular:401.37G092
<p>G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter protein. G092 has potential for antibacterial drug research.</p>Fórmula:C23H20Cl2N2O3Cor e Forma:SolidPeso molecular:443.32Cap-dependent endonuclease-IN-7
CAS:<p>Cap-dependent endonuclease-IN-7, a potent CEN inhibitor, blocks viral mRNA synthesis and virus spread, with research use for influenza A, B, C.</p>Fórmula:C36H28FN3O7SCor e Forma:SolidPeso molecular:665.69(4-Aminobenzoyl)-D-glutamic acid
CAS:<p>(4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth.</p>Fórmula:C12H14N2O5Cor e Forma:SolidPeso molecular:266.25LasR-IN-2
<p>LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.</p>Fórmula:C21H16ClN3O2Cor e Forma:SolidPeso molecular:377.82PfCLK3-IN-1
<p>PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.</p>Fórmula:C28H27ClN4O4Cor e Forma:SolidPeso molecular:518.99AN-12-H5
CAS:<p>AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.</p>Fórmula:C24H23N3O4S3Cor e Forma:SolidPeso molecular:513.65TAN-1057C
CAS:<p>TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).</p>Fórmula:C13H25N9O3Cor e Forma:SolidPeso molecular:355.4Pol I-IN-1
<p>Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition</p>Fórmula:C23H22N4O2Cor e Forma:SolidPeso molecular:386.45Chitin synthase inhibitor 9
<p>CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.</p>Fórmula:C24H25N3O6Cor e Forma:SolidPeso molecular:451.47DRF-8417
CAS:<p>DRF-8417 is an oxazolidinone antibiotic, active against both Gram-positive bacteria and fastidious Gram-negative bacteria. The MIC50 and MIC90 values of DRF-8417 for Gram-positive pathogens range between 0.06-1 mg/L.</p>Fórmula:C15H17N3O5SCor e Forma:SolidPeso molecular:351.38Ceftolozane TFA
CAS:<p>Ceftolozane TFA is a cephalosporin class antibiotic (antibiotic) designed to inhibit Gram-negative bacterial infections. Additionally, it can be utilized in the synthesis of novel antibiotics (antibiotic) that are more efficacious and safer.</p>Fórmula:C25H31F3N12O10S2Cor e Forma:SolidPeso molecular:780.71Antibacterial agent 75
<p>Antibacterial agent 75 re-sensitizes VRSA to vancomycin.</p>Fórmula:C22H28N6OCor e Forma:SolidPeso molecular:392.5DC-159a
CAS:<p>DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.</p>Fórmula:C21H23F2N3O40·5H2OCor e Forma:SolidPeso molecular:428.4295BMT-052
CAS:<p>BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).</p>Fórmula:C30H17D9F4N6O5Pureza:98%Cor e Forma:SolidPeso molecular:635.61Anticaries agent-1
CAS:<p>Anticaries agent-1 (Compound 21b) is utilized as an anticaries agent. It effectively inhibits biofilm formation with an IC50 of 77 μM and restricts the growth of S. mutans.</p>Fórmula:C15H12O4Cor e Forma:SolidPeso molecular:256.2538-Hydroxyerythromycin A
CAS:<p>8-Hydroxyerythromycin A is a semi-synthetic antibiotic with antibacterial activity.</p>Fórmula:C37H67NO14Cor e Forma:SolidPeso molecular:749.926TCMDC-136230
<p>TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.</p>Fórmula:C24H34N4O2SCor e Forma:SolidPeso molecular:442.62Chitinase-IN-4
<p>Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.</p>Fórmula:C21H24ClN7Cor e Forma:SolidPeso molecular:409.92
