HIV Protease
Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.
Foram encontrados 509 produtos para "HIV Protease".
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PF-3450074
CAS:PF-3450074 (PF-74) is a specific HIV-1 inhibitor, blocking viral replication and uncoating at submicromolar EC50=8-640 nM.Fórmula:C27H27N3O2Pureza:98.57%Cor e Forma:SolidPeso molecular:425.5222TERT-IN-1
CAS:TERT-IN-1 has anti-HIV activity and can be used to study HIV infection.Fórmula:C16H20ClN3SPureza:99.31%Cor e Forma:Yellow SolidPeso molecular:321.87Nevirapine
CAS:Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor.Fórmula:C15H14N4OPureza:99.58% - 99.59%Cor e Forma:SolidPeso molecular:266.2979Atazanavir
CAS:Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.Fórmula:C38H52N6O7Pureza:98% - 99.95%Cor e Forma:SolidPeso molecular:704.86GSK2838232
CAS:GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.Fórmula:C48H73ClN2O6Pureza:97.97%Cor e Forma:SolidPeso molecular:809.556(Rac)-Telinavir
CAS:N1 compound with anti-HIV activity; contains dimethyl, phenyl, quinoline groups.Fórmula:C33H44N6O5Pureza:98.12%Cor e Forma:SolidPeso molecular:604.7397(S)-(+)-N-3-Benzylnirvanol
CAS:(S)-(+)-N-3-Benzylnirvanol is a cytochrome P450 CYP2C19 inhibitor with a ki value of 82.5μM for CYP2C9 and 0.25μM for CYP2C19.Cost-effective and quality-assured.Fórmula:C18H18N2O2Pureza:98.90%Cor e Forma:White SolidPeso molecular:294.3477Pepstatin
CAS:Pepstatin (Pepsin Inhibitor S 735A) is a specific and orally aspartate protease inhibitor that also inhibits HIV protease activity. Cost effective and quality assured.Fórmula:C34H63N5O9Pureza:96.74% - 99.94%Cor e Forma:SolidPeso molecular:685.8921Ibalizumab
CAS:Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4Pureza:SDS-PAGE:96.4%;SEC-HPLC:97.7%Cor e Forma:Transparent LiquidPeso molecular:147.3 kDa (Predicted)Sodium copper chlorophyllin B
CAS:Sodium copper chlorophyllin B exerts antiviral activities against Influenza virus and HIV.Fórmula:C34H29CuN4Na3O7Pureza:≥98%Cor e Forma:SolidPeso molecular:738.13NBD-556
CAS:NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.Fórmula:C17H24ClN3O2Pureza:99.79%Cor e Forma:SolidPeso molecular:337.844Ritonavir
CAS:Ritonavir (ABT 538) inhibits HIV-1/2 proteases; serum proteins limit it but it enhances other HIV drugs by hindering P450 degradation.Fórmula:C37H48N6O5S2Pureza:99.38% - 99.96%Cor e Forma:White SolidPeso molecular:720.944Atazanavir sulfate
CAS:Atazanavir sulfate, an azapeptide HIV-protease inhibitor, treats HIV/AIDS alongside other anti-HIV drugs.Fórmula:C38H54N6O11SPureza:99.31% - 99.40%Cor e Forma:SolidPeso molecular:802.934Elsulfavirine
CAS:Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.Fórmula:C24H17BrCl2FN3O5SPureza:99.66%Cor e Forma:SolidPeso molecular:629.282Dolutegravir intermediate-1
CAS:Dolutegravir intermediate-1 is a synthetic precursor for HIV-1 treatment from patent WO 2016125192 A2.Fórmula:C13H17NO8Pureza:99.52%Cor e Forma:SolidPeso molecular:315.28Salicylanilide
CAS:Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.Fórmula:C13H11NO2Pureza:99.55% - 99.91%Cor e Forma:SolidPeso molecular:213.2319Clathrin-IN-1
CAS:Pitstop 2 inhibits clathrin-mediated endocytosis, targeting clathrin's terminal domain, with potential in cancer research.Fórmula:C20H13BrN2O3S2Pureza:99.53%Cor e Forma:SolidPeso molecular:473.363Fostemsavir Tris
CAS:Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment.Fórmula:C29H37N8O11PPureza:99.45%Cor e Forma:SolidPeso molecular:704.62Benfotiamine
CAS:Benfotiamine (S-Benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1), used as an antioxidant dietary supplement.Fórmula:C19H23N4O6PSPureza:99.2% - 99.91%Cor e Forma:White SolidPeso molecular:466.45GRL-07524
GRL-07524 (Compound 4e) is a potent HIV-1 protease inhibitor with a Ki of 0.22 nM. It contains an oxaspirocarbamate as the P2 ligand and demonstrates strong antiviral activity, with an EC50 of 210 nM. GRL-07524 can bind to the active site of HIV-1PR and crucial catalytic residues, interacting with one of four symmetric-independent molecules.Cor e Forma:Odour Solid
